hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_06678.1

Complex Portal: CPX-23398

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
ZNF524	Zinc finger protein 524	5	UniProt NCBI
TNFRSF13B	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD antigen CD267)	5	UniProt NCBI
LSM14B	Protein LSM14 homolog B (RNA-associated protein 55B) (hRAP55B)	5	UniProt NCBI
MAGED2	Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen)	5	UniProt NCBI
MBD6	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6)	4	UniProt NCBI
ZNF593	Zinc finger protein 593 (Zinc finger protein T86)	5	UniProt NCBI
RNF220	E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220)	5	UniProt NCBI
YY1AP1	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2)	5	UniProt NCBI
ZFP91	E3 ubiquitin-protein ligase ZFP91 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZFP91) (Zinc finger protein 757) (Zinc finger protein 91 homolog) (Zfp-91)	5	UniProt NCBI
SS18L2	SS18-like protein 2 (SYT homolog 2)	2	UniProt NCBI
RBM23	Probable RNA-binding protein 23 (CAPER beta) (CAPERbeta) (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2)	5	UniProt NCBI
BNC2	Zinc finger protein basonuclin-2	5	UniProt NCBI
RBM26	RNA-binding protein 26 (CTCL tumor antigen se70-2) (RNA-binding motif protein 26)	5	UniProt NCBI
FAF1	FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)	5	UniProt NCBI
BAG1	BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)	5	UniProt NCBI
NEUROG3	Neurogenin-3 (NGN-3) (Class A basic helix-loop-helix protein 7) (bHLHa7) (Protein atonal homolog 5)	5	UniProt NCBI
RBM27	RNA-binding protein 27 (RNA-binding motif protein 27)	4	UniProt NCBI
CLPX	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial	5	UniProt NCBI
ZNF579	Zinc finger protein 579	4	UniProt NCBI
CHCHD2	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (Aging-associated gene 10 protein) (HCV NS2 trans-regulated protein) (NS2TP)	5	UniProt NCBI
SCAF4	SR-related and CTD-associated factor 4 (CTD-binding SR-like protein RA4) (Splicing factor, arginine/serine-rich 15)	5	UniProt NCBI
POLDIP2	Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:3991	0.04984446262	0.0454545454545	CLPX	ClpX complex, hexameric
CORUM:6114	0.04984446262	0.0454545454545	BAG1	BAG1-HSC70 complex
CORUM:6115	0.04984446262	0.0454545454545	BAG1	BAG1-HSP70 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
SS18L2	YY1AP1	1.0	0.086	structurally_consistent (dimer)
POLDIP2	LSM14B	0.999	0.048
CHCHD2	RNF220	0.999	0.076
MAGED2	CHCHD2	0.999	0.076
CHCHD2	LSM14B	0.999	0.044
ZFP91	TNFRSF13B	0.998
CHCHD2	ZNF579	0.998	0.08	mutually_exclusive (Q14739)
TNFRSF13B	ZNF579	0.998
CHCHD2	POLDIP2	0.997	0.068	structurally_consistent (dimer)
TNFRSF13B	RBM26	0.997
CHCHD2	ZFP91	0.997	0.036
BAG1	CHCHD2	0.995	0.052
POLDIP2	CLPX	0.995	0.75
ZFP91	ZNF579	0.995	0.192
ZNF593	CHCHD2	0.994	0.1
RBM27	CHCHD2	0.993	0.044
CHCHD2	CLPX	0.993	0.038
CHCHD2	RBM23	0.992
CHCHD2	RBM26	0.992	0.042
RBM23	ZNF579	0.991
LSM14B	ZNF579	0.991	0.028
ZNF524	YY1AP1	0.99
MAGED2	ZFP91	0.99	0.03
NEUROG3	RBM27	0.99
NEUROG3	MAGED2	0.989
BAG1	ZNF579	0.989	0.084
YY1AP1	ZNF579	0.988	0.078
CHCHD2	SCAF4	0.988	0.022
NEUROG3	RBM26	0.988
CHCHD2	YY1AP1	0.987	0.092
ZFP91	RBM26	0.987	0.188
LSM14B	CLPX	0.985	0.048
BNC2	MBD6	0.985
NEUROG3	LSM14B	0.985
NEUROG3	CHCHD2	0.984
CHCHD2	FAF1	0.983	0.048
BNC2	POLDIP2	0.982
ZNF593	NEUROG3	0.981
CHCHD2	TNFRSF13B	0.98
ZFP91	POLDIP2	0.978	0.028
NEUROG3	BAG1	0.977
BNC2	LSM14B	0.976
BNC2	ZFP91	0.975
BNC2	ZNF579	0.974
SCAF4	RBM23	0.973
RBM27	ZFP91	0.972	0.132
ZNF524	ZNF579	0.971
RBM27	TNFRSF13B	0.971
ZFP91	RBM23	0.971
BAG1	CLPX	0.97	0.148
RNF220	LSM14B	0.967	0.06
ZFP91	RNF220	0.966	0.056
BAG1	YY1AP1	0.965	0.19
MBD6	CHCHD2	0.965
ZFP91	LSM14B	0.964	0.022
MBD6	ZNF579	0.963
CHCHD2	SS18L2	0.963	0.056
NEUROG3	ZFP91	0.962
BAG1	ZFP91	0.961	0.112
MBD6	LSM14B	0.961
BNC2	BAG1	0.959
BNC2	CHCHD2	0.957
BNC2	CLPX	0.957
BNC2	RNF220	0.954
ZFP91	SS18L2	0.951	0.11
POLDIP2	ZNF579	0.95	0.068
BAG1	LSM14B	0.947	0.133133333333
CLPX	ZNF579	0.944	0.05
ZNF524	SS18L2	0.944
MBD6	RNF220	0.943
RNF220	ZNF579	0.942	0.066
RNF220	POLDIP2	0.94	0.072
RNF220	CLPX	0.938	0.038
LSM14B	RBM23	0.934
RBM27	ZNF579	0.932	0.09
NEUROG3	YY1AP1	0.926
RBM27	BAG1	0.922	0.138
YY1AP1	RBM23	0.92
ZFP91	SCAF4	0.919	0.196
TNFRSF13B	RBM23	0.916
ZNF524	POLDIP2	0.904
MBD6	POLDIP2	0.899
RBM23	RBM26	0.898
RBM27	SCAF4	0.893	0.224
MAGED2	TNFRSF13B	0.887
POLDIP2	RBM23	0.884
MBD6	ZFP91	0.883
BAG1	MBD6	0.881
BAG1	POLDIP2	0.872	0.114
MBD6	CLPX	0.868
POLDIP2	TNFRSF13B	0.865
BAG1	RNF220	0.841	0.138
ZFP91	CLPX	0.84	0.024
RBM27	RBM23	0.84
SCAF4	RBM26	0.832	0.228
RNF220	FAF1	0.828	0.092
RBM27	YY1AP1	0.818	0.086
MAGED2	LSM14B	0.814	0.044
BAG1	FAF1	0.803	0.076
SCAF4	YY1AP1	0.803	0.076
RBM26	ZNF579	0.791	0.104
NEUROG3	POLDIP2	0.782
SS18L2	SCAF4	0.762	0.134
SS18L2	RBM26	0.747	0.1
ZNF593	LSM14B	0.746	0.036
RNF220	SS18L2	0.742	0.124
RNF220	RBM26	0.738	0.108
RBM27	RBM26	0.735	0.178
LSM14B	YY1AP1	0.728	0.09
SCAF4	ZNF579	0.711	0.142
RBM27	FAF1	0.707	0.112
MAGED2	SS18L2	0.701	0.054
RNF220	SCAF4	0.7	0.046
BAG1	RBM23	0.697
RBM27	SS18L2	0.697	0.132
MAGED2	FAF1	0.695	0.134
FAF1	RBM23	0.691
SS18L2	RBM23	0.689
ZFP91	FAF1	0.685	0.066
FAF1	LSM14B	0.675	0.068
RNF220	YY1AP1	0.662	0.134
NEUROG3	ZNF579	0.655
SS18L2	LSM14B	0.654	0.084
RNF220	RBM23	0.649
ZFP91	YY1AP1	0.646	0.078
FAF1	ZNF579	0.638	0.036
LSM14B	RBM26	0.624	0.058
ZNF593	FAF1	0.619	0.184
MAGED2	ZNF579	0.602	0.092
MAGED2	RBM23	0.594
SS18L2	FAF1	0.592	0.094
ZNF593	ZFP91	0.579	0.052
MAGED2	YY1AP1	0.577	0.09
BAG1	RBM26	0.574	0.126
ZNF593	BAG1	0.572	0.074
SCAF4	FAF1	0.57	0.062
MAGED2	BAG1	0.565	0.048
RBM27	RNF220	0.555	0.06
ZNF593	SCAF4	0.554	0.042
POLDIP2	FAF1	0.546	0.11
BAG1	SS18L2	0.532	0.096
FAF1	CLPX	0.529	0.07
RBM27	LSM14B	0.521	0.028
ZNF593	MAGED2	0.51	0.114
BAG1	SCAF4	0.503	0.12
ZNF593	RBM23	0.503
FAF1	RBM26	0.482	0.058
ZNF593	POLDIP2	0.464	0.106
SCAF4	LSM14B	0.463	0.052
ZNF593	RBM27	0.459	0.112
ZNF593	RBM26	0.459	0.062
ZNF593	YY1AP1	0.457	0.100023255814
YY1AP1	RBM26	0.423	0.138
FAF1	YY1AP1	0.345	0.084
POLDIP2	RBM26	0.342	0.064
SS18L2	ZNF579	0.324	0.124
RBM23	CLPX	0.319
ZNF593	RNF220	0.3	0.038023255814
BNC2	RBM23	0.283
RBM27	BNC2	0.283
MAGED2	BNC2	0.283
SS18L2	CLPX	0.274	0.05
MAGED2	RNF220	0.271	0.076
BNC2	SCAF4	0.262
RBM27	CLPX	0.239	0.052
ZNF593	BNC2	0.237
BNC2	RBM26	0.237
NEUROG3	CLPX	0.234
ZNF593	SS18L2	0.219	0.122
ZNF593	ZNF579	0.218	0.030023255814
YY1AP1	CLPX	0.17	0.134
BNC2	FAF1	0.156
ZNF593	CLPX	0.148	0.118615384615
MBD6	SS18L2	0.148
BNC2	SS18L2	0.148
POLDIP2	YY1AP1	0.146	0.094
MAGED2	RBM27	0.123	0.072
POLDIP2	SS18L2	0.113	0.09
MBD6	RBM23	0.11
POLDIP2	SCAF4	0.104	0.014
MBD6	SCAF4	0.102
MAGED2	RBM26	0.097	0.082
RBM27	POLDIP2	0.095	0.038
MBD6	FAF1	0.078
MBD6	YY1AP1	0.076
BNC2	YY1AP1	0.076
MBD6	RBM26	0.064
RBM27	MBD6	0.064
MAGED2	SCAF4	0.06	0.026
ZNF593	MBD6	0.055
RBM26	CLPX	0.048	0.13
MAGED2	MBD6	0.044
NEUROG3	FAF1	0.043
SCAF4	CLPX	0.041	0.036
MAGED2	CLPX	0.034	0.066
MAGED2	POLDIP2	0.028	0.042
MAGED2	ZNF524	0.016
TNFRSF13B	LSM14B	0.015

Related Complexes

Genename	Complexes
ZNF524	huMAP3_02476.1 huMAP3_04979.1 huMAP3_06678.1 huMAP3_10150.1
TNFRSF13B	huMAP3_05003.1 huMAP3_06678.1 huMAP3_09684.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14804.1
LSM14B	huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14804.1
MAGED2	huMAP3_00836.1 huMAP3_04536.1 huMAP3_04620.1 huMAP3_06678.1 huMAP3_06863.1 huMAP3_10150.1 huMAP3_13593.1
MBD6	huMAP3_02568.1 huMAP3_06678.1 huMAP3_07986.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1
ZNF593	huMAP3_00579.1 huMAP3_02568.1 huMAP3_05617.1 huMAP3_06431.1 huMAP3_06678.1 huMAP3_08339.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_14804.1
RNF220	huMAP3_02568.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1
YY1AP1	huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09682.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13012.1 huMAP3_13593.1
ZFP91	huMAP3_02568.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14804.1
SS18L2	huMAP3_02568.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09682.1 huMAP3_09852.1 huMAP3_10150.1
RBM23	huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14804.1
BNC2	huMAP3_02568.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14804.1
RBM26	huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09684.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_11453.1 huMAP3_13593.1 huMAP3_14804.1
FAF1	huMAP3_05181.1 huMAP3_05617.1 huMAP3_05715.1 huMAP3_06678.1 huMAP3_08557.1 huMAP3_10150.1 huMAP3_13357.1 huMAP3_13593.1
BAG1	huMAP3_02568.1 huMAP3_05064.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_09656.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14723.1
NEUROG3	huMAP3_00727.1 huMAP3_01455.1 huMAP3_06678.1 huMAP3_06851.1 huMAP3_07166.1 huMAP3_08339.1 huMAP3_08790.1 huMAP3_09915.1 huMAP3_13064.1
RBM27	huMAP3_02553.1 huMAP3_05165.1 huMAP3_06678.1 huMAP3_07273.1 huMAP3_07755.1 huMAP3_08111.1 huMAP3_08233.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09583.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_10299.1 huMAP3_13593.1 huMAP3_14804.1
CLPX	huMAP3_06678.1 huMAP3_08786.1 huMAP3_09668.1 huMAP3_09852.1 huMAP3_10525.1 huMAP3_13468.1 huMAP3_13593.1
ZNF579	huMAP3_06678.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_13593.1 huMAP3_14804.1
CHCHD2	huMAP3_02568.1 huMAP3_05617.1 huMAP3_06431.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_11301.1 huMAP3_13593.1 huMAP3_14804.1
SCAF4	huMAP3_04985.1 huMAP3_05617.1 huMAP3_06678.1 huMAP3_08893.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_11453.1 huMAP3_13593.1 huMAP3_14804.1
POLDIP2	huMAP3_02568.1 huMAP3_02624.1 huMAP3_06678.1 huMAP3_08786.1 huMAP3_08893.1 huMAP3_08944.1 huMAP3_09155.1 huMAP3_09852.1 huMAP3_10150.1 huMAP3_10485.1 huMAP3_11879.1 huMAP3_13593.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_06678.1

Complex Portal: CPX-23398