hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06679.1
Complex Portal: CPX-20721
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OSM | Oncostatin-M (OSM) | 5 | UniProt NCBI |
| IL6ST | Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) | 5 | UniProt NCBI |
| C5orf22 | UPF0489 protein C5orf22 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3229 | 0.0499419797295 | 0.5 | IL6ST | CDK9-IL6ST complex |
| CORUM:5579 | 0.0499419797295 | 0.5 | IL6ST | CNTF-CNTFR-gp130-LIFR complex |
| CORUM:5582 | 0.0499419797295 | 0.5 | IL6ST | LIFR-LIF-gp130 complex |
| HP:0025419 | 0.0499436884913 | 0.5 | IL6ST | Pulmonary pneumatocele |
| HP:0033332 | 0.0499436884913 | 0.5 | IL6ST | Elevated circulating amyloid A |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| C5orf22 | OSM | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| OSM | IL6ST | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| C5orf22 | IL6ST | 0.903 | 0.022 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes