hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06685.1
Complex Portal: CPX-25568
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | 5 | UniProt NCBI |
| GMPS | GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) | 5 | UniProt NCBI |
| BLVRB | Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3183 | 0.0249718442457 | 0.5 | PTPN11 | PDGFRA-SHP-2 complex, PDGF stimulated |
| WP:WP2253 | 0.0373151717536 | 0.5 | PTPN11 | Pilocytic astrocytoma |
| CORUM:3186 | 0.0499419797295 | 0.5 | PTPN11 | GRB2-SHP-2 complex, PDGF stimulated |
| CORUM:7441 | 0.0499419797295 | 0.5 | PTPN11 | HOOK1-SHP2 complex |
| HP:0005655 | 0.0499436884913 | 0.5 | PTPN11 | Multiple digital exostoses |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PTPN11 | BLVRB | 0.989 | 0.074 | bioplex_WMM bioplex3_WMM fraction | |
| PTPN11 | GMPS | 0.986 | 0.174 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| GMPS | BLVRB | 0.953 | 0.012 | bioplex_WMM bioplex3_WMM fraction |
Related Complexes