hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06695.1
Complex Portal: CPX-16368
Confidence: Very High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SGO1 | Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1) | 5 | UniProt   NCBI |
| FOXC2 | Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14) | 5 | UniProt   NCBI |
| PPP4C | Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X) | 5 | UniProt   NCBI |
| PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) | 5 | UniProt   NCBI |
| IER5 | Immediate early response gene 5 protein | 5 | UniProt   NCBI |
| PRR14 | Proline-rich protein 14 | 5 | UniProt   NCBI |
| IGBP1 | Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16) | 5 | UniProt   NCBI |
| PPP4R1 | Serine/threonine-protein phosphatase 4 regulatory subunit 1 | 4 | UniProt   NCBI |
| FECH | Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase) | 5 | UniProt   NCBI |
| CCDC6 | Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4) | 5 | UniProt   NCBI |
| PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16) | 5 | UniProt   NCBI |
| PABIR1 | PPP2R1A-PPP2R2A-interacting phosphatase regulator 1 (PABIR family member 1) | 5 | UniProt   NCBI |
| FOXC1 | Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3) | 5 | UniProt   NCBI |
| PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform (IMYPNO1) (PP2A subunit B isoform B55-gamma) (PP2A subunit B isoform PR55-gamma) (PP2A subunit B isoform R2-gamma) (PP2A subunit B isoform gamma) | 4 | UniProt   NCBI |
| ANKLE2 | Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) | 5 | UniProt   NCBI |
| SERTAD2 | SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2) | 5 | UniProt   NCBI |
| PPFIA3 | Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3) | 5 | UniProt   NCBI |
| SERTAD4 | SERTA domain-containing protein 4 | 2 | UniProt   NCBI |
| PPME1 | Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) | 5 | UniProt   NCBI |
| PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha) | 5 | UniProt   NCBI |
| SGO2 | Shugoshin 2 (Shugoshin-2) (Shugoshin-like 2) (Tripin) | 5 | UniProt   NCBI |
| PPFIA1 | Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) | 5 | UniProt   NCBI |
| IER2 | Immediate early response gene 2 protein (Protein ETR101) | 5 | UniProt   NCBI |
| PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C) | 5 | UniProt   NCBI |
| TBCCD1 | TBCC domain-containing protein 1 | 4 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   WP:WP4949 | 1.36154247425e-09 | 0.304347826087 | PPP4R1 IGBP1 CCDC6 PPP2R5D PPP4C PPP2CB PPP2CA | 16p11 2 proximal deletion syndrome |
|   GO:0008287 | 4.16343453606e-08 | 0.304347826087 | PPP4R1 PPP2CA IER5 PPP2R5D PPP2CB PPP4C PPP2R2C | protein serine/threonine phosphatase complex |
|   GO:1903293 | 4.16343453606e-08 | 0.304347826087 | PPP4R1 PPP2CA IER5 PPP2R5D PPP2CB PPP4C PPP2R2C | phosphatase complex |
|   WP:WP5117 | 1.25623771938e-07 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Cohesin complex Cornelia de Lange syndrome |
|   GO:0019888 | 2.02642773749e-07 | 0.304347826087 | PPP4R1 IGBP1 PPP2R5D PPME1 PPP2R2C PABIR1 ANKLE2 | protein phosphatase regulator activity |
|   GO:0019208 | 6.011814823e-07 | 0.304347826087 | PPP4R1 IGBP1 PPP2R5D PPME1 PPP2R2C PABIR1 ANKLE2 | phosphatase regulator activity |
|   GO:0000159 | 2.56156525716e-06 | 0.217391304348 | PPP2R2C IER5 PPP2CA PPP2R5D PPP2CB | protein phosphatase type 2A complex |
|   WP:WP500 | 3.72648565168e-05 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | Glycogen synthesis and degradation |
|   REAC:R-HSA-163767 | 3.82811230328e-05 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | PP2A-mediated dephosphorylation of key metabolic factors |
|   REAC:R-HSA-141424 | 8.79017030163e-05 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Amplification of signal from the kinetochores |
|   REAC:R-HSA-141444 | 8.79017030163e-05 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
|   REAC:R-HSA-69618 | 0.000195988930025 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Mitotic Spindle Checkpoint |
|   CORUM:7251 | 0.00022469866415 | 0.0869565217391 | IGBP1 PPP2CA | IGBP1-MID1-PPP2CA complex |
|   CORUM:5876 | 0.00022469866415 | 0.0869565217391 | PPME1 PPP2CA | PPP2R1A-PPP2R1B-PPP2CA-PPME1-EIF4A1 complex |
|   REAC:R-HSA-9634600 | 0.000239391769139 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Regulation of glycolysis by fructose 2,6-bisphosphate metabolism |
|   REAC:R-HSA-9648025 | 0.000245525602739 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | EML4 and NUDC in mitotic spindle formation |
|   REAC:R-HSA-68882 | 0.000309255063402 | 0.260869565217 | PPP2CA SGO2 PPP2CB PPP2R5D SGO1 ANKLE2 | Mitotic Anaphase |
|   REAC:R-HSA-202670 | 0.000310889866803 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | ERKs are inactivated |
|   REAC:R-HSA-2555396 | 0.000317447058649 | 0.260869565217 | PPP2CA SGO2 PPP2CB PPP2R5D SGO1 ANKLE2 | Mitotic Metaphase and Anaphase |
|   REAC:R-HSA-2500257 | 0.000344872996068 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Resolution of Sister Chromatid Cohesion |
|   REAC:R-HSA-5467340 | 0.000395271884097 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | AXIN missense mutants destabilize the destruction complex |
|   REAC:R-HSA-4839748 | 0.000395271884097 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Signaling by AMER1 mutants |
|   REAC:R-HSA-4839744 | 0.000395271884097 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Signaling by APC mutants |
|   REAC:R-HSA-4839735 | 0.000395271884097 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Signaling by AXIN mutants |
|   REAC:R-HSA-5467348 | 0.000395271884097 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Truncations of AMER1 destabilize the destruction complex |
|   REAC:R-HSA-5467337 | 0.000395271884097 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | APC truncation mutants have impaired AXIN binding |
|   REAC:R-HSA-5339716 | 0.000493582723072 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Signaling by GSK3beta mutants |
|   REAC:R-HSA-4839743 | 0.000493582723072 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Signaling by CTNNB1 phospho-site mutants |
|   REAC:R-HSA-5358751 | 0.000493582723072 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | CTNNB1 S45 mutants aren't phosphorylated |
|   REAC:R-HSA-5358752 | 0.000493582723072 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | CTNNB1 T41 mutants aren't phosphorylated |
|   REAC:R-HSA-5358747 | 0.000493582723072 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | CTNNB1 S33 mutants aren't phosphorylated |
|   REAC:R-HSA-5358749 | 0.000493582723072 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | CTNNB1 S37 mutants aren't phosphorylated |
|   REAC:R-HSA-5663220 | 0.000530568681891 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | RHO GTPases Activate Formins |
|   REAC:R-HSA-432142 | 0.000606862915293 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Platelet sensitization by LDL |
|   KEGG:03015 | 0.000700474986871 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | mRNA surveillance pathway |
|   REAC:R-HSA-196299 | 0.00073614863329 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Beta-catenin phosphorylation cascade |
|   KEGG:04136 | 0.000827868214757 | 0.130434782609 | PPP2CA IGBP1 PPP2CB | Autophagy - other |
|   REAC:R-HSA-389513 | 0.000882471701966 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | CTLA4 inhibitory signaling |
|   KEGG:04071 | 0.00114436324865 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | Sphingolipid signaling pathway |
|   KEGG:04660 | 0.00114436324865 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | T cell receptor signaling pathway |
|   KEGG:04114 | 0.00118889808909 | 0.173913043478 | PPP2CA PPP2CB SGO1 PPP2R5D | Oocyte meiosis |
|   REAC:R-HSA-180024 | 0.00123033552123 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | DARPP-32 events |
|   KEGG:04728 | 0.00143096586249 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | Dopaminergic synapse |
|   REAC:R-HSA-198753 | 0.00143391828595 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | ERK/MAPK targets |
|   KEGG:04152 | 0.00164926671987 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | AMPK signaling pathway |
|   KEGG:04261 | 0.00202132201891 | 0.173913043478 | PPP2R2C PPP2CA PPP2R5D PPP2CB | Adrenergic signaling in cardiomyocytes |
|   REAC:R-HSA-69273 | 0.0024695445471 | 0.130434782609 | PPP2CA PPP2CB PPME1 | Cyclin A/B1/B2 associated events during G2/M transition |
|   REAC:R-HSA-2467813 | 0.00270486279081 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Separation of Sister Chromatids |
|   REAC:R-HSA-68877 | 0.0035863201202 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Mitotic Prometaphase |
|   REAC:R-HSA-69278 | 0.00359692845069 | 0.304347826087 | PPP2CA SGO2 PPME1 PPP2CB PPP2R5D SGO1 ANKLE2 | Cell Cycle, Mitotic |
|   REAC:R-HSA-5673000 | 0.00433696122827 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | RAF activation |
|   REAC:R-HSA-450282 | 0.00433696122827 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | MAPK targets/ Nuclear events mediated by MAP kinases |
|   REAC:R-HSA-4641262 | 0.00479670839147 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Disassembly of the destruction complex and recruitment of AXIN to the membrane |
|   KEGG:04110 | 0.0051237735471 | 0.173913043478 | PPP2CA PPP2CB SGO1 PPP2R5D | Cell cycle |
|   WP:WP2857 | 0.00530921178014 | 0.173913043478 | FOXC1 FOXC2 PPP2CA CCDC6 | Mesodermal commitment pathway |
|   REAC:R-HSA-4791275 | 0.00581026889635 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Signaling by WNT in cancer |
|   REAC:R-HSA-68886 | 0.00736887440163 | 0.260869565217 | PPP2CA SGO2 PPP2CB PPP2R5D SGO1 ANKLE2 | M Phase |
|   REAC:R-HSA-5675221 | 0.0089377700796 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Negative regulation of MAPK pathway |
|   REAC:R-HSA-1640170 | 0.0137061207617 | 0.304347826087 | PPP2CA SGO2 PPME1 PPP2CB PPP2R5D SGO1 ANKLE2 | Cell Cycle |
|   WP:WP2436 | 0.0194071681392 | 0.0869565217391 | PPP2CB PPP2CA | Dopamine metabolism |
|   REAC:R-HSA-69620 | 0.0200249713124 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | Cell Cycle Checkpoints |
|   KEGG:05142 | 0.0210830811815 | 0.130434782609 | PPP2CA PPP2CB PPP2R2C | Chagas disease |
|   REAC:R-HSA-198725 | 0.0258512651339 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Nuclear Events (kinase and transcription factor activation) |
|   REAC:R-HSA-195258 | 0.0265013996547 | 0.217391304348 | SGO2 PPP2CA PPP2CB SGO1 PPP2R5D | RHO GTPase Effectors |
|   REAC:R-HSA-450294 | 0.028831142995 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | MAP kinase activation |
|   REAC:R-HSA-388841 | 0.0304016562135 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Costimulation by the CD28 family |
|   REAC:R-HSA-2465910 | 0.0341274633537 | 0.0869565217391 | PPP2CB PPP2CA | MASTL Facilitates Mitotic Progression |
|   REAC:R-HSA-448424 | 0.0390945291887 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Interleukin-17 signaling |
|   WP:WP3927 | 0.0397994877749 | 0.0869565217391 | FOXC2 FOXC1 | BMP signaling in eyelid development |
|   WP:WP4830 | 0.044731571894 | 0.0869565217391 | FOXC2 FOXC1 | GDNF RET signaling axis |
|   REAC:R-HSA-70171 | 0.0450132219183 | 0.130434782609 | PPP2CA PPP2R5D PPP2CB | Glycolysis |
|   CORUM:1543 | 0.0498014438088 | 0.0434782608696 | PPP2CA | PPP2CA-PPP2R1A complex |
|   REAC:R-HSA-264642 | 0.0499578070164 | 0.0869565217391 | PPFIA1 PPFIA3 | Acetylcholine Neurotransmitter Release Cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
|  PPP2R1A |  PPP2CA | 1.0 | 0.99           |
structurally_consistent (Q16537)        
structurally_consistent (dimer)         |
|  PPP4R1 |  CCDC6 | 1.0 | 0.072           |          |
|  PPP2R5D |  PPP2CB | 1.0 | 0.204           |
structurally_consistent (dimer)        
|
|  PPP4C |  CCDC6 | 1.0 | 0.142           |
structurally_consistent (dimer)        
|
|  PPP4R1 |  PPP4C | 1.0 | 0.18           |
structurally_consistent (dimer)        
|
|  PPP2R2C |  PPP2CB | 1.0 | 0.172           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  PPP2CB | 1.0 | 0.602           |
structurally_consistent (Q16537)        
structurally_consistent (dimer)         |
|  PPP2R1A |  PPFIA1 | 1.0 | 0.212           |          |
|  PPP2CB |  PPP2CA | 1.0 | 0.412           |
structurally_consistent (dimer)        
|
|  SERTAD4 |  PPP2CB | 0.999 |            |
structurally_consistent (P63151)        
|
|  PPME1 |  PPP2CB | 0.999 |            |
structurally_consistent (dimer)        
|
|  PPP2R2C |  PPP2CA | 0.999 | 0.254           |
structurally_consistent (dimer)        
|
|  PABIR1 |  PPP2CB | 0.999 | 0.164           |
mixed_interface        
|
|  SERTAD4 |  PPP2CA | 0.999 |            |
mutually_exclusive (Q66LE6)        
|
|  SERTAD4 |  PPP2R1A | 0.999 |            |          |
|  SERTAD4 |  PPP2R2C | 0.999 |            |
mutually_exclusive (Q66LE6)        
structurally_consistent (dimer)         |
|  PPP4C |  PPP2CB | 0.999 | 0.354           |
structurally_consistent (dimer)        
|
|  IGBP1 |  PPP4C | 0.999 | 0.282           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  PPP4C | 0.999 | 0.286133333333           |          |
|  PABIR1 |  PPP2R1A | 0.999 | 0.174           |          |
|  PPP2R1A |  IER2 | 0.998 |            |          |
|  PPP2R1A |  PPP2R5D | 0.998 | 0.456           |
structurally_consistent (dimer)        
|
|  SGO1 |  PPP2R5D | 0.998 | 0.07           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  PPP2R2C | 0.998 | 0.458           |
structurally_consistent (dimer)        
|
|  PRR14 |  PPP2R5D | 0.998 | 0.084           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  PRR14 | 0.998 | 0.124           |          |
|  IER2 |  PPP2CB | 0.998 |            |
structurally_consistent (dimer)        
|
|  PPFIA1 |  PPP2CB | 0.997 | 0.136           |
structurally_consistent (dimer)        
|
|  SERTAD2 |  PPP2CB | 0.997 |            |
structurally_consistent (P63151)        
|
|  TBCCD1 |  PPP2R1A | 0.997 |            |
structurally_consistent (Q9Y5P8)        
structurally_consistent (dimer)         |
|  SERTAD2 |  PPP2CA | 0.996 |            |
structurally_consistent (dimer)        
|
|  PPP4C |  PPP2CA | 0.996 | 0.448           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  SGO1 | 0.996 | 0.194533333333           |
structurally_consistent (Q14738)        
|
|  TBCCD1 |  PPP2CB | 0.996 |            |
mutually_exclusive (P67775)        
structurally_consistent (dimer)         |
|  PPFIA1 |  PPFIA3 | 0.995 | 0.086           |          |
|  PABIR1 |  FOXC2 | 0.995 | 0.082           |          |
|  PPP2R1A |  SERTAD2 | 0.995 |            |          |
|  SGO1 |  PPP2CB | 0.995 | 0.184           |
structurally_consistent (Q14738)        
|
|  PRR14 |  PPP2CB | 0.995 | 0.199142857143           |          |
|  PABIR1 |  PPP2R2C | 0.995 | 0.098           |
mutually_exclusive (P67775)        
|
|  PPP2R1A |  FECH | 0.994 | 0.076           |          |
|  PPME1 |  PPP2CA | 0.994 |            |
structurally_consistent (dimer)        
|
|  ANKLE2 |  PPP2CB | 0.994 | 0.084           |
structurally_consistent (dimer)        
|
|  SGO1 |  PPP2CA | 0.994 | 0.182           |          |
|  IGBP1 |  PPP2CB | 0.993 | 0.27           |
mutually_exclusive (P60510)        
structurally_consistent (dimer)         |
|  PPP2R1A |  SGO2 | 0.993 | 0.4           |          |
|  PPP4R1 |  PPP2CB | 0.993 | 0.234           |
structurally_consistent (dimer)        
|
|  CCDC6 |  PPP2CB | 0.992 | 0.122           |
mutually_exclusive (P60510)        
structurally_consistent (dimer)         |
|  IER5 |  PPP2R2C | 0.992 |            |          |
|  IGBP1 |  PPP2CA | 0.992 | 0.29           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  FOXC1 | 0.992 | 0.42           |          |
|  PPFIA3 |  PPP2CB | 0.992 | 0.098           |          |
|  PPP2R1A |  PPP4R1 | 0.992 | 0.284           |          |
|  PABIR1 |  PPP2CA | 0.991 | 0.158           |
structurally_consistent (dimer)        
|
|  PPME1 |  FOXC2 | 0.991 |            |          |
|  PPP2R5D |  PPP2CA | 0.99 | 0.306           |
structurally_consistent (dimer)        
|
|  PPP2R1A |  FOXC2 | 0.99 | 0.31           |          |
|  ANKLE2 |  PPP4R1 | 0.989 | 0.04           |
mutually_exclusive (P62714)        
|
|  PPP2R1A |  CCDC6 | 0.989 | 0.224           |          |
|  PPP2R1A |  IER5 | 0.989 |            |          |
|  FOXC1 |  FOXC2 | 0.988 | 0.154           |          |
|  FOXC2 |  PPP2CA | 0.988 | 0.138           |          |
|  PPME1 |  PPP4C | 0.987 |            |
structurally_consistent (dimer)        
|
|  PPFIA1 |  CCDC6 | 0.986 | 0.036           |
mutually_exclusive (P62714)        
|
|  PPP4C |  PPP2R5D | 0.986 | 0.172           |          |
|  PPFIA1 |  PPP2R5D | 0.986 | 0.092           |          |
|  FECH |  PPP2CB | 0.985 | 0.108           |          |
|  IGBP1 |  CCDC6 | 0.985 | 0.102           |          |
|  PPP2R2C |  SERTAD2 | 0.985 |            |          |
|  PPME1 |  SGO2 | 0.985 |            |          |
|  IGBP1 |  PPP4R1 | 0.983 | 0.154           |          |
|  FECH |  PPP4R1 | 0.983 | 0.018           |          |
|  PRR14 |  CCDC6 | 0.981 | 0.062           |          |
|  PPFIA3 |  PPP2R5D | 0.981 | 0.094           |          |
|  PPME1 |  PPP2R5D | 0.98 |            |          |
|  PPME1 |  PRR14 | 0.98 |            |          |
|  PPFIA1 |  PPP4R1 | 0.979 | 0.054           |          |
|  PPP2R2C |  IER2 | 0.978 |            |          |
|  PPP4R1 |  PPP2R5D | 0.976 | 0.106           |          |
|  PPME1 |  PPP2R1A | 0.974 |            |
structurally_consistent (dimer)        
|
|  SGO2 |  FOXC2 | 0.974 | 0.118           |          |
|  FOXC1 |  PRR14 | 0.973 | 0.078           |          |
|  ANKLE2 |  FECH | 0.971 | 0.026           |          |
|  PPFIA1 |  FECH | 0.971 | 0.018           |          |
|  FOXC2 |  PPP2CB | 0.97 | 0.208           |          |
|  PPFIA3 |  CCDC6 | 0.969 | 0.09           |          |
|  PABIR1 |  SGO2 | 0.969 | 0.132           |          |
|  TBCCD1 |  PPP4R1 | 0.969 |            |          |
|  PABIR1 |  FOXC1 | 0.967 | 0.11           |          |
|  ANKLE2 |  PPP2R1A | 0.967 | 0.16           |
mutually_exclusive (P62714)        
structurally_consistent (dimer)         |
|  FOXC1 |  PPP2CA | 0.966 | 0.152           |          |
|  PPP4R1 |  PPP2CA | 0.964 | 0.204           |          |
|  TBCCD1 |  PPME1 | 0.963 |            |
mutually_exclusive (P30153)        
|
|  ANKLE2 |  PPME1 | 0.962 |            |
mutually_exclusive (P62714)        
|
|  PPFIA1 |  PPP2CA | 0.962 | 0.138           |
mutually_exclusive (P62714)        
|
|  PPP4R1 |  PRR14 | 0.961 | 0.056           |          |
|  FECH |  PPFIA3 | 0.961 | 0.062           |          |
|  PPFIA3 |  PRR14 | 0.961 | 0.054           |          |
|  PPP2R5D |  CCDC6 | 0.96 | 0.072           |          |
|  TBCCD1 |  PABIR1 | 0.96 |            |          |
|  PPME1 |  PPFIA1 | 0.96 |            |
mutually_exclusive (P62714)        
|
|  FECH |  CCDC6 | 0.959 | 0.012           |          |
|  TBCCD1 |  PPP2CA | 0.959 |            |
structurally_consistent (dimer)        
|
|  ANKLE2 |  PPFIA3 | 0.959 | 0.156           |          |
|  FOXC1 |  PPP4R1 | 0.958 | 0.042           |          |
|  PPME1 |  PPP4R1 | 0.957 |            |
structurally_consistent (P60510)        
|
|  TBCCD1 |  FECH | 0.955 |            |          |
|  FOXC1 |  PPP2CB | 0.952 | 0.178           |          |
|  PABIR1 |  IER5 | 0.951 |            |          |
|  FECH |  PPP2R5D | 0.95 | 0.054           |          |
|  FECH |  PPP4C | 0.948 | 0.046           |          |
|  PPFIA3 |  PPP4C | 0.946 | 0.094           |          |
|  ANKLE2 |  PABIR1 | 0.945 | 0.084           |          |
|  IER2 |  PPP2CA | 0.944 |            |
structurally_consistent (dimer)        
|
|  PPP2R2C |  PPP4C | 0.941 | 0.2           |          |
|  ANKLE2 |  PPP2R5D | 0.941 | 0.074           |          |
|  ANKLE2 |  CCDC6 | 0.94 | 0.046           |          |
|  PPP2R1A |  PPFIA3 | 0.939 | 0.218           |          |
|  ANKLE2 |  PRR14 | 0.939 | 0.064           |          |
|  TBCCD1 |  PRR14 | 0.937 |            |          |
|  PPME1 |  FECH | 0.937 |            |          |
|  TBCCD1 |  CCDC6 | 0.936 |            |          |
|  TBCCD1 |  PPFIA3 | 0.936 |            |          |
|  SGO2 |  PPP2CA | 0.933 | 0.352           |          |
|  PPFIA3 |  PPP4R1 | 0.929 | 0.064           |          |
|  IER5 |  PPP2CB | 0.927 |            |
structurally_consistent (P63151)        
|
|  FECH |  IGBP1 | 0.927 | 0.026           |          |
|  FOXC1 |  PPFIA3 | 0.924 | 0.074           |          |
|  TBCCD1 |  FOXC1 | 0.921 |            |          |
|  CCDC6 |  PPP2CA | 0.919 | 0.126           |
mutually_exclusive (P60510)        
structurally_consistent (dimer)         |
|  PPME1 |  PABIR1 | 0.917 |            |          |
|  PRR14 |  PPP2CA | 0.917 | 0.108           |          |
|  ANKLE2 |  TBCCD1 | 0.916 |            |
mutually_exclusive (P62714)        
|
|  FOXC1 |  PPP2R5D | 0.914 | 0.102           |          |
|  PABIR1 |  PRR14 | 0.913 | 0.096           |          |
|  TBCCD1 |  PPP2R5D | 0.913 |            |          |
|  SERTAD2 |  PPP4C | 0.913 |            |          |
|  IER5 |  PPP2CA | 0.911 |            |          |
|  SGO2 |  FOXC1 | 0.911 | 0.086           |          |
|  ANKLE2 |  PPFIA1 | 0.902 | 0.046           |
mutually_exclusive (P62714)        
|
|  SGO2 |  PRR14 | 0.895 | 0.12           |          |
|  TBCCD1 |  PPFIA1 | 0.894 |            |          |
|  PABIR1 |  FECH | 0.892 | 0.06           |          |
|  PPME1 |  PPFIA3 | 0.89 |            |          |
|  PABIR1 |  PPFIA3 | 0.888 | 0.078           |          |
|  IER5 |  IER2 | 0.884 |            |          |
|  FECH |  PRR14 | 0.861 | 0.034           |          |
|  PPFIA1 |  PPP4C | 0.861 | 0.032           |
mutually_exclusive (P62714)        
|
|  FOXC1 |  FECH | 0.857 | 0.036           |          |
|  PPFIA1 |  IGBP1 | 0.856 | 0.056           |          |
|  FOXC1 |  PPFIA1 | 0.854 | 0.084           |          |
|  PPP2R1A |  IGBP1 | 0.853 | 0.204           |          |
|  PPME1 |  IER5 | 0.829 |            |          |
|  FECH |  PPP2CA | 0.819 | 0.126           |          |
|  PPFIA1 |  PRR14 | 0.818 | 0.038           |          |
|  PPME1 |  FOXC1 | 0.815 |            |          |
|  PPME1 |  IER2 | 0.807 |            |          |
|  PRR14 |  PPP4C | 0.806 | 0.058           |          |
|  PPME1 |  SERTAD2 | 0.784 |            |          |
|  IER5 |  PPP4C | 0.783 |            |
mutually_exclusive (Q66LE6)        
|
|  FOXC1 |  CCDC6 | 0.782 | 0.106           |          |
|  IGBP1 |  PPP2R5D | 0.771 | 0.112           |          |
|  IER2 |  PPP4C | 0.743 |            |          |
|  IER5 |  SERTAD2 | 0.737 |            |          |
|  PABIR1 |  PPP2R5D | 0.73 | 0.106           |
mutually_exclusive (P67775)        
|
|  PPME1 |  CCDC6 | 0.713 |            |          |
|  PABIR1 |  PPFIA1 | 0.713 | 0.122           |
mutually_exclusive (P62714)        
|
|  PABIR1 |  IER2 | 0.699 |            |          |
|  IER5 |  FOXC1 | 0.675 |            |          |
|  FOXC1 |  IER2 | 0.645 |            |          |
|  IER2 |  SERTAD2 | 0.626 |            |          |
|  SERTAD4 |  IER5 | 0.573 |            |          |
|  PABIR1 |  CCDC6 | 0.573 | 0.062           |          |
|  IER5 |  FOXC2 | 0.572 |            |          |
|  FOXC1 |  PPP4C | 0.553 | 0.068           |          |
|  SGO2 |  IER2 | 0.543 |            |          |
|  ANKLE2 |  IGBP1 | 0.533 | 0.054           |          |
|  IER2 |  FOXC2 | 0.53 |            |          |
|  ANKLE2 |  FOXC1 | 0.527 | 0.092           |          |
|  SERTAD4 |  FOXC2 | 0.502 |            |          |
|  FOXC1 |  SERTAD2 | 0.481 |            |          |
|  FOXC1 |  PPP2R2C | 0.48 | 0.062           |          |
|  SERTAD4 |  PABIR1 | 0.474 |            |          |
|  PABIR1 |  SERTAD2 | 0.471 |            |          |
|  TBCCD1 |  PPP4C | 0.453 |            |
mutually_exclusive (P62714)        
|
|  PABIR1 |  PPP4C | 0.436 | 0.148           |          |
|  SGO1 |  PRR14 | 0.423 | 0.092           |
mutually_exclusive (Q14738)        
|
|  TBCCD1 |  SGO2 | 0.423 |            |          |
|  SGO1 |  CCDC6 | 0.416 | 0.08           |          |
|  TBCCD1 |  IER5 | 0.41 |            |          |
|  IER5 |  PPP2R5D | 0.401 |            |          |
|  PPME1 |  SGO1 | 0.396 |            |          |
|  TBCCD1 |  SERTAD2 | 0.388 |            |          |
|  SGO2 |  PPP2CB | 0.385 | 0.398857142857           |          |
|  PPP2R2C |  PRR14 | 0.383 | 0.036           |          |
|  SERTAD2 |  PPP2R5D | 0.378 |            |
mutually_exclusive (P67775)        
|
|  IER5 |  PPFIA3 | 0.378 |            |          |
|  SERTAD4 |  PPP4C | 0.373 |            |
mutually_exclusive (Q66LE6)        
|
|  FOXC1 |  SGO1 | 0.369 | 0.114           |          |
|  TBCCD1 |  PPP2R2C | 0.356 |            |          |
|  TBCCD1 |  IER2 | 0.356 |            |
mutually_exclusive (P67775)        
|
|  IER2 |  PRR14 | 0.356 |            |          |
|  SERTAD2 |  PRR14 | 0.356 |            |          |
|  TBCCD1 |  SGO1 | 0.353 |            |          |
|  IER5 |  PRR14 | 0.343 |            |          |
|  IER5 |  PPFIA1 | 0.334 |            |          |
|  SERTAD4 |  IER2 | 0.334 |            |          |
|  SERTAD4 |  PPME1 | 0.332 |            |          |
|  SGO2 |  PPP4C | 0.33 | 0.218           |          |
|  IGBP1 |  PRR14 | 0.298 | 0.04           |          |
|  PPFIA1 |  SGO1 | 0.283 | 0.088           |          |
|  ANKLE2 |  PPP4C | 0.277 | 0.144           |          |
|  SGO1 |  PPP4R1 | 0.273 | 0.048           |          |
|  PPME1 |  PPP2R2C | 0.259 |            |          |
|  SERTAD2 |  PPFIA3 | 0.255 |            |          |
|  FOXC2 |  PRR14 | 0.248 | 0.098           |          |
|  FOXC2 |  PPFIA3 | 0.248 | 0.1           |          |
|  TBCCD1 |  FOXC2 | 0.248 |            |          |
|  FOXC2 |  PPP2R5D | 0.232 | 0.122           |          |
|  FOXC2 |  PPP4R1 | 0.232 | 0.112           |          |
|  FOXC2 |  CCDC6 | 0.232 | 0.156           |          |
|  SGO2 |  FECH | 0.232 | 0.074           |          |
|  IER2 |  PPFIA3 | 0.22 |            |          |
|  IER2 |  PPP2R5D | 0.22 |            |
mutually_exclusive (P67775)        
|
|  IER2 |  PPFIA1 | 0.22 |            |          |
|  SERTAD2 |  PPFIA1 | 0.22 |            |          |
|  SERTAD2 |  FOXC2 | 0.214 |            |          |
|  SGO1 |  FECH | 0.208 | 0.136           |          |
|  FECH |  FOXC2 | 0.192 | 0.042           |          |
|  SGO2 |  PPFIA3 | 0.192 | 0.088           |          |
|  IER5 |  CCDC6 | 0.188 |            |          |
|  PPP2R2C |  PPFIA3 | 0.188 | 0.03           |          |
|  SERTAD2 |  CCDC6 | 0.188 |            |
mutually_exclusive (P67775)        
|
|  PPFIA3 |  IGBP1 | 0.179 | 0.06           |          |
|  PPFIA3 |  PPP2CA | 0.174 | 0.124           |          |
|  PPME1 |  IGBP1 | 0.171 |            |          |
|  SERTAD4 |  SGO2 | 0.164 |            |          |
|  SGO2 |  IER5 | 0.164 |            |          |
|  SERTAD4 |  SERTAD2 | 0.162 |            |          |
|  ANKLE2 |  SGO1 | 0.156 | 0.05           |          |
|  SGO2 |  IGBP1 | 0.154 | 0.124           |          |
|  IER2 |  CCDC6 | 0.15 |            |          |
|  SERTAD4 |  FOXC1 | 0.145 |            |          |
|  FOXC2 |  PPP4C | 0.143 | 0.1           |          |
|  PPP2R2C |  PPFIA1 | 0.133 | 0.082           |          |
|  ANKLE2 |  IER5 | 0.133 |            |          |
|  SERTAD2 |  FECH | 0.12 |            |          |
|  IER5 |  FECH | 0.12 |            |          |
|  IER2 |  FECH | 0.11 |            |          |
|  SGO1 |  IGBP1 | 0.107 | 0.118           |          |
|  SGO1 |  PPFIA3 | 0.106 | 0.108           |          |
|  PPP2R2C |  SGO1 | 0.106 | 0.13           |          |
|  SERTAD4 |  PPP2R5D | 0.102 |            |          |
|  ANKLE2 |  SERTAD2 | 0.099 |            |          |
|  PPP2R2C |  PPP2R5D | 0.097 | 0.042           |          |
|  SGO2 |  SGO1 | 0.093 | 0.222           |          |
|  SERTAD4 |  PPFIA1 | 0.087 |            |          |
|  SERTAD4 |  PRR14 | 0.087 |            |          |
|  SGO2 |  CCDC6 | 0.082 | 0.128           |          |
|  PPP2R2C |  FECH | 0.079 | 0.02           |          |
|  PPP2R2C |  IGBP1 | 0.077 | 0.054           |          |
|  PABIR1 |  SGO1 | 0.076 | 0.074           |          |
|  SERTAD4 |  SGO1 | 0.076 |            |          |
|  TBCCD1 |  SERTAD4 | 0.076 |            |          |
|  SERTAD4 |  PPFIA3 | 0.076 |            |          |
|  ANKLE2 |  IER2 | 0.076 |            |
mutually_exclusive (P62714)        
|
|  PPP2R2C |  CCDC6 | 0.074 | 0.024           |
mutually_exclusive (P67775)        
|
|  ANKLE2 |  PPP2R2C | 0.074 | 0.034           |
mutually_exclusive (P30153)        
|
|  PABIR1 |  PPP4R1 | 0.063 | 0.082           |          |
|  ANKLE2 |  FOXC2 | 0.063 | 0.18           |          |
|  PPFIA1 |  FOXC2 | 0.063 | 0.14           |          |
|  SGO2 |  PPP4R1 | 0.063 | 0.052           |          |
|  ANKLE2 |  SERTAD4 | 0.058 |            |          |
|  SGO1 |  PPP4C | 0.05 | 0.166           |          |
|  SGO2 |  PPP2R5D | 0.049 | 0.132           |          |
|  SGO2 |  PPFIA1 | 0.048 | 0.104           |          |
|  SERTAD4 |  FECH | 0.044 |            |          |
|  FOXC1 |  IGBP1 | 0.044 | 0.102           |          |
|  IER5 |  SGO1 | 0.043 |            |          |
|  SERTAD2 |  SGO1 | 0.043 |            |          |
|  SGO2 |  SERTAD2 | 0.043 |            |          |
|  IER2 |  SGO1 | 0.043 |            |          |
|  SGO2 |  PPP2R2C | 0.042 | 0.072           |          |
|  ANKLE2 |  SGO2 | 0.034 | 0.126           |          |
|  SERTAD4 |  CCDC6 | 0.026 |            |          |
|  TBCCD1 |  IGBP1 | 0.023 |            |          |
|  ANKLE2 |  PPP2CA | 0.006 | 0.072           |          |
|  SERTAD4 |  IGBP1 | 0.006 |            |          |
Related Complexes