hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06709.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RPP40 | Ribonuclease P protein subunit p40 (RNaseP protein p40) (RNase P subunit 1) | 5 | UniProt NCBI |
| RPP14 | Ribonuclease P protein subunit p14 | 5 | UniProt NCBI |
| ENOX1 | Ecto-NOX disulfide-thiol exchanger 1 (Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase) (cCNOX) (Cell proliferation-inducing gene 38 protein) (Constitutive Ecto-NOX) (cNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] | 5 | UniProt NCBI |
| RPP21 | Ribonuclease P protein subunit p21 (RNaseP protein p21) (Ribonuclease P/MRP 21 kDa subunit) (Ribonucleoprotein V) | 5 | UniProt NCBI |
| RPP38 | Ribonuclease P protein subunit p38 (RNaseP protein p38) | 5 | UniProt NCBI |
| POP5 | Ribonuclease P/MRP protein subunit POP5 (hPop5) | 5 | UniProt NCBI |
| C18orf21 | UPF0711 protein C18orf21 (HBV X-transactivated gene 13 protein) (HBV XAg-transactivated protein 13) | 2 | UniProt NCBI |
| POP4 | Ribonuclease P protein subunit p29 (hPOP4) | 5 | UniProt NCBI |
| ENOX2 | Ecto-NOX disulfide-thiol exchanger 2 (APK1 antigen) (Cytosolic ovarian carcinoma antigen 1) (Tumor-associated hydroquinone oxidase) (tNOX) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)] | 5 | UniProt NCBI |
| RPP30 | Ribonuclease P protein subunit p30 (RNaseP protein p30) (RNase P subunit 2) | 5 | UniProt NCBI |
| RPP25 | Ribonuclease P protein subunit p25 (RNase P protein subunit p25) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:123 | 9.56478128356e-24 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | Rnase/Mrp complex |
| GO:0030681 | 7.20228030652e-21 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | multimeric ribonuclease P complex |
| GO:0033204 | 7.20228030652e-21 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ribonuclease P RNA binding |
| GO:0004526 | 2.64035394183e-20 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ribonuclease P activity |
| GO:0001682 | 2.05872402761e-19 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA 5'-leader removal |
| GO:0030677 | 2.05872402761e-19 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ribonuclease P complex |
| GO:0004549 | 4.8028121718e-19 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA-specific ribonuclease activity |
| GO:0099116 | 1.028986083e-18 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA 5'-end processing |
| GO:0034471 | 2.0124792221e-17 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ncRNA 5'-end processing |
| GO:0000966 | 3.25033405907e-17 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | RNA 5'-end processing |
| GO:0016891 | 2.49313384684e-16 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | RNA endonuclease activity, producing 5'-phosphomonoesters |
| REAC:R-HSA-6784531 | 1.00142766455e-15 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA processing in the nucleus |
| GO:1902555 | 1.25776062685e-15 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | endoribonuclease complex |
| GO:0016893 | 2.21284939385e-15 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:1905348 | 3.7497548977e-15 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | endonuclease complex |
| REAC:R-HSA-72306 | 1.39678573625e-13 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA processing |
| GO:0004521 | 1.93275539257e-13 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | RNA endonuclease activity |
| GO:0004519 | 1.0141748042e-11 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | endonuclease activity |
| GO:0004540 | 3.45120561032e-11 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | RNA nuclease activity |
| GO:0140101 | 5.97122061374e-11 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | catalytic activity, acting on a tRNA |
| GO:0008033 | 8.03703948746e-11 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA processing |
| GO:0000172 | 2.32722490539e-10 | 0.454545454545 | RPP40 RPP30 RPP25 POP5 POP4 | ribonuclease MRP complex |
| KEGG:03008 | 2.90678566958e-10 | 0.545454545455 | RPP25 RPP38 POP4 POP5 RPP40 RPP30 | Ribosome biogenesis in eukaryotes |
| GO:0004518 | 1.38845276255e-09 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | nuclease activity |
| GO:0006399 | 3.3068289056e-09 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | tRNA metabolic process |
| GO:0005732 | 1.08914331054e-07 | 0.454545454545 | RPP40 RPP30 RPP25 POP5 POP4 | sno(s)RNA-containing ribonucleoprotein complex |
| GO:0140098 | 3.41157704799e-07 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | catalytic activity, acting on RNA |
| REAC:R-HSA-6791226 | 3.65175471972e-07 | 0.545454545455 | RPP30 RPP38 RPP21 RPP14 RPP40 RPP25 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 5.058771191e-07 | 0.545454545455 | RPP30 RPP38 RPP21 RPP14 RPP40 RPP25 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 6.88911448831e-07 | 0.545454545455 | RPP30 RPP38 RPP21 RPP14 RPP40 RPP25 | rRNA processing |
| GO:0034470 | 7.92467706748e-07 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ncRNA processing |
| REAC:R-HSA-8953854 | 8.34141712255e-07 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | Metabolism of RNA |
| GO:0140640 | 1.21581805206e-05 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | catalytic activity, acting on a nucleic acid |
| GO:0034660 | 1.66759864631e-05 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ncRNA metabolic process |
| GO:0016788 | 3.68996414158e-05 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | hydrolase activity, acting on ester bonds |
| GO:1990904 | 5.1252476381e-05 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | ribonucleoprotein complex |
| GO:0005655 | 6.34131776058e-05 | 0.272727272727 | RPP40 RPP21 RPP30 | nucleolar ribonuclease P complex |
| GO:0006396 | 0.000397901123852 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | RNA processing |
| GO:0140535 | 0.000693488303304 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | intracellular protein-containing complex |
| GO:0005730 | 0.0174458136976 | 0.636363636364 | POP5 RPP38 POP4 RPP21 RPP40 RPP30 RPP14 | nucleolus |
| GO:0003723 | 0.0440585189181 | 0.727272727273 | POP5 RPP38 RPP25 POP4 RPP21 RPP40 RPP30 RPP14 | RNA binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| RPP30 | RPP14 | 1.0 | 0.568 |
| RPP40 | C18orf21 | 1.0 | 0.114 |
| RPP38 | C18orf21 | 1.0 | 0.22 |
| POP5 | C18orf21 | 1.0 | 0.236 |
| RPP30 | RPP25 | 1.0 | 0.252909090909 |
| RPP30 | POP4 | 1.0 | 0.826 |
| POP4 | RPP25 | 1.0 | 0.204 |
| RPP30 | RPP38 | 1.0 | 0.378 |
| POP5 | RPP25 | 1.0 | 0.128 |
| RPP21 | RPP38 | 1.0 | 0.16 |
| POP5 | RPP30 | 0.999 | 0.312 |
| RPP14 | C18orf21 | 0.999 | 0.112 |
| RPP40 | POP4 | 0.999 | 0.512 |
| RPP38 | RPP25 | 0.999 | 0.1 |
| RPP40 | RPP21 | 0.999 | 0.186 |
| POP5 | POP4 | 0.999 | 0.342 |
| POP5 | RPP21 | 0.999 | 0.222 |
| POP5 | RPP14 | 0.999 | 0.312 |
| RPP40 | RPP25 | 0.999 | 0.05 |
| RPP21 | POP4 | 0.999 | 0.14 |
| POP5 | RPP38 | 0.999 | 0.248 |
| POP5 | RPP40 | 0.999 | 0.22 |
| RPP14 | RPP21 | 0.999 | 0.178 |
| RPP40 | RPP14 | 0.999 | 0.756 |
| RPP21 | RPP25 | 0.999 | 0.054 |
| RPP14 | RPP38 | 0.999 | 0.578 |
| RPP30 | C18orf21 | 0.999 | 0.342 |
| RPP14 | POP4 | 0.999 | 0.31 |
| RPP30 | RPP21 | 0.999 | 0.336 |
| RPP30 | RPP40 | 0.999 | 0.626 |
| RPP38 | POP4 | 0.999 | 0.646 |
| C18orf21 | RPP25 | 0.999 | 0.12 |
| RPP14 | RPP25 | 0.999 | 0.116 |
| C18orf21 | POP4 | 0.998 | 0.206 |
| POP5 | ENOX2 | 0.996 | |
| POP5 | ENOX1 | 0.995 | 0.104 |
| RPP30 | ENOX2 | 0.989 | |
| RPP40 | RPP38 | 0.986 | 0.358 |
| ENOX1 | ENOX2 | 0.853 | |
| RPP21 | C18orf21 | 0.822 | 0.224 |
| ENOX2 | RPP40 | 0.811 | |
| ENOX2 | POP4 | 0.811 | |
| ENOX2 | RPP25 | 0.797 | |
| ENOX2 | C18orf21 | 0.79 | |
| ENOX2 | RPP14 | 0.79 | |
| ENOX2 | RPP38 | 0.78 | |
| ENOX1 | RPP21 | 0.768 | 0.092 |
| ENOX1 | C18orf21 | 0.553 | 0.11 |
| ENOX1 | RPP14 | 0.553 | 0.07 |
| ENOX1 | RPP30 | 0.488 | 0.104 |
| ENOX1 | RPP25 | 0.454 | 0.086 |
| ENOX1 | RPP38 | 0.445 | 0.058 |
| ENOX1 | RPP40 | 0.44 | 0.056 |
| ENOX1 | POP4 | 0.407 | 0.148 |
| ENOX2 | RPP21 | 0.337 |
Related Complexes