hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06750.1
Complex Portal: CPX-14632
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VLDLR | Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) | 5 | UniProt NCBI |
| SYT5 | Synaptotagmin-5 (Synaptotagmin V) (SytV) | 5 | UniProt NCBI |
| SYT1 | Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65) | 5 | UniProt NCBI |
| SYT2 | Synaptotagmin-2 (Synaptotagmin II) (SytII) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0091031 | 0.0253564028883 | 0.666666666667 | SYT5 SYT2 | cerebellum; processes in molecular layer[>=Low] |
| HPA:0090991 | 0.0420544039627 | 0.666666666667 | SYT5 SYT2 | cerebellum; molecular layer - neuropil[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SYT2 | SYT1 | 1.0 |
mutually_exclusive (O00445)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| SYT5 | SYT1 | 0.991 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| VLDLR | SYT1 | 0.983 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SYT2 | SYT5 | 0.979 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| VLDLR | SYT2 | 0.895 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| VLDLR | SYT5 | 0.299 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes