hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06762.1
Complex Portal: CPX-18117
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PKD1 | Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein) | 5 | UniProt NCBI |
| AGRN | Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)] | 5 | UniProt NCBI |
| CTBS | Di-N-acetylchitobiase (EC 3.2.1.-) | 4 | UniProt NCBI |
| EDN3 | Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:521 | 0.0499402709677 | 0.333333333333 | PKD1 | Polycystin-1-E-cadherin-beta-catenin complex |
| CORUM:6600 | 0.0499402709677 | 0.333333333333 | PKD1 | NPHP1-PKD1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PKD1 | EDN3 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| EDN3 | AGRN | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CTBS | EDN3 | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PKD1 | CTBS | 0.587 | 0.088 | bioplex3_WMM WMM_only | |
| CTBS | AGRN | 0.499 | 0.07 | bioplex3_WMM WMM_only | |
| PKD1 | AGRN | 0.433 | 0.088 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PKD1 | huMAP3_00485.1 huMAP3_03611.1 huMAP3_06762.1 huMAP3_06930.1 huMAP3_07676.1 |
| AGRN | huMAP3_06762.1 |
| CTBS | huMAP3_02359.1 huMAP3_06762.1 huMAP3_14960.1 |
| EDN3 | huMAP3_03611.1 huMAP3_06762.1 |