hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06779.1
Complex Portal: CPX-15297
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CDIN1 | CDAN1-interacting nuclease 1 (Protein HH114) | 5 | UniProt NCBI |
| IPO4 | Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4) | 5 | UniProt NCBI |
| ASF1A | Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA) | 5 | UniProt NCBI |
| NPAT | Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220) | 5 | UniProt NCBI |
| CDAN1 | Codanin-1 | 5 | UniProt NCBI |
| ASF1B | Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II) | 5 | UniProt NCBI |
| HAT1 | Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1) | 5 | UniProt NCBI |
| MMS22L | Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like) | 5 | UniProt NCBI |
| TONSL | Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1150 | 1.88219840941e-10 | 0.444444444444 | ASF1B IPO4 HAT1 ASF1A | Histone H3.3 complex |
| CORUM:1149 | 3.76336611262e-10 | 0.444444444444 | ASF1B IPO4 HAT1 ASF1A | Histone H3.1 complex |
| CORUM:6149 | 1.31072783286e-08 | 0.333333333333 | IPO4 CDAN1 ASF1A | Codanin-1-Asf1-histone H3.1-histone H4-importin-4 complex, cytosolic |
| CORUM:2235 | 0.000273361732609 | 0.222222222222 | ASF1A ASF1B | ASF1-interacting protein complex |
| CORUM:2236 | 0.000409911647195 | 0.222222222222 | ASF1A ASF1B | ASF1-histone containing complex |
| HP:0011273 | 0.0414791566521 | 0.222222222222 | CDIN1 CDAN1 | Anisocytosis |
| HP:0012132 | 0.0466491465176 | 0.222222222222 | CDIN1 CDAN1 | Erythroid hyperplasia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IPO4 | ASF1A | 0.999 | 0.05 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 | |
| IPO4 | ASF1B | 0.999 | 0.074 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| ASF1B | HAT1 | 0.999 | 0.422 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| ASF1A | CDAN1 | 0.997 | 0.114 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| ASF1A | HAT1 | 0.995 | 0.364 |
mixed_interface
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 |
| CDIN1 | ASF1A | 0.994 | 0.114 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| ASF1A | ASF1B | 0.991 | 0.136 |
mutually_exclusive (P49321)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 |
| CDAN1 | ASF1B | 0.991 | 0.088 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ASF1B | TONSL | 0.989 | 0.15 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ASF1A | TONSL | 0.984 | 0.097 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CDIN1 | ASF1B | 0.982 | 0.044 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HAT1 | NPAT | 0.969 | 0.158 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ASF1B | NPAT | 0.952 | 0.104 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ASF1B | MMS22L | 0.95 | 0.132 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TONSL | MMS22L | 0.909 | 0.452 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDIN1 | CDAN1 | 0.802 | 0.098 |
mutually_exclusive (Q9NVP2)
|
hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| TONSL | HAT1 | 0.781 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| ASF1A | NPAT | 0.717 | 0.19 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| IPO4 | TONSL | 0.656 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| IPO4 | HAT1 | 0.619 | 0.108 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| IPO4 | NPAT | 0.51 | 0.072 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| TONSL | NPAT | 0.46 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDIN1 | HAT1 | 0.44 | 0.12 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ASF1A | MMS22L | 0.411 | 0.174 | bioplex_WMM bioplex3_WMM WMM_only | |
| MMS22L | NPAT | 0.375 | 0.106 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| MMS22L | HAT1 | 0.358 | 0.166 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CDAN1 | HAT1 | 0.354 | 0.104 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| IPO4 | MMS22L | 0.263 | 0.146 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CDIN1 | TONSL | 0.234 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDAN1 | TONSL | 0.234 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only | |
| IPO4 | CDAN1 | 0.194 | 0.104 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CDAN1 | MMS22L | 0.187 | 0.194 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDIN1 | MMS22L | 0.187 | 0.126 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDIN1 | IPO4 | 0.181 | 0.07 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes