hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06806.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GYG1 | Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186) | 5 | UniProt NCBI |
| PPP1R3B | Protein phosphatase 1 regulatory subunit 3B (Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL) (Protein phosphatase 1 regulatory subunit 4) (PP1 subunit R4) (Protein phosphatase 1 subunit GL) (PTG) | 4 | UniProt NCBI |
| AMY2A | Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) | 5 | UniProt NCBI |
| GYS1 | Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1) | 5 | UniProt NCBI |
| GBE1 | 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00500 | 7.88665904961e-07 | 0.75 | GYG1 AMY2A GBE1 | Starch and sucrose metabolism |
| WP:WP5173 | 0.000198998246169 | 0.5 | GYG1 GBE1 | Disorders of galactose metabolism |
| REAC:R-HSA-3229121 | 0.000931962666506 | 0.5 | GYG1 GBE1 | Glycogen storage diseases |
| REAC:R-HSA-3322077 | 0.000931962666506 | 0.5 | GYG1 GBE1 | Glycogen synthesis |
| WP:WP500 | 0.00169541860832 | 0.5 | GYG1 GBE1 | Glycogen synthesis and degradation |
| GO:0005978 | 0.00190418300832 | 0.75 | GYG1 GBE1 PPP1R3B | glycogen biosynthetic process |
| GO:0009250 | 0.00190418300832 | 0.75 | GYG1 GBE1 PPP1R3B | glucan biosynthetic process |
| REAC:R-HSA-8982491 | 0.00282403231951 | 0.5 | GYG1 GBE1 | Glycogen metabolism |
| REAC:R-HSA-5663084 | 0.00444848198459 | 0.5 | GYG1 GBE1 | Diseases of carbohydrate metabolism |
| GO:0005977 | 0.00544401218013 | 0.75 | GYG1 GBE1 PPP1R3B | glycogen metabolic process |
| GO:0044042 | 0.00544401218013 | 0.75 | GYG1 GBE1 PPP1R3B | glucan metabolic process |
| GO:0000271 | 0.00622026610693 | 0.75 | GYG1 GBE1 PPP1R3B | polysaccharide biosynthetic process |
| GO:0006112 | 0.00847564117007 | 0.75 | GYG1 GBE1 PPP1R3B | energy reserve metabolic process |
| GO:0005975 | 0.0100596833963 | 1.0 | GYG1 GBE1 AMY2A PPP1R3B | carbohydrate metabolic process |
| GO:0005976 | 0.0137962469792 | 0.75 | GYG1 GBE1 PPP1R3B | polysaccharide metabolic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PPP1R3B | GYG1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PPP1R3B | GYS1 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AMY2A | GYG1 | 0.985 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AMY2A | GYS1 | 0.98 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GYS1 | GBE1 | 0.978 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GYG1 | GBE1 | 0.978 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GYG1 | GYS1 | 0.962 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only |
| PPP1R3B | GBE1 | 0.002 | bioplex3_HCT116 WMM_only | |
| AMY2A | GBE1 | 0.002 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes