hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06824.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADD2 | Beta-adducin (Erythrocyte adducin subunit beta) | 5 | UniProt NCBI |
| GBP2 | Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2) | 5 | UniProt NCBI |
| ANKRD29 | Ankyrin repeat domain-containing protein 29 | 4 | UniProt NCBI |
| ADD3 | Gamma-adducin (Adducin-like protein 70) | 5 | UniProt NCBI |
| ADD1 | Alpha-adducin (Erythrocyte adducin subunit alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5223345 | 3.55148388129e-06 | 0.6 | ADD1 ADD2 ADD3 | Miscellaneous transport and binding events |
| GO:0051016 | 0.00147736290187 | 0.6 | ADD1 ADD2 ADD3 | barbed-end actin filament capping |
| GO:0051693 | 0.00147736290187 | 0.6 | ADD1 ADD2 ADD3 | actin filament capping |
| GO:0030835 | 0.00220577099344 | 0.6 | ADD1 ADD2 ADD3 | negative regulation of actin filament depolymerization |
| GO:0030834 | 0.00475337188383 | 0.6 | ADD1 ADD2 ADD3 | regulation of actin filament depolymerization |
| GO:0030042 | 0.00744248347584 | 0.6 | ADD1 ADD2 ADD3 | actin filament depolymerization |
| GO:0030837 | 0.00744248347584 | 0.6 | ADD1 ADD2 ADD3 | negative regulation of actin filament polymerization |
| GO:1901880 | 0.0135806930791 | 0.6 | ADD1 ADD2 ADD3 | negative regulation of protein depolymerization |
| GO:0032272 | 0.016548216138 | 0.6 | ADD1 ADD2 ADD3 | negative regulation of protein polymerization |
| GO:0043242 | 0.0250826699056 | 0.6 | ADD1 ADD2 ADD3 | negative regulation of protein-containing complex disassembly |
| GO:1901879 | 0.0264997162634 | 0.6 | ADD1 ADD2 ADD3 | regulation of protein depolymerization |
| GO:0043254 | 0.0368664091126 | 0.8 | ADD1 ADD3 ADD2 GBP2 | regulation of protein-containing complex assembly |
| HPA:0461472 | 0.0423206374997 | 0.6 | ADD1 GBP2 ADD3 | skin 1; lymphocytes[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ADD1 | ADD2 | 1.0 | 0.352 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| ANKRD29 | ADD2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ANKRD29 | ADD3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ADD3 | ADD1 | 0.999 | 0.558 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| ANKRD29 | ADD1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ADD3 | ADD2 | 0.999 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| ADD3 | GBP2 | 0.999 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ADD1 | GBP2 | 0.989 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes