hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06859.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPRED2 | Sprouty-related, EVH1 domain-containing protein 2 (Spred-2) | 5 | UniProt NCBI |
| ZDHHC17 | Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) | 5 | UniProt NCBI |
| ZDHHC13 | Palmitoyltransferase ZDHHC13 (EC 2.3.1.225) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin-interacting protein HIP3RP) (Putative MAPK-activating protein PM03) (Putative NF-kappa-B-activating protein 209) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) | 5 | UniProt NCBI |
| SPRY4 | Protein sprouty homolog 4 (Spry-4) | 5 | UniProt NCBI |
| DNAJC5B | DnaJ homolog subfamily C member 5B (Cysteine-string protein isoform beta) (CSP-beta) | 3 | UniProt NCBI |
| AOPEP | Aminopeptidase O (AP-O) (EC 3.4.11.-) | 5 | UniProt NCBI |
| PLSCR4 | Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4) (Cell growth-inhibiting gene 43 protein) (TRA1) | 5 | UniProt NCBI |
| SPRY2 | Protein sprouty homolog 2 (Spry-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5654736 | 0.0274432906045 | 0.25 | SPRY2 SPRED2 | Signaling by FGFR1 |
| GO:1902747 | 0.0393180950424 | 0.25 | SPRY2 SPRED2 | negative regulation of lens fiber cell differentiation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PLSCR4 | ZDHHC17 | 0.989 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | |
| ZDHHC17 | SPRED2 | 0.984 | 0.154 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ZDHHC17 | AOPEP | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZDHHC13 | SPRY4 | 0.971 | 0.076 | bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| ZDHHC17 | SPRY4 | 0.969 | 0.118 | bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| ZDHHC13 | DNAJC5B | 0.967 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZDHHC17 | DNAJC5B | 0.967 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PLSCR4 | ZDHHC13 | 0.966 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | |
| ZDHHC17 | ZDHHC13 | 0.963 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only |
| ZDHHC17 | SPRY2 | 0.96 | 0.106 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ZDHHC13 | SPRED2 | 0.952 | 0.138 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ZDHHC13 | SPRY2 | 0.927 | 0.154 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| SPRY4 | SPRY2 | 0.131 | 0.192 | bioplex3_WMM WMM_only |
Related Complexes