hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06872.1
Complex Portal: CPX-18713
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDHA6 | Protocadherin alpha-6 (PCDH-alpha-6) | 5 | UniProt NCBI |
| PCDHA13 | Protocadherin alpha-13 (PCDH-alpha-13) | 4 | UniProt NCBI |
| PCDHA8 | Protocadherin alpha-8 (PCDH-alpha-8) | 4 | UniProt NCBI |
| PCDHA12 | Protocadherin alpha-12 (PCDH-alpha-12) | 4 | UniProt NCBI |
| PCDHA2 | Protocadherin alpha-2 (PCDH-alpha-2) | 5 | UniProt NCBI |
| PCDHA4 | Protocadherin alpha-4 (PCDH-alpha-4) | 5 | UniProt NCBI |
| PCDHA7 | Protocadherin alpha-7 (PCDH-alpha-7) | 5 | UniProt NCBI |
| PCDHA10 | Protocadherin alpha-10 (PCDH-alpha-10) | 5 | UniProt NCBI |
| PCDHA1 | Protocadherin alpha-1 (PCDH-alpha-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| TF:M06624 | 9.06118620852e-15 | 0.888888888889 | PCDHA8 PCDHA12 PCDHA4 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: ZNF2; motif: NSATCGATCCGA |
| TF:M00162_1 | 5.17492259592e-11 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: Oct-1; motif: CWNAWTKWSATRYN; match class: 1 |
| MIRNA:hsa-miR-221-3p | 8.293373019e-11 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | hsa-miR-221-3p |
| MIRNA:hsa-miR-181a-5p | 1.67442969378e-09 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | hsa-miR-181a-5p |
| GO:0007155 | 7.26226289013e-07 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | cell adhesion |
| TF:M07050 | 2.46819300672e-05 | 0.777777777778 | PCDHA8 PCDHA7 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA12 | Factor: MITF; motif: NNCACATGNNN |
| TF:M10991 | 0.000685368997201 | 0.888888888889 | PCDHA7 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA12 | Factor: lmx1b; motif: CTCGTTAA |
| TF:M10758 | 0.000858868765659 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: HOXB1; motif: NTCRTTAN |
| TF:M11002 | 0.000901317459666 | 0.888888888889 | PCDHA7 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA12 | Factor: LHX5; motif: NTCGTTAN |
| TF:M10683 | 0.00102005546199 | 0.888888888889 | PCDHA7 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA12 | Factor: HOXB7; motif: GTCRTTAN |
| TF:M06531 | 0.00136896158018 | 0.555555555556 | PCDHA4 PCDHA6 PCDHA2 PCDHA12 PCDHA8 | Factor: ZNF555; motif: NCRWGTTTGKCC |
| TF:M11633_1 | 0.00161055483817 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: Sox-10; motif: AACAATGGNCCATTGTT; match class: 1 |
| TF:M10755 | 0.0017651688115 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: hoxd1; motif: NTCRTTAN |
| TF:M10783 | 0.00319109083887 | 0.888888888889 | PCDHA7 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA12 | Factor: hoxa9; motif: RTCGTWAANN |
| TF:M07459 | 0.00328348913794 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: HSF1; motif: GAANNTTCTNGN |
| TF:M00162 | 0.00334756225525 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: Oct-1; motif: CWNAWTKWSATRYN |
| TF:M11633 | 0.00637613408666 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: Sox-10; motif: AACAATGGNCCATTGTT |
| TF:M12706 | 0.0066211719164 | 0.888888888889 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA6 PCDHA13 PCDHA7 | Factor: ZNF450; motif: NNNAGGTCCTGGMAGNK |
| TF:M10801 | 0.0096503461104 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: HOXA10; motif: NRTCGTAAANN |
| TF:M10575 | 0.011257213865 | 0.888888888889 | PCDHA7 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA12 | Factor: Gbx2; motif: NTCRTTAN |
| TF:M10686 | 0.014965966958 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: HOXB7; motif: GTCRTTAN |
| TF:M10729 | 0.0206331218445 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: HOXC-8; motif: RTCRTTAN |
| TF:M11632_1 | 0.0389848516762 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: Sox-10; motif: AACAATRGNCYATTGTT; match class: 1 |
| TF:M10116 | 0.0397617160839 | 0.777777777778 | PCDHA8 PCDHA7 PCDHA6 PCDHA10 PCDHA2 PCDHA13 PCDHA12 | Factor: ZID; motif: GGNGMTGGAGCCN |
| TF:M10723 | 0.0413373789707 | 1.0 | PCDHA8 PCDHA12 PCDHA4 PCDHA10 PCDHA2 PCDHA1 PCDHA6 PCDHA13 PCDHA7 | Factor: HOXD8; motif: RTCRTTAN |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDHA8 | PCDHA2 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA8 | PCDHA7 | 0.998 |
mutually_exclusive (Q9Y5H9)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA8 | PCDHA12 | 0.998 |
mutually_exclusive (Q9UN74)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA4 | PCDHA1 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PCDHA8 | PCDHA1 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA8 | PCDHA10 | 0.996 |
mutually_exclusive (Q9Y5I0)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHA7 | PCDHA10 | 0.995 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHA2 | PCDHA10 | 0.995 |
mutually_exclusive (Q9UN72)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHA4 | PCDHA10 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHA12 | PCDHA10 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHA6 | PCDHA10 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHA13 | PCDHA10 | 0.993 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHA2 | PCDHA7 | 0.99 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA4 | PCDHA7 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHA7 | PCDHA12 | 0.988 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDHA4 | PCDHA12 | 0.982 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHA13 | PCDHA8 | 0.977 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA8 | PCDHA6 | 0.975 |
mutually_exclusive (Q9Y5H8)
structurally_consistent (dimer) |
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA4 | PCDHA8 | 0.975 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHA2 | PCDHA1 | 0.904 |
mutually_exclusive (Q9Y5H6)
|
bioplex3_WMM WMM_only | |
| PCDHA13 | PCDHA1 | 0.902 |
mutually_exclusive (Q9Y5H6)
|
bioplex3_WMM WMM_only | |
| PCDHA13 | PCDHA6 | 0.843 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA13 | PCDHA2 | 0.835 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA1 | PCDHA12 | 0.824 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHA13 | PCDHA12 | 0.823 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA4 | PCDHA13 | 0.823 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA13 | PCDHA7 | 0.823 |
mutually_exclusive (Q9Y5I2)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA6 | PCDHA12 | 0.814 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA6 | PCDHA1 | 0.814 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHA7 | PCDHA6 | 0.814 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHA4 | PCDHA6 | 0.814 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA4 | PCDHA2 | 0.814 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA2 | PCDHA6 | 0.812 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA2 | PCDHA12 | 0.786 |
mutually_exclusive (Q9Y5H6)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHA7 | PCDHA1 | 0.782 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHA1 | PCDHA10 | 0.214 | bioplex3_WMM WMM_only |
Related Complexes