hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06889.1
Complex Portal: CPX-22080
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFMBT1 | Scm-like with four MBT domains protein 1 (hSFMBT) (Renal ubiquitous protein 1) | 5 | UniProt NCBI |
| HDAC1 | Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) | 5 | UniProt NCBI |
| CCDC71 | Coiled-coil domain-containing protein 71 | 2 | UniProt NCBI |
| PHF21B | PHD finger protein 21B | 3 | UniProt NCBI |
| CASP8AP2 | CASP8-associated protein 2 (FLICE-associated huge protein) | 5 | UniProt NCBI |
| PWWP2B | PWWP domain-containing protein 2B | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:626 | 0.00133016076778 | 0.333333333333 | HDAC1 PHF21B | LSD1 complex |
| KEGG:03083 | 0.0232178892038 | 0.333333333333 | SFMBT1 HDAC1 | Polycomb repressive complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PWWP2B | HDAC1 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| SFMBT1 | HDAC1 | 0.984 | 0.17106122449 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HDAC1 | CASP8AP2 | 0.977 | 0.256 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| HDAC1 | PHF21B | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CCDC71 | HDAC1 | 0.967 | 0.118 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
| PHF21B | CASP8AP2 | 0.497 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SFMBT1 | PHF21B | 0.406 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PWWP2B | CCDC71 | 0.359 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CCDC71 | PHF21B | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PWWP2B | CASP8AP2 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PWWP2B | PHF21B | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CCDC71 | CASP8AP2 | 0.333 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only | |
| CCDC71 | SFMBT1 | 0.303 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| SFMBT1 | CASP8AP2 | 0.265 | 0.188 | bioplex_WMM bioplex3_WMM WMM_only | |
| PWWP2B | SFMBT1 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes