hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06916.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KIF1A | Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104) | 5 | UniProt NCBI |
| KIF15 | Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62) | 5 | UniProt NCBI |
| KIF13B | Kinesin-like protein KIF13B (Kinesin-like protein GAKIN) | 5 | UniProt NCBI |
| KIF1B | Kinesin-like protein KIF1B (Klp) | 5 | UniProt NCBI |
| KIFBP | KIF-binding protein (KIF1-binding protein) (Kinesin family binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-983189 | 1.34717770914e-07 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Kinesins |
| REAC:R-HSA-6811434 | 1.24109632959e-06 | 0.8 | KIF13B KIF1B KIF1A KIF15 | COPI-dependent Golgi-to-ER retrograde traffic |
| KEGG:04814 | 3.50082479815e-06 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Motor proteins |
| REAC:R-HSA-8856688 | 4.24686934885e-06 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Golgi-to-ER retrograde transport |
| GO:0005871 | 8.67338862712e-06 | 0.8 | KIF13B KIF1B KIF1A KIF15 | kinesin complex |
| REAC:R-HSA-983231 | 1.03179988059e-05 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811442 | 2.36864607463e-05 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0003777 | 3.5523826943e-05 | 0.8 | KIF13B KIF1B KIF1A KIF15 | microtubule motor activity |
| GO:0003774 | 0.000319733015871 | 0.8 | KIF13B KIF1B KIF1A KIF15 | cytoskeletal motor activity |
| GO:0016887 | 0.00118663084114 | 0.8 | KIF13B KIF1B KIF1A KIF15 | ATP hydrolysis activity |
| GO:0005875 | 0.00118663084114 | 0.8 | KIF13B KIF1B KIF1A KIF15 | microtubule associated complex |
| REAC:R-HSA-109582 | 0.00129857214677 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Hemostasis |
| REAC:R-HSA-199991 | 0.00183945180572 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.00228321498701 | 0.8 | KIF13B KIF1B KIF1A KIF15 | Vesicle-mediated transport |
| GO:0008017 | 0.0100477300178 | 0.8 | KIF13B KIF1B KIF1A KIF15 | microtubule binding |
| GO:0007017 | 0.0119069088956 | 1.0 | KIF13B KIFBP KIF1B KIF1A KIF15 | microtubule-based process |
| GO:0008092 | 0.0133485794118 | 1.0 | KIF13B KIFBP KIF1B KIF1A KIF15 | cytoskeletal protein binding |
| HP:0001069 | 0.0191806250585 | 0.4 | KIF1B KIF1A | Episodic hyperhidrosis |
| GO:0007018 | 0.0284935982879 | 0.8 | KIF13B KIF1B KIF1A KIF15 | microtubule-based movement |
| GO:0005874 | 0.0289172689799 | 0.8 | KIF13B KIF1B KIF1A KIF15 | microtubule |
| GO:0015631 | 0.0405744022835 | 0.8 | KIF13B KIF1B KIF1A KIF15 | tubulin binding |
| HP:0003380 | 0.0497672375822 | 0.4 | KIF1B KIF1A | Decreased number of peripheral myelinated nerve fibers |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KIF1B | KIF1A | 1.0 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| KIF13B | KIFBP | 0.999 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| KIF15 | KIFBP | 0.995 | 0.054 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| KIF1A | KIFBP | 0.967 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM | |
| KIF1B | KIFBP | 0.96 | 0.11 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| KIF15 | KIF13B | 0.788 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only |
| KIF1B | KIF15 | 0.715 | 0.106 | bioplex_WMM bioplex3_WMM fraction |
| KIF1B | KIF13B | 0.507 | 0.098 | youn () bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| KIF1A | KIF15 | 0.124 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| KIF1A | KIF13B | 0.049 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes