hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06970.1
Complex Portal: CPX-21290
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GCAT | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) | 5 | UniProt NCBI |
| ACSL1 | Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Acyl-CoA synthetase 1) (ACS1) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Long-chain fatty acid-CoA ligase 2) (Palmitoyl-CoA ligase 1) (Palmitoyl-CoA ligase 2) (Phytanate--CoA ligase) (EC 6.2.1.24) | 5 | UniProt NCBI |
| PGM3 | Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3) | 5 | UniProt NCBI |
| ITM2C | Integral membrane protein 2C (Cerebral protein 14) (Transmembrane protein BRI3) [Cleaved into: CT-BRI3] | 5 | UniProt NCBI |
| EARS2 | Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.24) (Glutamate--tRNA(Gln) ligase EARS2, mitochondrial) (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (Mitochondrial glutamyl-tRNA synthetase) (mtGluRS) | 5 | UniProt NCBI |
| RO60 | RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Ro60 autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2) | 5 | UniProt NCBI |
| RUSF1 | RUS family member 1 | 5 | UniProt NCBI |
| PEX3 | Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04146 | 0.0203999615702 | 0.285714285714 | ACSL1 PEX3 | Peroxisome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RUSF1 | ITM2C | 0.996 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| RUSF1 | EARS2 | 0.994 | 0.038 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt_WMM WMM_only | |
| RUSF1 | GCAT | 0.989 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| GCAT | ACSL1 | 0.988 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| PEX3 | RUSF1 | 0.985 | 0.036 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| GCAT | EARS2 | 0.983 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| ITM2C | GCAT | 0.982 | 0.026 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| PGM3 | ACSL1 | 0.98 | 0.11 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| RO60 | GCAT | 0.979 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| ITM2C | ACSL1 | 0.979 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| RO60 | ACSL1 | 0.979 | 0.066 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| RUSF1 | ACSL1 | 0.978 | 0.034 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| RUSF1 | PGM3 | 0.962 | 0.048 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| RUSF1 | RO60 | 0.96 | 0.03 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PEX3 | ACSL1 | 0.959 | 0.042 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PEX3 | GCAT | 0.958 | 0.03 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| PEX3 | ITM2C | 0.954 | 0.022 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| PEX3 | RO60 | 0.952 | 0.038 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| RO60 | EARS2 | 0.949 | 0.046 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM | |
| ITM2C | EARS2 | 0.949 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| EARS2 | ACSL1 | 0.938 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| PEX3 | PGM3 | 0.931 | 0.016 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PEX3 | EARS2 | 0.928 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| RO60 | PGM3 | 0.911 | 0.116 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| PGM3 | EARS2 | 0.895 | 0.032 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM | |
| ITM2C | PGM3 | 0.882 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| ITM2C | RO60 | 0.869 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| PGM3 | GCAT | 0.822 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
Related Complexes