hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06993.1
Complex Portal: CPX-11551
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RREB1 | Ras-responsive element-binding protein 1 (RREB-1) (Finger protein in nuclear bodies) (Raf-responsive zinc finger protein LZ321) (Zinc finger motif enhancer-binding protein 1) (Zep-1) | 5 | UniProt NCBI |
| CTBP1 | C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) | 5 | UniProt NCBI |
| ZEB2 | Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b) | 5 | UniProt NCBI |
| ZNF536 | Zinc finger protein 536 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:642 | 4.76749342231e-07 | 0.75 | RREB1 ZEB2 CTBP1 | CtBP complex |
| CORUM:626 | 0.00039944903428 | 0.5 | RREB1 CTBP1 | LSD1 complex |
| HP:0001166 | 0.00103738630957 | 0.75 | RREB1 ZEB2 CTBP1 | Arachnodactyly |
| HP:0001238 | 0.00186400024712 | 0.75 | RREB1 ZEB2 CTBP1 | Slender finger |
| HP:0009918 | 0.00634372129255 | 0.5 | CTBP1 ZEB2 | Ectopia pupillae |
| HP:0000322 | 0.00881998427789 | 0.75 | RREB1 ZEB2 CTBP1 | Short philtrum |
| HP:0100807 | 0.0135364936749 | 0.75 | RREB1 ZEB2 CTBP1 | Long fingers |
| HP:0000388 | 0.0183300819535 | 0.75 | RREB1 ZEB2 CTBP1 | Otitis media |
| HP:0001654 | 0.0215165706943 | 0.75 | RREB1 ZEB2 CTBP1 | Abnormal heart valve morphology |
| HP:0000047 | 0.0243605289659 | 0.75 | RREB1 ZEB2 CTBP1 | Hypospadias |
| HP:0100627 | 0.0289490607956 | 0.75 | RREB1 ZEB2 CTBP1 | Displacement of the urethral meatus |
| HP:0032076 | 0.0292052421452 | 0.75 | RREB1 ZEB2 CTBP1 | Abnormal male urethral meatus morphology |
| HP:0002607 | 0.0329787201379 | 0.5 | RREB1 ZEB2 | Bowel incontinence |
| WP:WP5097 | 0.0373138951921 | 0.25 | ZEB2 | CCL18 signaling pathway |
| HP:0012700 | 0.0424493051949 | 0.5 | RREB1 ZEB2 | Abnormal large intestine physiology |
| HP:0000008 | 0.0467645338244 | 0.75 | RREB1 ZEB2 CTBP1 | Abnormal morphology of female internal genitalia |
| HP:0000795 | 0.0471163420483 | 0.75 | RREB1 ZEB2 CTBP1 | Abnormality of the urethra |
| CORUM:6477 | 0.049938562206 | 0.25 | ZEB2 | ZEB2-KDM1A complex |
| HP:0008056 | 0.0499940694024 | 0.75 | RREB1 ZEB2 CTBP1 | Aplasia/Hypoplasia affecting the eye |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CTBP1 | RREB1 | 0.983 | 0.152 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| ZNF536 | CTBP1 | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| ZEB2 | CTBP1 | 0.956 | 0.108 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| ZNF536 | ZEB2 | 0.587 | 0.116 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZEB2 | RREB1 | 0.57 | 0.052 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF536 | RREB1 | 0.505 | 0.07 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes