hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06999.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPNS1 | Protein spinster homolog 1 (HSpin1) (SPNS1) (Spinster-like protein 1) | 5 | UniProt NCBI |
| IPO13 | Importin-13 (Imp13) (Karyopherin-13) (Kap13) (Ran-binding protein 13) (RanBP13) | 5 | UniProt NCBI |
| ICMT | Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT) | 5 | UniProt NCBI |
| ALG1 | Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) (Asparagine-linked glycosylation protein 1 homolog) (Beta-1,4-mannosyltransferase) (GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase) (GDP-mannose-dolichol diphosphochitobiose mannosyltransferase) (Mannosyltransferase-1) (MT-1) (hMat-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4299 | 0.0373138951921 | 0.25 | ICMT | Lamin A processing pathway |
| REAC:R-HSA-4549380 | 0.0499436884912 | 0.25 | ALG1 | Defective ALG1 causes CDG-1k |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SPNS1 | ICMT | 0.983 | 0.118 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| IPO13 | ALG1 | 0.975 | 0.052 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| ICMT | ALG1 | 0.974 | 0.058 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| IPO13 | ICMT | 0.97 | 0.034 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| SPNS1 | ALG1 | 0.924 | 0.052 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| IPO13 | SPNS1 | 0.819 | 0.064 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
Related Complexes