hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07011.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] | 5 | UniProt NCBI |
| CIAO1 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39) | 5 | UniProt NCBI |
| CIAO2B | Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5495 | 1.02521027753e-05 | 0.666666666667 | CIAO1 CIAO2B | CIA targeting (MIP18, CIAO1, MMS19) complex |
| CORUM:6897 | 1.02521027753e-05 | 0.666666666667 | CIAO1 CIAO2B | CIA2B-CIA1-MMS19 complex |
| CORUM:6896 | 2.05032700758e-05 | 0.666666666667 | CIAO1 CIAO2B | MMS19 complex |
| CORUM:6895 | 3.41705576683e-05 | 0.666666666667 | CIAO1 CIAO2B | MMXD complex |
| WP:WP5221 | 0.00033946652894 | 0.666666666667 | CIAO1 CIAO2B | 2q11 2 copy number variation syndrome |
| REAC:R-HSA-2564830 | 0.000531572756485 | 0.666666666667 | CIAO1 CIAO2B | Cytosolic iron-sulfur cluster assembly |
| GO:0071817 | 0.0140440992017 | 0.666666666667 | CIAO1 CIAO2B | MMXD complex |
| GO:0097361 | 0.0140440992017 | 0.666666666667 | CIAO1 CIAO2B | CIA complex |
| CORUM:7223 | 0.0499402709677 | 0.333333333333 | CIAO2B | MMS19-FAM96B complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CIAO1 | CIAO2B | 1.0 | 0.766 | hein_WMM bioplex_WMM Guru bioplex3_WMM boldt youn_WMM fraction boldt_WMM |
| DNA2 | CIAO2B | 0.992 | 0.11 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM |
| DNA2 | CIAO1 | 0.966 | 0.222 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 boldt_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| DNA2 | huMAP3_07011.1 |
| CIAO1 | huMAP3_07011.1 huMAP3_07852.1 huMAP3_08582.1 huMAP3_09042.1 huMAP3_10534.1 huMAP3_11232.1 |
| CIAO2B | huMAP3_07011.1 huMAP3_07170.1 huMAP3_07379.1 huMAP3_08439.1 huMAP3_09042.1 huMAP3_09592.1 |