hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07045.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RHOA | Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12) | 5 | UniProt NCBI |
| RAP1GDS1 | Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein) | 5 | UniProt NCBI |
| RHOC | Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9) | 5 | UniProt NCBI |
| RAP2C | Ras-related protein Rap-2c (EC 3.6.5.2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5666185 | 0.000368856835097 | 0.5 | RHOA RHOC | RHO GTPases Activate Rhotekin and Rhophilins |
| REAC:R-HSA-5627117 | 0.00175047124894 | 0.5 | RHOA RHOC | RHO GTPases Activate ROCKs |
| REAC:R-HSA-5625900 | 0.00175047124894 | 0.5 | RHOA RHOC | RHO GTPases activate CIT |
| REAC:R-HSA-416572 | 0.00175047124894 | 0.5 | RHOA RHOC | Sema4D induced cell migration and growth-cone collapse |
| REAC:R-HSA-400685 | 0.00258893271292 | 0.5 | RHOA RHOC | Sema4D in semaphorin signaling |
| GO:1902766 | 0.0028092043205 | 0.5 | RHOA RHOC | skeletal muscle satellite cell migration |
| WP:WP2431 | 0.0101461159505 | 0.5 | RHOA RHOC | Spinal cord injury |
| WP:WP4217 | 0.0168573248614 | 0.5 | RHOA RHOC | Ebola virus infection in host |
| REAC:R-HSA-373755 | 0.0174510452107 | 0.5 | RHOA RHOC | Semaphorin interactions |
| REAC:R-HSA-416482 | 0.019281632575 | 0.5 | RHOA RHOC | G alpha (12/13) signalling events |
| REAC:R-HSA-9013106 | 0.0212029570934 | 0.5 | RHOA RHOC | RHOC GTPase cycle |
| KEGG:04530 | 0.0237566589162 | 0.5 | RAP2C RHOA | Tight junction |
| REAC:R-HSA-5625740 | 0.0329793636325 | 0.5 | RHOA RHOC | RHO GTPases activate PKNs |
| CORUM:553 | 0.049938562206 | 0.25 | RHOA | RHOA-IP3R-TRPC1 complex |
| CORUM:816 | 0.049938562206 | 0.25 | RHOA | MRIP-RHOA complex |
| CORUM:3153 | 0.049938562206 | 0.25 | RHOA | GNAQ-GEFT-RHOA complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RHOA | RAP1GDS1 | 0.991 | 0.387095238095 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| RHOC | RHOA | 0.989 | 0.838 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RHOC | RAP1GDS1 | 0.975 | 0.166 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOA | RAP2C | 0.958 | 0.226684931507 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RAP1GDS1 | RAP2C | 0.91 | 0.042 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOC | RAP2C | 0.138 | 0.188294117647 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes