hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
RHOA	Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)	5	UniProt NCBI
RAP1GDS1	Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)	5	UniProt NCBI
RHOC	Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)	5	UniProt NCBI
RAP2C	Ras-related protein Rap-2c (EC 3.6.5.2)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5666185	0.000368856835097	0.5	RHOA RHOC	RHO GTPases Activate Rhotekin and Rhophilins
REAC:R-HSA-5627117	0.00175047124894	0.5	RHOA RHOC	RHO GTPases Activate ROCKs
REAC:R-HSA-5625900	0.00175047124894	0.5	RHOA RHOC	RHO GTPases activate CIT
REAC:R-HSA-416572	0.00175047124894	0.5	RHOA RHOC	Sema4D induced cell migration and growth-cone collapse
REAC:R-HSA-400685	0.00258893271292	0.5	RHOA RHOC	Sema4D in semaphorin signaling
GO:1902766	0.0028092043205	0.5	RHOA RHOC	skeletal muscle satellite cell migration
WP:WP2431	0.0101461159505	0.5	RHOA RHOC	Spinal cord injury
WP:WP4217	0.0168573248614	0.5	RHOA RHOC	Ebola virus infection in host
REAC:R-HSA-373755	0.0174510452107	0.5	RHOA RHOC	Semaphorin interactions
REAC:R-HSA-416482	0.019281632575	0.5	RHOA RHOC	G alpha (12/13) signalling events
REAC:R-HSA-9013106	0.0212029570934	0.5	RHOA RHOC	RHOC GTPase cycle
KEGG:04530	0.0237566589162	0.5	RHOA RAP2C	Tight junction
REAC:R-HSA-5625740	0.0329793636325	0.5	RHOA RHOC	RHO GTPases activate PKNs
CORUM:553	0.049938562206	0.25	RHOA	RHOA-IP3R-TRPC1 complex
CORUM:816	0.049938562206	0.25	RHOA	MRIP-RHOA complex
CORUM:3153	0.049938562206	0.25	RHOA	GNAQ-GEFT-RHOA complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
RHOA	RAP1GDS1	0.991	0.387095238095	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
RHOC	RHOA	0.989	0.838	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
RHOC	RAP1GDS1	0.975	0.166		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
RHOA	RAP2C	0.958	0.226684931507		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
RAP1GDS1	RAP2C	0.91	0.042		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
RHOC	RAP2C	0.138	0.188294117647		bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only

Genename	Complexes
RHOA	huMAP3_00059.1 huMAP3_00887.1 huMAP3_02387.1 huMAP3_06217.1 huMAP3_06483.1 huMAP3_07045.1 huMAP3_07178.1 huMAP3_13206.1
RAP1GDS1	huMAP3_00059.1 huMAP3_02387.1 huMAP3_04665.1 huMAP3_06217.1 huMAP3_07045.1 huMAP3_07178.1 huMAP3_09529.1 huMAP3_10215.1 huMAP3_11851.1 huMAP3_12712.1
RHOC	huMAP3_00059.1 huMAP3_00887.1 huMAP3_07045.1 huMAP3_07178.1 huMAP3_07311.1 huMAP3_09180.1 huMAP3_09752.1 huMAP3_11861.1 huMAP3_11952.1
RAP2C	huMAP3_03804.1 huMAP3_06179.1 huMAP3_06512.1 huMAP3_07045.1 huMAP3_07836.1 huMAP3_09165.1 huMAP3_11118.1