hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07055.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HNRNPF | Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed] | 5 | UniProt NCBI |
| HNRNPH1 | Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] | 5 | UniProt NCBI |
| HNRNPH2 | Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1287 | 3.41752350426e-06 | 0.666666666667 | HNRNPH1 HNRNPF | HNRPF-HNRPH1 complex |
| CORUM:1288 | 1.02521027753e-05 | 0.666666666667 | HNRNPH1 HNRNPF | DCS complex (PTBP1, PTBP2, HNRPH1, HNRPF) |
| REAC:R-HSA-72163 | 0.000622120634792 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.000689757414765 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.00158225905908 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | Processing of Capped Intron-Containing Pre-mRNA |
| REAC:R-HSA-6803529 | 0.00188000535098 | 0.666666666667 | HNRNPH1 HNRNPF | FGFR2 alternative splicing |
| WP:WP3584 | 0.00199965110325 | 0.666666666667 | HNRNPH1 HNRNPF | MECP2 and associated Rett syndrome |
| HPA:0490693 | 0.00391682031202 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | smooth muscle; smooth muscle cells[High] |
| HPA:0570783 | 0.0059487071562 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | testis; preleptotene spermatocytes[High] |
| HPA:0100123 | 0.00681655925187 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | cerebral cortex; glial cells[High] |
| HPA:0461423 | 0.00704427967728 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; eccrine glands[High] |
| WP:WP411 | 0.00831500934109 | 0.666666666667 | HNRNPH1 HNRNPH2 | mRNA processing |
| HPA:0351183 | 0.00883339682218 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | pancreas; pancreatic endocrine cells[High] |
| HPA:0130203 | 0.00991771548705 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | colon; endothelial cells[High] |
| CORUM:1181 | 0.00996545878074 | 0.666666666667 | HNRNPH1 HNRNPF | C complex spliceosome |
| HPA:0270353 | 0.00999560303918 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | kidney; cells in glomeruli[High] |
| REAC:R-HSA-5654738 | 0.0101009261622 | 0.666666666667 | HNRNPH1 HNRNPF | Signaling by FGFR2 |
| HPA:0130243 | 0.0103511455105 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | colon; peripheral nerve/ganglion[High] |
| HPA:0440343 | 0.0104312831454 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | skeletal muscle; myocytes[High] |
| REAC:R-HSA-190236 | 0.0128584085686 | 0.666666666667 | HNRNPH1 HNRNPF | Signaling by FGFR |
| HPA:0471493 | 0.0144360249621 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[High] |
| HPA:0461493 | 0.0163771345036 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[High] |
| HPA:0460673 | 0.0169594584426 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | skin 1; melanocytes[High] |
| HPA:0630223 | 0.0194009113254 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | cervix; squamous epithelial cells[High] |
| HPA:0080133 | 0.0230059154439 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | caudate; neuronal cells[High] |
| REAC:R-HSA-8953854 | 0.0247774527734 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | Metabolism of RNA |
| HPA:0330223 | 0.0265048582464 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | oral mucosa; squamous epithelial cells[High] |
| HPA:0461422 | 0.0302328294218 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; eccrine glands[>=Medium] |
| HPA:0461492 | 0.0316049848456 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[>=Medium] |
| HPA:0471492 | 0.0323023843332 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[>=Medium] |
| HPA:0250133 | 0.0339994352931 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | hippocampus; neuronal cells[High] |
| HP:0001211 | 0.0368991311611 | 0.666666666667 | HNRNPH1 HNRNPH2 | Abnormal fingertip morphology |
| HPA:0461413 | 0.037395322848 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; cells in spinous layer[High] |
| HPA:0500702 | 0.0401673126926 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | soft tissue 1; peripheral nerve[>=Medium] |
| HPA:0390053 | 0.040266084773 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | prostate; glandular cells[High] |
| HPA:0170053 | 0.0406627923068 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | endometrium 2; glandular cells[High] |
| HPA:0461463 | 0.0412590843677 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; langerhans cells[High] |
| HPA:0050053 | 0.0436171192214 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | breast; glandular cells[High] |
| HPA:0570782 | 0.0440355061936 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | testis; preleptotene spermatocytes[>=Medium] |
| HPA:0570813 | 0.0443510461782 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | testis; spermatogonia cells[High] |
| HPA:0040083 | 0.0485912095421 | 1.0 | HNRNPH1 HNRNPF HNRNPH2 | bone marrow; hematopoietic cells[High] |
| HPA:0380203 | 0.0491179252569 | 0.666666666667 | HNRNPH1 HNRNPH2 | placenta; endothelial cells[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HNRNPF | HNRNPH1 | 0.996 | 0.93 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM fraction boldt_WMM treiber_WMM |
| HNRNPH1 | HNRNPH2 | 0.992 | 0.626 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| HNRNPF | HNRNPH2 | 0.986 | 0.576 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM |
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