hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07074.1
Complex Portal: CPX-14885
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ICOSLG | ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275) | 5 | UniProt NCBI |
| CYP26B1 | Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 26A2) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2) (Retinoic acid-metabolizing cytochrome) | 5 | UniProt NCBI |
| CLCN3 | H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0100744 | 0.0148492820647 | 0.666666666667 | CYP26B1 CLCN3 | Abnormality of the humeroradial joint |
| REAC:R-HSA-5579015 | 0.0498224659464 | 0.333333333333 | CYP26B1 | Defective CYP26B1 causes RHFCA |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CLCN3 | ICOSLG | 0.978 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CLCN3 | CYP26B1 | 0.965 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes