hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07085.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYRM4 | LYR motif-containing protein 4 | 5 | UniProt NCBI |
| CDNF | Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor) | 4 | UniProt NCBI |
| NFS1 | Cysteine desulfurase (EC 2.8.1.7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5152 | 0.000103023242897 | 0.666666666667 | LYRM4 NFS1 | Iron sulfur cluster biogenesis |
| HP:0003648 | 0.00348901893966 | 0.666666666667 | LYRM4 NFS1 | Lacticaciduria |
| GO:0099128 | 0.00421361424067 | 0.666666666667 | LYRM4 NFS1 | mitochondrial iron-sulfur cluster assembly complex |
| GO:0044572 | 0.00842684400117 | 0.666666666667 | LYRM4 NFS1 | [4Fe-4S] cluster assembly |
| HP:0031956 | 0.0278951902268 | 0.666666666667 | LYRM4 NFS1 | Elevated circulating aspartate aminotransferase concentration |
| HP:0031964 | 0.0278951902268 | 0.666666666667 | LYRM4 NFS1 | Elevated circulating alanine aminotransferase concentration |
| KEGG:04122 | 0.0446022284792 | 0.333333333333 | NFS1 | Sulfur relay system |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LYRM4 | NFS1 | 1.0 | 0.932 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction boldt_WMM |
| CDNF | NFS1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LYRM4 | CDNF | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| LYRM4 | huMAP3_00863.1 huMAP3_00888.1 huMAP3_07085.1 |
| CDNF | huMAP3_00863.1 huMAP3_00888.1 huMAP3_07085.1 |
| NFS1 | huMAP3_00863.1 huMAP3_00888.1 huMAP3_07085.1 |