hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07152.1
Complex Portal: CPX-14931
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HSPB7 | Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) | 5 | UniProt NCBI |
| LAD1 | Ladinin-1 (Lad-1) (Linear IgA disease antigen) (LADA) | 4 | UniProt NCBI |
| FLNA | Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) | 5 | UniProt NCBI |
| ACTG1 | Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed] | 5 | UniProt NCBI |
| CAPN6 | Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM) | 5 | UniProt NCBI |
| CALM2 | Calmodulin-2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04971 | 0.00622027886669 | 0.4 | ACTG1 CALM2 | Gastric acid secretion |
| KEGG:05418 | 0.0303640260346 | 0.4 | ACTG1 CALM2 | Fluid shear stress and atherosclerosis |
| KEGG:04921 | 0.03088329966 | 0.4 | ACTG1 CALM2 | Oxytocin signaling pathway |
| WP:WP289 | 0.0492060648012 | 0.4 | ACTG1 CALM2 | Myometrial relaxation and contraction pathways |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HSPB7 | FLNA | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CAPN6 | FLNA | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LAD1 | FLNA | 0.959 | 0.262 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FLNA | ACTG1 | 0.958 | 0.6056 | hein_WMM hein () fraction boldt_WMM | |
| CALM2 | FLNA | 0.954 | 0.288 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt hein () boldt_WMM | |
| CALM2 | ACTG1 | 0.433 | 0.734 | hein_WMM gupta_WMM WMM_only boldt_WMM | |
| CAPN6 | CALM2 | 0.005 | bioplex3_HEK293 bioplex () | ||
| HSPB7 | CALM2 | 0.002 | bioplex3_HEK293 bioplex () bioplex3_HCT116 | ||
| LAD1 | CALM2 | 0.002 | 0.048 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes