hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07161.1
Complex Portal: CPX-17671
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IKZF3 | Zinc finger protein Aiolos (Ikaros family zinc finger protein 3) | 5 | UniProt NCBI |
| ELF2 | ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor) | 5 | UniProt NCBI |
| ZNF518B | Zinc finger protein 518B | 3 | UniProt NCBI |
| IKZF4 | Zinc finger protein Eos (Ikaros family zinc finger protein 4) | 5 | UniProt NCBI |
| IKZF2 | Zinc finger protein Helios (Ikaros family zinc finger protein 2) | 5 | UniProt NCBI |
| IKZF5 | Zinc finger protein Pegasus (Ikaros family zinc finger protein 5) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003700 | 0.00326965529559 | 1.0 | ELF2 ZNF518B IKZF3 IKZF5 IKZF2 IKZF4 | DNA-binding transcription factor activity |
| GO:1990837 | 0.00590399976487 | 1.0 | ELF2 ZNF518B IKZF3 IKZF5 IKZF2 IKZF4 | sequence-specific double-stranded DNA binding |
| GO:0043565 | 0.00907384039353 | 1.0 | ELF2 ZNF518B IKZF3 IKZF5 IKZF2 IKZF4 | sequence-specific DNA binding |
| GO:0003690 | 0.00922340628856 | 1.0 | ELF2 ZNF518B IKZF3 IKZF5 IKZF2 IKZF4 | double-stranded DNA binding |
| GO:0140110 | 0.0296672346661 | 1.0 | ELF2 ZNF518B IKZF3 IKZF5 IKZF2 IKZF4 | transcription regulator activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IKZF3 | IKZF4 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IKZF5 | IKZF2 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| IKZF5 | IKZF3 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| IKZF5 | IKZF4 | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF518B | IKZF5 | 0.966 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ELF2 | IKZF5 | 0.951 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| IKZF2 | IKZF4 | 0.797 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF518B | IKZF2 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | ||
| IKZF2 | IKZF3 | 0.36 | 0.182 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF518B | IKZF4 | 0.303 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF518B | IKZF3 | 0.303 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELF2 | IKZF3 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELF2 | IKZF4 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELF2 | IKZF2 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELF2 | ZNF518B | 0.085 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes