hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07166.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADCY6 | Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase) | 5 | UniProt NCBI |
| ZNF100 | Zinc finger protein 100 | 3 | UniProt NCBI |
| NEUROG2 | Neurogenin-2 (NGN-2) (Class A basic helix-loop-helix protein 8) (bHLHa8) (Protein atonal homolog 4) | 4 | UniProt NCBI |
| NEUROG3 | Neurogenin-3 (NGN-3) (Class A basic helix-loop-helix protein 7) (bHLHa7) (Protein atonal homolog 5) | 5 | UniProt NCBI |
| CSRP2 | Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (LIM domain only protein 5) (LMO-5) (Smooth muscle cell LIM protein) (SmLIM) | 5 | UniProt NCBI |
| SPHK2 | Sphingosine kinase 2 (SK 2) (SPK 2) (EC 2.7.1.91) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04371 | 0.0435090165647 | 0.333333333333 | ADCY6 SPHK2 | Apelin signaling pathway |
| KEGG:04072 | 0.0474921555213 | 0.333333333333 | ADCY6 SPHK2 | Phospholipase D signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NEUROG3 | SPHK2 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NEUROG2 | NEUROG3 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NEUROG3 | CSRP2 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZNF100 | NEUROG3 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ADCY6 | NEUROG3 | 0.953 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CSRP2 | SPHK2 | 0.594 | 0.024 | bioplex3_WMM WMM_only |
| ZNF100 | NEUROG2 | 0.303 | bioplex_WMM bioplex3_WMM WMM_only | |
| NEUROG2 | SPHK2 | 0.214 | bioplex3_WMM WMM_only | |
| ADCY6 | ZNF100 | 0.153 | bioplex_WMM bioplex3_WMM WMM_only | |
| ADCY6 | NEUROG2 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | |
| NEUROG2 | CSRP2 | 0.046 | bioplex3_WMM WMM_only | |
| ADCY6 | SPHK2 | 0.046 | 0.096 | bioplex3_WMM WMM_only |
| ZNF100 | SPHK2 | 0.042 | bioplex3_WMM WMM_only | |
| ZNF100 | CSRP2 | 0.009 | bioplex3_WMM WMM_only | |
| ADCY6 | CSRP2 | 0.008 | 0.094 | bioplex3_WMM WMM_only |
Related Complexes