hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07170.1

Complex Portal: CPX-18541

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
TRIP13	Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)	5	UniProt NCBI
ATP2A2	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)	5	UniProt NCBI
SLC25A1	Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)	5	UniProt NCBI
HSD17B12	Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1)	5	UniProt NCBI
UMPS	Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)]	5	UniProt NCBI
XPO1	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)	5	UniProt NCBI
MSH6	DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)	5	UniProt NCBI
CIAO2B	Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B)	5	UniProt NCBI
CSE1L	Exportin-2 (Exp2) (Cellular apoptosis susceptibility protein) (Chromosome segregation 1-like protein) (Importin-alpha re-exporter)	5	UniProt NCBI
SEC61A1	Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)	5	UniProt NCBI
ARL1	ADP-ribosylation factor-like protein 1	5	UniProt NCBI
TTC27	Tetratricopeptide repeat protein 27 (TPR repeat protein 27)	2	UniProt NCBI
XPOT	Exportin-T (Exportin(tRNA)) (tRNA exportin)	5	UniProt NCBI
FANCI	Fanconi anemia group I protein (Protein FACI)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:03013	0.00350089201053	0.25	CSE1L XPO1 XPOT	Nucleocytoplasmic transport
HP:0007565	0.0125726486101	0.25	TRIP13 FANCI MSH6	Multiple cafe-au-lait spots

Edges

Protein 1	Protein 2	Score	ProteomeHD
SEC61A1	XPO1	0.993	0.362
TRIP13	XPOT	0.992	0.09
UMPS	HSD17B12	0.992	0.05
SLC25A1	TRIP13	0.991	0.086
SLC25A1	HSD17B12	0.991	0.278
HSD17B12	XPOT	0.991	0.054
TRIP13	XPO1	0.99	0.24
TRIP13	ARL1	0.99	0.086
HSD17B12	CSE1L	0.99	0.13
XPOT	CSE1L	0.989	0.29
ATP2A2	XPO1	0.988	0.348
ATP2A2	XPOT	0.988	0.154
HSD17B12	XPO1	0.988	0.214
ARL1	XPOT	0.988	0.056
XPOT	XPO1	0.987	0.346
HSD17B12	FANCI	0.987	0.024
ATP2A2	CSE1L	0.985	0.162
SLC25A1	XPO1	0.985	0.360414457831
ARL1	XPO1	0.984	0.142
ATP2A2	HSD17B12	0.983	0.432
XPO1	CSE1L	0.982	0.608
UMPS	XPOT	0.981	0.192
MSH6	XPOT	0.981	0.13
SEC61A1	ARL1	0.981	0.186
SLC25A1	XPOT	0.979	0.116
SEC61A1	XPOT	0.979	0.06
ARL1	TTC27	0.978	0.034
TRIP13	SEC61A1	0.978	0.096
UMPS	XPO1	0.978	0.598
TRIP13	FANCI	0.978	0.116
XPOT	FANCI	0.978	0.116
UMPS	TRIP13	0.977	0.098
UMPS	FANCI	0.976	0.15
SEC61A1	HSD17B12	0.974	0.252
UMPS	ARL1	0.973	0.21
CIAO2B	TTC27	0.972	0.078
ATP2A2	SEC61A1	0.972	0.564
TRIP13	CSE1L	0.969	0.138
ATP2A2	FANCI	0.969	0.084
SLC25A1	ARL1	0.969	0.058
XPOT	CIAO2B	0.968	0.108
TRIP13	HSD17B12	0.965	0.012
XPO1	CIAO2B	0.964	0.2
SEC61A1	FANCI	0.964	0.064
TRIP13	TTC27	0.963	0.064
HSD17B12	TTC27	0.96	0.084
MSH6	FANCI	0.96	0.142
SLC25A1	FANCI	0.959	0.046
SEC61A1	CSE1L	0.958	0.162823529412
TTC27	FANCI	0.958	0.128
UMPS	CSE1L	0.956	0.344
XPOT	TTC27	0.956	0.224
CSE1L	FANCI	0.955	0.19
MSH6	TTC27	0.954	0.072
SLC25A1	TTC27	0.954	0.042
ARL1	HSD17B12	0.953	0.162
MSH6	ATP2A2	0.953	0.07
MSH6	XPO1	0.951	0.368
MSH6	HSD17B12	0.949	0.034
XPO1	FANCI	0.944	0.196756554307
MSH6	CIAO2B	0.939	0.054
CSE1L	TTC27	0.939	0.226333333333
MSH6	TRIP13	0.938	0.054
ATP2A2	TTC27	0.933	0.066
ATP2A2	TRIP13	0.927	0.066
TRIP13	CIAO2B	0.921	0.052
ARL1	FANCI	0.918	0.052
UMPS	TTC27	0.905	0.1
MSH6	SLC25A1	0.905	0.052
SEC61A1	TTC27	0.887	0.038
XPO1	TTC27	0.845	0.344
SLC25A1	UMPS	0.835	0.086
CIAO2B	FANCI	0.828	0.04
CSE1L	CIAO2B	0.818	0.158
ATP2A2	ARL1	0.772	0.28
MSH6	UMPS	0.752	0.13
MSH6	ARL1	0.666	0.044
MSH6	CSE1L	0.652	0.462
SEC61A1	CIAO2B	0.638	0.056
SLC25A1	CSE1L	0.565	0.236
HSD17B12	CIAO2B	0.536	0.062
ATP2A2	CIAO2B	0.518	0.05
UMPS	CIAO2B	0.43	0.092
MSH6	SEC61A1	0.422	0.028
SLC25A1	SEC61A1	0.411	0.256
UMPS	SEC61A1	0.407	0.094
SLC25A1	ATP2A2	0.213	0.418
ARL1	CSE1L	0.172	0.212
ARL1	CIAO2B	0.166	0.036
UMPS	ATP2A2	0.119	0.15
SLC25A1	CIAO2B	0.095	0.036

Related Complexes

Genename	Complexes
TRIP13	huMAP3_03513.1 huMAP3_06791.1 huMAP3_07170.1 huMAP3_08764.1 huMAP3_09042.1
ATP2A2	huMAP3_02810.1 huMAP3_03704.1 huMAP3_06247.1 huMAP3_07170.1 huMAP3_07262.1 huMAP3_09592.1 huMAP3_10473.1
SLC25A1	huMAP3_01090.1 huMAP3_07170.1 huMAP3_08764.1 huMAP3_09042.1 huMAP3_11101.1
HSD17B12	huMAP3_06189.1 huMAP3_07170.1 huMAP3_07410.1 huMAP3_07672.1 huMAP3_09824.1
UMPS	huMAP3_01554.1 huMAP3_07170.1 huMAP3_07670.1 huMAP3_07789.1 huMAP3_09042.1 huMAP3_10240.1 huMAP3_12841.1
XPO1	huMAP3_06791.1 huMAP3_07170.1 huMAP3_08764.1 huMAP3_09042.1 huMAP3_09592.1
MSH6	huMAP3_00930.1 huMAP3_05669.1 huMAP3_05825.1 huMAP3_06319.1 huMAP3_07170.1 huMAP3_07283.1 huMAP3_08764.1 huMAP3_09042.1 huMAP3_09664.1 huMAP3_10240.1 huMAP3_10665.1
CIAO2B	huMAP3_07011.1 huMAP3_07170.1 huMAP3_07379.1 huMAP3_08439.1 huMAP3_09042.1 huMAP3_09592.1
CSE1L	huMAP3_06791.1 huMAP3_07170.1 huMAP3_09042.1 huMAP3_09592.1
SEC61A1	huMAP3_05784.1 huMAP3_06247.1 huMAP3_07170.1 huMAP3_08448.1 huMAP3_09592.1
ARL1	huMAP3_06140.1 huMAP3_07170.1 huMAP3_08764.1 huMAP3_09042.1 huMAP3_09550.1 huMAP3_10240.1 huMAP3_14055.1
TTC27	huMAP3_07170.1 huMAP3_08764.1 huMAP3_09042.1
XPOT	huMAP3_06791.1 huMAP3_07170.1 huMAP3_08764.1 huMAP3_09042.1 huMAP3_09228.1
FANCI	huMAP3_07170.1 huMAP3_07789.1 huMAP3_09042.1 huMAP3_09592.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07170.1

Complex Portal: CPX-18541