hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07172.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MBIP | MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein) | 5 | UniProt NCBI |
| KAT14 | Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14) | 5 | UniProt NCBI |
| YEATS2 | YEATS domain-containing protein 2 | 5 | UniProt NCBI |
| ZZZ3 | ZZ-type zinc finger-containing protein 3 | 5 | UniProt NCBI |
| TADA2A | Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6657 | 6.61547084549e-15 | 1.0 | KAT14 ZZZ3 TADA2A MBIP YEATS2 | ATAC complex, GCN5-linked |
| CORUM:6665 | 5.25562406058e-14 | 1.0 | KAT14 ZZZ3 TADA2A MBIP YEATS2 | ATAC complex, YEATS2-linked |
| REAC:R-HSA-9772755 | 3.89605743335e-08 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | Formation of WDR5-containing histone-modifying complexes |
| GO:0140672 | 9.40213012535e-08 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | ATAC complex |
| GO:0090043 | 3.12897432326e-07 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | regulation of tubulin deacetylation |
| GO:0090042 | 6.36865069892e-07 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | tubulin deacetylation |
| GO:0090311 | 9.61435992643e-07 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | regulation of protein deacetylation |
| REAC:R-HSA-3214847 | 4.67050314665e-06 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | HATs acetylate histones |
| GO:0006476 | 6.87695434453e-06 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | protein deacetylation |
| GO:0070461 | 7.73614931468e-06 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | SAGA-type complex |
| REAC:R-HSA-212165 | 1.45553942328e-05 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | Epigenetic regulation of gene expression |
| GO:0035601 | 1.46952249556e-05 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | protein deacylation |
| GO:0098732 | 1.46952249556e-05 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | macromolecule deacylation |
| GO:0045995 | 5.56532631373e-05 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | regulation of embryonic development |
| REAC:R-HSA-4839726 | 6.69531345818e-05 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | Chromatin organization |
| REAC:R-HSA-3247509 | 6.69531345818e-05 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | Chromatin modifying enzymes |
| GO:0000123 | 0.000305379790485 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | histone acetyltransferase complex |
| GO:1902493 | 0.000472796969853 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | acetyltransferase complex |
| GO:0031248 | 0.000472796969853 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | protein acetyltransferase complex |
| GO:0051302 | 0.000727710984203 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | regulation of cell division |
| GO:0072686 | 0.00334425988582 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | mitotic spindle |
| GO:0051301 | 0.0163652485476 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | cell division |
| GO:0005819 | 0.0439687701346 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | spindle |
| REAC:R-HSA-74160 | 0.046583533294 | 0.8 | KAT14 ZZZ3 MBIP YEATS2 | Gene expression (Transcription) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MBIP | ZZZ3 | 1.0 | 0.288 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MBIP | YEATS2 | 1.0 | 0.186 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MBIP | KAT14 | 0.999 | 0.282 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| YEATS2 | ZZZ3 | 0.999 | 0.318 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| MBIP | TADA2A | 0.998 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ZZZ3 | TADA2A | 0.998 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| YEATS2 | TADA2A | 0.998 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| KAT14 | YEATS2 | 0.996 | 0.224 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| KAT14 | ZZZ3 | 0.991 | 0.304 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| KAT14 | TADA2A | 0.989 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes