hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07229.1
Complex Portal: CPX-24173
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRKCA | Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) | 5 | UniProt NCBI |
| GCLM | Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit) | 5 | UniProt NCBI |
| CCR3 | C-C chemokine receptor type 3 (C C CKR3) (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR 3) (CKR3) (Eosinophil eotaxin receptor) (CD antigen CD193) | 5 | UniProt NCBI |
| PRKCG | Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05163 | 0.0138758373086 | 0.666666666667 | PRKCG CCR3 | Human cytomegalovirus infection |
| CORUM:7186 | 0.0499402709677 | 0.333333333333 | GCLM | Glutamate-cysteine ligase |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PRKCA | GCLM | 0.997 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| PRKCA | PRKCG | 0.983 | 0.102 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PRKCA | CCR3 | 0.958 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PRKCG | GCLM | 0.497 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PRKCA | huMAP3_01710.1 huMAP3_06641.1 huMAP3_07229.1 huMAP3_12853.1 |
| GCLM | huMAP3_03468.1 huMAP3_07229.1 huMAP3_11353.1 huMAP3_12407.1 huMAP3_14769.1 |
| CCR3 | huMAP3_01710.1 huMAP3_03601.1 huMAP3_07229.1 |
| PRKCG | huMAP3_01710.1 huMAP3_06641.1 huMAP3_07229.1 huMAP3_12853.1 |