hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07248.1

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
SAP18	Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)	5	UniProt NCBI
LUC7L3	Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)	5	UniProt NCBI
SNRNP70	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)	5	UniProt NCBI
RSBN1L	Lysine-specific demethylase RSBN1L (EC 1.14.11.-) (Round spermatid basic protein 1-like protein)	3	UniProt NCBI
SNIP1	Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1)	5	UniProt NCBI
PRPF4B	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)	5	UniProt NCBI
NKTR	NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase)	5	UniProt NCBI
ACIN1	Apoptotic chromatin condensation inducer in the nucleus (Acinus)	5	UniProt NCBI
GPATCH8	G patch domain-containing protein 8	4	UniProt NCBI
RNPS1	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)	5	UniProt NCBI
NFKBIL1	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)	5	UniProt NCBI
U2AF2	Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-72163	6.84162555235e-09	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	8.7107121983e-09	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	mRNA Splicing
CORUM:760	2.10621603952e-08	0.272727272727	ACIN1 SAP18 RNPS1	Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L
REAC:R-HSA-72203	6.04870606313e-08	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	Processing of Capped Intron-Containing Pre-mRNA
CORUM:351	1.97235159507e-06	0.454545454545	LUC7L3 RNPS1 ACIN1 PRPF4B SNRNP70	Spliceosome
GO:0000377	9.48342166719e-06	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000398	9.48342166719e-06	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	mRNA splicing, via spliceosome
GO:0000375	1.05301297737e-05	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	RNA splicing, via transesterification reactions
REAC:R-HSA-8953854	3.46043041626e-05	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	Metabolism of RNA
GO:0006397	4.76399802706e-05	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	mRNA processing
GO:0061574	6.34131776058e-05	0.272727272727	ACIN1 SAP18 RNPS1	ASAP complex
GO:0008380	8.83222235795e-05	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	RNA splicing
HPA:0380512	0.000344593637234	0.909090909091	RNPS1 RSBN1L SNRNP70 PRPF4B NKTR SAP18 ACIN1 LUC7L3 GPATCH8 SNIP1	placenta; decidual cells[>=Medium]
GO:0016071	0.00156577216007	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	mRNA metabolic process
KEGG:03015	0.00189424703244	0.272727272727	ACIN1 SAP18 RNPS1	mRNA surveillance pathway
KEGG:03013	0.00258780243418	0.272727272727	ACIN1 SAP18 RNPS1	Nucleocytoplasmic transport
HPA:0380511	0.00589578471723	0.909090909091	RNPS1 RSBN1L SNRNP70 PRPF4B NKTR SAP18 ACIN1 LUC7L3 GPATCH8 SNIP1	placenta; decidual cells[>=Low]
HPA:0080123	0.00716960233359	0.454545454545	LUC7L3 RNPS1 ACIN1 SAP18 SNRNP70	caudate; glial cells[High]
GO:0048025	0.00883419058623	0.272727272727	ACIN1 SAP18 RNPS1	negative regulation of mRNA splicing, via spliceosome
WP:WP411	0.0093084590096	0.272727272727	SNRNP70 PRPF4B RNPS1	mRNA processing
GO:0050686	0.012862104388	0.272727272727	ACIN1 SAP18 RNPS1	negative regulation of mRNA processing
GO:0006396	0.0146321583166	0.636363636364	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 SAP18	RNA processing
GO:0035145	0.0179543561972	0.272727272727	ACIN1 SAP18 RNPS1	exon-exon junction complex
GO:0033119	0.0209381437171	0.272727272727	ACIN1 SAP18 RNPS1	negative regulation of RNA splicing
HPA:0080122	0.0316038671798	0.636363636364	ACIN1 RNPS1 SNIP1 SNRNP70 LUC7L3 GPATCH8 SAP18	caudate; glial cells[>=Medium]
GO:0003723	0.0440585189181	0.727272727273	ACIN1 PRPF4B RNPS1 SNIP1 SNRNP70 LUC7L3 GPATCH8 SAP18	RNA binding

Edges

Protein 1	Protein 2	Score	ProteomeHD
ACIN1	SAP18	1.0
RNPS1	GPATCH8	0.999	0.376
ACIN1	NFKBIL1	0.999	0.082
RNPS1	SAP18	0.999
ACIN1	RNPS1	0.998	0.92
RNPS1	SNIP1	0.996	0.742
LUC7L3	RSBN1L	0.996	0.082
ACIN1	NKTR	0.996	0.362
RNPS1	LUC7L3	0.995	0.894
RNPS1	NKTR	0.994	0.316
RNPS1	NFKBIL1	0.993	0.108
RNPS1	U2AF2	0.993	0.882
ACIN1	SNIP1	0.992	0.642
LUC7L3	NFKBIL1	0.991	0.08
U2AF2	LUC7L3	0.991	0.602
RNPS1	PRPF4B	0.99	0.824
NFKBIL1	SAP18	0.99
LUC7L3	SNIP1	0.988	0.734
RNPS1	RSBN1L	0.988	0.092
SAP18	PRPF4B	0.986
NKTR	SAP18	0.985
LUC7L3	PRPF4B	0.982	0.634
ACIN1	U2AF2	0.98	0.73
SNRNP70	SNIP1	0.98	0.734
SNRNP70	RNPS1	0.97	0.992
GPATCH8	SAP18	0.963
ACIN1	LUC7L3	0.958	0.498571428571
NFKBIL1	PRPF4B	0.955	0.058
NFKBIL1	RSBN1L	0.954	0.1
U2AF2	PRPF4B	0.953	0.646
LUC7L3	SAP18	0.949
RSBN1L	PRPF4B	0.947	0.172
U2AF2	NFKBIL1	0.931	0.112
NKTR	GPATCH8	0.928	0.178
U2AF2	SNIP1	0.923	0.672
LUC7L3	NKTR	0.919	0.3
NKTR	SNIP1	0.889	0.217
ACIN1	GPATCH8	0.886	0.35
SNRNP70	LUC7L3	0.879	0.798
NFKBIL1	GPATCH8	0.878	0.062
NKTR	PRPF4B	0.828	0.242
U2AF2	SAP18	0.819
LUC7L3	GPATCH8	0.817	0.264
ACIN1	PRPF4B	0.775	0.666
U2AF2	GPATCH8	0.741	0.25
NKTR	RSBN1L	0.594	0.106
U2AF2	RSBN1L	0.529	0.202
U2AF2	NKTR	0.459	0.31
SNRNP70	GPATCH8	0.44	0.286636363636
GPATCH8	PRPF4B	0.434	0.256
SNIP1	PRPF4B	0.432	0.58
SNRNP70	NKTR	0.393	0.224
RSBN1L	GPATCH8	0.33	0.056
NKTR	NFKBIL1	0.308	0.128
SNRNP70	ACIN1	0.279	0.784
GPATCH8	SNIP1	0.277	0.326
SNRNP70	U2AF2	0.228	0.878
ACIN1	RSBN1L	0.201	0.226
SNIP1	SAP18	0.194
SNRNP70	NFKBIL1	0.143	0.09
SNRNP70	PRPF4B	0.128	0.766
SNRNP70	RSBN1L	0.078	0.128
RSBN1L	SAP18	0.076
SNRNP70	SAP18	0.036
RSBN1L	SNIP1	0.016	0.14

Related Complexes

Genename	Complexes
SAP18	huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
LUC7L3	huMAP3_00442.1 huMAP3_03936.1 huMAP3_05807.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_08141.1 huMAP3_09621.1 huMAP3_11073.1
SNRNP70	huMAP3_00197.1 huMAP3_06391.1 huMAP3_07248.1 huMAP3_07267.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_11073.1
RSBN1L	huMAP3_02403.1 huMAP3_02739.1 huMAP3_03128.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08715.1 huMAP3_08769.1 huMAP3_09607.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_11073.1
SNIP1	huMAP3_03772.1 huMAP3_06391.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10139.1 huMAP3_10564.1 huMAP3_11073.1
PRPF4B	huMAP3_05807.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_11073.1
NKTR	huMAP3_00489.1 huMAP3_01312.1 huMAP3_02739.1 huMAP3_04339.1 huMAP3_05069.1 huMAP3_05740.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07309.1 huMAP3_07835.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1 huMAP3_11261.1
ACIN1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
GPATCH8	huMAP3_02739.1 huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_07248.1 huMAP3_07737.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09095.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10789.1 huMAP3_11073.1
RNPS1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_07267.1 huMAP3_07291.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
NFKBIL1	huMAP3_00526.1 huMAP3_03529.1 huMAP3_06487.1 huMAP3_07248.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10611.1 huMAP3_11073.1
U2AF2	huMAP3_00398.1 huMAP3_00442.1 huMAP3_00489.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_07835.1 huMAP3_08360.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_11073.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07248.1