hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07248.1

Complex Portal: CPX-15898

Confidence: Very High

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Genename	Protein Name	Uniprot Annotation Score	Links
ACIN1	Apoptotic chromatin condensation inducer in the nucleus (Acinus)	5	UniProt NCBI
GPATCH8	G patch domain-containing protein 8	4	UniProt NCBI
LUC7L3	Luc7-like protein 3 (Cisplatin resistance-associated-overexpressed protein) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18) (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1)	5	UniProt NCBI
NFKBIL1	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)	5	UniProt NCBI
NKTR	NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase)	5	UniProt NCBI
PRPF4B	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)	5	UniProt NCBI
RNPS1	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)	5	UniProt NCBI
RSBN1L	Lysine-specific demethylase RSBN1L (EC 1.14.11.-) (Round spermatid basic protein 1-like protein)	3	UniProt NCBI
SAP18	Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)	5	UniProt NCBI
SNIP1	Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1)	5	UniProt NCBI

Showing 1 to 10 of 12 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-72163	6.84162555235e-09	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	8.7107121983e-09	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	mRNA Splicing
CORUM:760	2.10621603952e-08	0.272727272727	RNPS1 SAP18 ACIN1	Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L
REAC:R-HSA-72203	6.04870606313e-08	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	Processing of Capped Intron-Containing Pre-mRNA
CORUM:351	1.97235159507e-06	0.454545454545	SNRNP70 RNPS1 ACIN1 LUC7L3 PRPF4B	Spliceosome
GO:0000377	9.48342166719e-06	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000398	9.48342166719e-06	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	mRNA splicing, via spliceosome
GO:0000375	1.05301297737e-05	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	RNA splicing, via transesterification reactions
REAC:R-HSA-8953854	3.46043041626e-05	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	Metabolism of RNA
GO:0006397	4.76399802706e-05	0.636363636364	SNIP1 SAP18 RNPS1 PRPF4B SNRNP70 LUC7L3 ACIN1	mRNA processing

Showing 1 to 10 of 26 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ACIN1	SAP18	1.0
RNPS1	GPATCH8	0.999	0.376
ACIN1	NFKBIL1	0.999	0.082
RNPS1	SAP18	0.999		structurally_consistent (dimer)
ACIN1	RNPS1	0.998	0.92	mutually_exclusive (P61326)
RNPS1	SNIP1	0.996	0.742	mutually_exclusive (P49760)
LUC7L3	RSBN1L	0.996	0.082
ACIN1	NKTR	0.996	0.362
RNPS1	LUC7L3	0.995	0.894
RNPS1	NKTR	0.994	0.316

Showing 1 to 10 of 65 entries

Related Complexes

Genename	Complexes
SAP18	huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
LUC7L3	huMAP3_00442.1 huMAP3_03936.1 huMAP3_05807.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_08141.1 huMAP3_09621.1 huMAP3_11073.1
SNRNP70	huMAP3_00197.1 huMAP3_06391.1 huMAP3_07248.1 huMAP3_07267.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_11073.1
RSBN1L	huMAP3_02403.1 huMAP3_02739.1 huMAP3_03128.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08715.1 huMAP3_08769.1 huMAP3_09607.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_11073.1
SNIP1	huMAP3_03772.1 huMAP3_06391.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10139.1 huMAP3_10564.1 huMAP3_11073.1
PRPF4B	huMAP3_05807.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_11073.1
NKTR	huMAP3_00489.1 huMAP3_01312.1 huMAP3_02739.1 huMAP3_04339.1 huMAP3_05069.1 huMAP3_05740.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07309.1 huMAP3_07835.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1 huMAP3_11261.1
ACIN1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
GPATCH8	huMAP3_02739.1 huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_07248.1 huMAP3_07737.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09095.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10789.1 huMAP3_11073.1
RNPS1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_07267.1 huMAP3_07291.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
NFKBIL1	huMAP3_00526.1 huMAP3_03529.1 huMAP3_06487.1 huMAP3_07248.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10611.1 huMAP3_11073.1
U2AF2	huMAP3_00398.1 huMAP3_00442.1 huMAP3_00489.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_07835.1 huMAP3_08360.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_11073.1