hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07294.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAD2L1BP | MAD2L1-binding protein (Caught by MAD2 protein) (p31(comet)) | 5 | UniProt NCBI |
| MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181) | 5 | UniProt NCBI |
| PYROXD1 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) | 5 | UniProt NCBI |
| TPR | Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) | 5 | UniProt NCBI |
| ZSCAN29 | Zinc finger and SCAN domain-containing protein 29 (Zinc finger protein 690) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0090233 | 0.00842684400117 | 0.5 | MAD2L1BP MAD1L1 | negative regulation of spindle checkpoint |
| GO:0140499 | 0.00842684400117 | 0.5 | MAD2L1BP MAD1L1 | negative regulation of mitotic spindle assembly checkpoint signaling |
| GO:1902426 | 0.00842684400117 | 0.5 | MAD2L1BP MAD1L1 | deactivation of mitotic spindle assembly checkpoint |
| CORUM:1813 | 0.0249718442456 | 0.25 | MAD1L1 | MAD1L1 homodimer complex |
| KEGG:04110 | 0.0280208578488 | 0.5 | MAD2L1BP MAD1L1 | Cell cycle |
| CORUM:1814 | 0.049938562206 | 0.25 | MAD1L1 | MAD1L1-MAD2L1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MAD1L1 | MAD2L1BP | 1.0 | 0.372 | hein_WMM bioplex3_HEK293 bioplex3_WMM hein () bioplex3_HCT116 |
| MAD2L1BP | PYROXD1 | 0.997 | 0.146 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ZSCAN29 | MAD2L1BP | 0.967 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TPR | MAD2L1BP | 0.956 | 0.202 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| MAD1L1 | TPR | 0.901 | 0.398 | hein_WMM bioplex_WMM Guru bioplex3_WMM fraction |
| MAD1L1 | PYROXD1 | 0.892 | 0.126 | bioplex3_WMM WMM_only |
| TPR | PYROXD1 | 0.293 | 0.15 | bioplex3_WMM WMM_only |
| MAD1L1 | ZSCAN29 | 0.102 | bioplex3_WMM WMM_only | |
| ZSCAN29 | TPR | 0.023 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 |
Related Complexes