hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07299.1

Complex Portal: CPX-12845

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
ZNF512B	Zinc finger protein 512B	5	UniProt NCBI
RBBP4	Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)	5	UniProt NCBI
SMARCA1	Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)	5	UniProt NCBI
CCDC71	Coiled-coil domain-containing protein 71	2	UniProt NCBI
BPTF	Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)	5	UniProt NCBI
RBBP7	Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)	5	UniProt NCBI
PWWP2B	PWWP domain-containing protein 2B	5	UniProt NCBI
HAT1	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1)	5	UniProt NCBI
NPAT	Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220)	5	UniProt NCBI
SHPRH	E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)	5	UniProt NCBI
SALL1	Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)	5	UniProt NCBI
ZNF521	Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:919	2.10621603952e-08	0.272727272727	RBBP4 RBBP7 BPTF	hNURF complex
CORUM:100	2.10621603952e-08	0.272727272727	RBBP4 RBBP7 BPTF	hNURF complex
CORUM:3048	0.000341558207359	0.181818181818	RBBP4 RBBP7	mSin3A complex
CORUM:889	0.000341558207359	0.181818181818	RBBP4 RBBP7	MTA1-HDAC core complex
CORUM:105	0.000341558207359	0.181818181818	RBBP4 RBBP7	Polycomb repressive complex 2 (PRC 2)
CORUM:886	0.000512126948792	0.181818181818	RBBP4 RBBP7	MTA1 complex
GO:0016589	0.000554182028596	0.272727272727	RBBP4 RBBP7 BPTF	NURF complex
CORUM:1150	0.000716683342105	0.181818181818	RBBP4 HAT1	Histone H3.3 complex
CORUM:732	0.000716683342105	0.181818181818	RBBP4 RBBP7	SIN3 complex
CORUM:698	0.000716683342105	0.181818181818	RBBP4 RBBP7	SIN3-HDAC-SAP30-ARID4 complex
CORUM:695	0.000716683342105	0.181818181818	RBBP4 RBBP7	SIN3-HDAC-SAP30-ARID4 complex
CORUM:596	0.000716683342105	0.181818181818	RBBP4 RBBP7	SIN3-HDAC-SAP30-ARID4 complex
CORUM:283	0.000716683342105	0.181818181818	RBBP4 RBBP7	Sin3 complex
CORUM:650	0.000716683342105	0.181818181818	RBBP4 RBBP7	HDAC2-asscociated core complex
CORUM:61	0.000716683342105	0.181818181818	RBBP4 RBBP7	Mi2/NuRD complex
CORUM:54	0.000716683342105	0.181818181818	RBBP4 RBBP7	SIN3 complex
CORUM:1149	0.000955185435728	0.181818181818	RBBP4 HAT1	Histone H3.1 complex
CORUM:587	0.000955185435728	0.181818181818	RBBP4 RBBP7	NuRD.1 complex
CORUM:591	0.000955185435728	0.181818181818	RBBP4 RBBP7	SAP complex (Sin3-associated protein complex)
CORUM:888	0.000955185435728	0.181818181818	RBBP4 RBBP7	MTA2 complex
CORUM:62	0.000955185435728	0.181818181818	RBBP4 RBBP7	MeCP1 complex
CORUM:696	0.000955185435728	0.181818181818	RBBP4 RBBP7	BRMS1-SIN3-HDAC complex
CORUM:592	0.00122759131257	0.181818181818	RBBP4 RBBP7	SAP complex (Sin3-associated protein complex)
CORUM:738	0.00122759131257	0.181818181818	RBBP4 RBBP7	SIN3-ING1b complex I
CORUM:646	0.00122759131257	0.181818181818	RBBP4 RBBP7	HDAC1-associated protein complex
CORUM:649	0.00122759131257	0.181818181818	RBBP4 RBBP7	HDAC1-associated core complex cII
CORUM:659	0.00122759131257	0.181818181818	RBBP4 RBBP7	MeCP1 complex
CORUM:685	0.00122759131257	0.181818181818	RBBP4 RBBP7	MeCP1 complex
CORUM:743	0.00153385909002	0.181818181818	RBBP4 RBBP7	SIN3-SAP25 complex
CORUM:691	0.00153385909002	0.181818181818	RBBP4 RBBP7	SIN3-SAP25 complex
CORUM:2851	0.00187394691988	0.181818181818	RBBP4 RBBP7	ING2 complex
KEGG:03082	0.00282428645352	0.272727272727	RBBP4 RBBP7 BPTF	ATP-dependent chromatin remodeling
WP:WP2446	0.00327481493699	0.272727272727	RBBP4 NPAT RBBP7	Retinoblastoma gene in cancer
CORUM:282	0.00408022457695	0.181818181818	RBBP4 RBBP7	SNF2h-cohesin-NuRD complex
CORUM:2721	0.00408022457695	0.181818181818	RBBP4 RBBP7	HCF-1 complex
CORUM:739	0.00408022457695	0.181818181818	RBBP4 RBBP7	SIN3-ING1b complex II
CORUM:632	0.00462235583528	0.181818181818	RBBP4 RBBP7	Anti-HDAC2 complex
HPA:0471383	0.00568047694226	0.181818181818	RBBP4 RBBP7	skin 2; arrector pili muscle cells[High]
GO:0031010	0.00574694403184	0.272727272727	RBBP4 RBBP7 BPTF	ISWI-type complex
HPA:0620223	0.00605297878778	0.545454545455	RBBP4 SHPRH RBBP7 SALL1 HAT1 ZNF521	vagina; squamous epithelial cells[High]
WP:WP2916	0.00641421525353	0.181818181818	RBBP4 RBBP7	Interactome of polycomb repressive complex 2 PRC2
CORUM:1257	0.0127895235697	0.181818181818	RBBP4 RBBP7	ALL-1 supercomplex
HPA:0471433	0.0183496241297	0.181818181818	RBBP4 RBBP7	skin 2; extracellular matrix[High]
WP:WP4320	0.0352932028921	0.181818181818	RBBP4 RBBP7	Effect of progerin on genes involved in Hutchinson Gilford progeria syndrome
HPA:0471382	0.0381379224589	0.181818181818	RBBP4 RBBP7	skin 2; arrector pili muscle cells[>=Medium]
HPA:0461393	0.0427150544502	0.272727272727	RBBP4 HAT1 RBBP7	skin 1; cells in basal layer[High]
HPA:0570773	0.0491495156852	0.272727272727	RBBP4 HAT1 RBBP7	testis; peritubular cells[High]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RBBP4	RBBP7	1.0	0.664	structurally_consistent (dimer)
BPTF	RBBP7	0.999	0.094
RBBP7	HAT1	0.999	0.496	structurally_consistent (dimer)
RBBP4	NPAT	0.998	0.14
RBBP7	NPAT	0.997	0.186
RBBP4	PWWP2B	0.996		structurally_consistent (dimer)
RBBP4	BPTF	0.995	0.214
SHPRH	RBBP7	0.993	0.218	structurally_consistent (dimer)
CCDC71	RBBP7	0.992	0.11
PWWP2B	RBBP7	0.99
RBBP7	ZNF521	0.989	0.098
RBBP4	HAT1	0.987	0.348	mixed_interface
ZNF512B	RBBP7	0.984	0.132
RBBP4	ZNF512B	0.979	0.294
RBBP4	ZNF521	0.976	0.190285714286
ZNF512B	HAT1	0.975	0.098
RBBP4	SMARCA1	0.972	0.216
HAT1	NPAT	0.969	0.158
RBBP4	SHPRH	0.969	0.119	structurally_consistent (dimer)
SMARCA1	RBBP7	0.965	0.086
RBBP7	SALL1	0.963	0.0821428571429	structurally_consistent (dimer)
RBBP4	CCDC71	0.95	0.206
SMARCA1	BPTF	0.933	0.214
SMARCA1	NPAT	0.902	0.118
BPTF	HAT1	0.88	0.054
BPTF	NPAT	0.784	0.16
ZNF512B	SHPRH	0.697	0.146
CCDC71	ZNF521	0.614	0.05
ZNF512B	ZNF521	0.605	0.098
SMARCA1	PWWP2B	0.595
PWWP2B	HAT1	0.589
BPTF	PWWP2B	0.555
ZNF512B	CCDC71	0.551	0.066
SHPRH	NPAT	0.537	0.09
SHPRH	HAT1	0.536	0.076
PWWP2B	NPAT	0.501
RBBP4	SALL1	0.476	0.072
NPAT	ZNF521	0.447	0.072
BPTF	ZNF512B	0.405	0.292
ZNF512B	NPAT	0.403	0.086
ZNF512B	SALL1	0.361	0.078
SMARCA1	ZNF512B	0.361	0.172
PWWP2B	CCDC71	0.359
BPTF	CCDC71	0.357	0.098
SHPRH	CCDC71	0.357	0.058
BPTF	SALL1	0.334	0.092
PWWP2B	ZNF521	0.332
SHPRH	ZNF521	0.324	0.076
SMARCA1	SHPRH	0.324	0.046
BPTF	ZNF521	0.324	0.124
CCDC71	NPAT	0.3	0.144
BPTF	SHPRH	0.283	0.066
CCDC71	HAT1	0.278	0.102
SMARCA1	SALL1	0.272	0.04
HAT1	SALL1	0.248	0.096
SHPRH	SALL1	0.247	0.08
PWWP2B	ZNF512B	0.241
SMARCA1	CCDC71	0.227	0.056
CCDC71	SALL1	0.219	0.102
NPAT	SALL1	0.16	0.132
SMARCA1	ZNF521	0.146	0.076
SMARCA1	HAT1	0.139	0.038
HAT1	ZNF521	0.114	0.06
ZNF521	SALL1	0.114	0.048
PWWP2B	SHPRH	0.106		mutually_exclusive (Q09028)
PWWP2B	SALL1	0.035

Related Complexes

Genename	Complexes
ZNF512B	huMAP3_00206.1 huMAP3_06728.1 huMAP3_07299.1 huMAP3_08906.1 huMAP3_09499.1 huMAP3_10472.1 huMAP3_13875.1 huMAP3_15128.1
RBBP4	huMAP3_00206.1 huMAP3_06728.1 huMAP3_07299.1 huMAP3_08906.1 huMAP3_09499.1 huMAP3_10472.1 huMAP3_12711.1 huMAP3_13482.1 huMAP3_15128.1
SMARCA1	huMAP3_00206.1 huMAP3_00746.1 huMAP3_06728.1 huMAP3_07299.1 huMAP3_08549.1 huMAP3_08906.1 huMAP3_09198.1 huMAP3_09499.1 huMAP3_10118.1 huMAP3_10472.1 huMAP3_13482.1 huMAP3_13516.1 huMAP3_14567.1 huMAP3_15095.1 huMAP3_15128.1
CCDC71	huMAP3_00429.1 huMAP3_01287.1 huMAP3_06889.1 huMAP3_07299.1 huMAP3_08605.1 huMAP3_08800.1 huMAP3_09031.1 huMAP3_09232.1 huMAP3_10118.1 huMAP3_10311.1 huMAP3_13482.1 huMAP3_15128.1
BPTF	huMAP3_00206.1 huMAP3_00746.1 huMAP3_06728.1 huMAP3_07299.1 huMAP3_08833.1 huMAP3_08906.1 huMAP3_09198.1 huMAP3_09499.1 huMAP3_10472.1 huMAP3_10593.1 huMAP3_13482.1 huMAP3_14567.1 huMAP3_15095.1 huMAP3_15128.1
RBBP7	huMAP3_00429.1 huMAP3_04616.1 huMAP3_06728.1 huMAP3_07299.1 huMAP3_08800.1 huMAP3_08906.1 huMAP3_09031.1 huMAP3_09499.1 huMAP3_10118.1 huMAP3_10472.1 huMAP3_13482.1 huMAP3_15128.1
PWWP2B	huMAP3_00206.1 huMAP3_00429.1 huMAP3_03441.1 huMAP3_06728.1 huMAP3_06889.1 huMAP3_07158.1 huMAP3_07299.1 huMAP3_08290.1 huMAP3_08800.1 huMAP3_08906.1 huMAP3_09031.1 huMAP3_09499.1 huMAP3_10118.1 huMAP3_10472.1 huMAP3_13482.1 huMAP3_15128.1
HAT1	huMAP3_01440.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07299.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_13482.1 huMAP3_15128.1
NPAT	huMAP3_01440.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07299.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_15128.1
SHPRH	huMAP3_00429.1 huMAP3_04616.1 huMAP3_06728.1 huMAP3_07299.1 huMAP3_08906.1 huMAP3_09499.1 huMAP3_10118.1 huMAP3_10472.1 huMAP3_12711.1 huMAP3_13482.1 huMAP3_15128.1
SALL1	huMAP3_03283.1 huMAP3_07299.1 huMAP3_10116.1 huMAP3_11529.1 huMAP3_15128.1
ZNF521	huMAP3_02790.1 huMAP3_05579.1 huMAP3_07299.1 huMAP3_08730.1 huMAP3_08738.1 huMAP3_09499.1 huMAP3_10324.1 huMAP3_10472.1 huMAP3_13827.1 huMAP3_15128.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07299.1

Complex Portal: CPX-12845