hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07305.1

Complex Portal: CPX-15993

Confidence: Very High

Show entries

Search:

Genename	Protein Name	Uniprot Annotation Score	Links
C16orf96	Uncharacterized protein C16orf96	2	UniProt NCBI
ERRFI1	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (MIG-6)	5	UniProt NCBI
GAREM2	GRB2-associated and regulator of MAPK protein 2 (GRB2-associated and regulator of MAPK1-like)	3	UniProt NCBI
GLS2	Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)	5	UniProt NCBI
GRB2	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)	5	UniProt NCBI
SHC1	SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)	5	UniProt NCBI
SOS2	Son of sevenless homolog 2 (SOS-2)	5	UniProt NCBI

Showing 1 to 7 of 7 entries

Show entries

Search:

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP4928	0.000914914863609	0.333333333333	SOS2 GAREM2	MAPK pathway in congenital thyroid cancer
KEGG:05206	0.00103019356944	0.5	SOS2 GLS2 GRB2	MicroRNAs in cancer
WP:WP437	0.00131518658903	0.5	GRB2 SOS2 ERRFI1	EGF EGFR signaling pathway
REAC:R-HSA-8983432	0.00200991204249	0.333333333333	SOS2 GRB2	Interleukin-15 signaling
WP:WP422	0.00352059040085	0.333333333333	SOS2 GRB2	MAPK cascade
WP:WP4535	0.00703705758996	0.333333333333	SOS2 GRB2	Envelope proteins and their potential roles in EDMD physiopathology
KEGG:05213	0.00955265238281	0.333333333333	SOS2 GRB2	Endometrial cancer
KEGG:04664	0.00992545203512	0.333333333333	SOS2 GRB2	Fc epsilon RI signaling pathway
KEGG:05221	0.0123104747863	0.333333333333	SOS2 GRB2	Acute myeloid leukemia
REAC:R-HSA-451927	0.0135559590666	0.333333333333	SOS2 GRB2	Interleukin-2 family signaling

Showing 1 to 10 of 46 entries

Show entries

Search:

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
SOS2	GRB2	1.0	0.192		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ERRFI1	GRB2	0.998	0.202	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GRB2	GAREM2	0.985			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
SHC1	GRB2	0.976			bioplex3_HEK293 bioplex () bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
GLS2	GRB2	0.974	0.2		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
C16orf96	GRB2	0.968			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
SOS2	ERRFI1	0.844	0.09		bioplex_WMM bioplex3_WMM WMM_only
SHC1	GAREM2	0.796			bioplex3_WMM WMM_only
SHC1	SOS2	0.675			bioplex3_WMM WMM_only
C16orf96	ERRFI1	0.557			bioplex_WMM bioplex3_WMM WMM_only

Showing 1 to 10 of 21 entries

Related Complexes

Genename	Complexes
C16orf96	huMAP3_02129.1 huMAP3_04552.1 huMAP3_06243.1 huMAP3_07305.1 huMAP3_07767.1 huMAP3_08669.1 huMAP3_09299.1 huMAP3_10500.1 huMAP3_10717.1 huMAP3_12679.1 huMAP3_13626.1 huMAP3_14478.1
SOS2	huMAP3_02129.1 huMAP3_04552.1 huMAP3_06243.1 huMAP3_07305.1 huMAP3_07767.1 huMAP3_08669.1 huMAP3_09299.1 huMAP3_10500.1 huMAP3_10717.1 huMAP3_13626.1 huMAP3_14478.1
ERRFI1	huMAP3_02129.1 huMAP3_04051.1 huMAP3_07305.1 huMAP3_07767.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10717.1 huMAP3_12897.1 huMAP3_13626.1 huMAP3_14478.1
GLS2	huMAP3_02129.1 huMAP3_03848.1 huMAP3_07305.1 huMAP3_07767.1 huMAP3_08669.1 huMAP3_09299.1 huMAP3_10717.1 huMAP3_12679.1 huMAP3_13626.1 huMAP3_14478.1
GRB2	huMAP3_02129.1 huMAP3_04552.1 huMAP3_06243.1 huMAP3_07305.1 huMAP3_07767.1 huMAP3_08669.1 huMAP3_09299.1 huMAP3_10500.1 huMAP3_10717.1 huMAP3_12679.1 huMAP3_13626.1 huMAP3_14478.1
GAREM2	huMAP3_04552.1 huMAP3_04682.1 huMAP3_07305.1 huMAP3_07767.1 huMAP3_08669.1 huMAP3_09299.1 huMAP3_10500.1 huMAP3_10717.1 huMAP3_12679.1 huMAP3_13555.1 huMAP3_13626.1 huMAP3_14478.1 huMAP3_14611.1
SHC1	huMAP3_01479.1 huMAP3_04269.1 huMAP3_07305.1 huMAP3_09299.1 huMAP3_10717.1 huMAP3_12595.1 huMAP3_13555.1 huMAP3_13626.1 huMAP3_14478.1 huMAP3_14611.1 huMAP3_14845.1