hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07310.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SBDS | Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein) | 5 | UniProt NCBI |
| RBM12 | RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN) | 4 | UniProt NCBI |
| NARS1 | Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1) | 5 | UniProt NCBI |
| VRK1 | Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0570761 | 0.0273327385677 | 1.0 | SBDS VRK1 NARS1 RBM12 | testis; pachytene spermatocytes[>=Low] |
| CORUM:7101 | 0.049938562206 | 0.25 | VRK1 | AURKB-VRK1 complex |
| CORUM:7102 | 0.049938562206 | 0.25 | VRK1 | SOX2-VRK1 complex |
| CORUM:7103 | 0.049938562206 | 0.25 | VRK1 | NBS1-VRK1 complex |
| CORUM:7104 | 0.049938562206 | 0.25 | VRK1 | NBS1-RNF8-VRK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VRK1 | RBM12 | 0.988 | 0.034 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| SBDS | VRK1 | 0.983 | 0.066 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| RBM12 | NARS1 | 0.978 | 0.086 | bioplex_WMM bioplex3_WMM WMM_only |
| VRK1 | NARS1 | 0.977 | 0.068 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| SBDS | RBM12 | 0.954 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only |
| SBDS | NARS1 | 0.525 | 0.252 | bioplex_WMM bioplex3_WMM fraction |
Related Complexes