hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07313.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RAD17 | Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog) | 5 | UniProt NCBI |
| RFC2 | Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) | 5 | UniProt NCBI |
| ATAD5 | ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) | 5 | UniProt NCBI |
| RFC3 | Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) | 5 | UniProt NCBI |
| RFC5 | Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) | 5 | UniProt NCBI |
| CHTF18 | Chromosome transmission fidelity protein 18 homolog (hCTF18) (CHL12) | 5 | UniProt NCBI |
| DSCC1 | Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog) | 5 | UniProt NCBI |
| RFC4 | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) | 5 | UniProt NCBI |
| CHTF8 | Chromosome transmission fidelity protein 8 homolog (hCTF8) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003689 | 8.73322522913e-24 | 0.888888888889 | CHTF8 RFC2 CHTF18 DSCC1 RFC4 RAD17 RFC3 RFC5 | DNA clamp loader activity |
| CORUM:2804 | 1.03551099145e-22 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | CTF18-cohesion-RFC complex |
| CORUM:3070 | 8.28309551967e-22 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | CTF18-cohesion-RFC-POLH complex |
| GO:0031390 | 5.10238684012e-19 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | Ctf18 RFC-like complex |
| GO:1900262 | 2.2957989982e-18 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | regulation of DNA-directed DNA polymerase activity |
| GO:1900264 | 2.2957989982e-18 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | positive regulation of DNA-directed DNA polymerase activity |
| REAC:R-HSA-174411 | 1.98407340426e-16 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | Polymerase switching on the C-strand of the telomere |
| GO:0008094 | 5.19410736058e-16 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | ATP-dependent activity, acting on DNA |
| GO:0006275 | 9.40861674471e-16 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | regulation of DNA replication |
| REAC:R-HSA-174417 | 1.62105722654e-15 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | Telomere C-strand (Lagging Strand) Synthesis |
| CORUM:270 | 1.84180722403e-15 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | RAD17-RFC complex |
| CORUM:2202 | 1.84180722403e-15 | 0.555555555556 | RFC5 RFC2 RFC4 CHTF18 RFC3 | CHTF18-RFC2-5 complex |
| CORUM:2797 | 1.84180722403e-15 | 0.555555555556 | RFC5 RFC2 RFC4 CHTF18 RFC3 | PCNA-CHL12-RFC2-5 complex |
| CORUM:2199 | 1.84180722403e-15 | 0.555555555556 | RFC5 RFC2 RFC4 CHTF18 RFC3 | CHTF18-RFC2-5 complex |
| CORUM:2810 | 1.84180722403e-15 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | RAD17-RFC complex |
| CORUM:266 | 1.84180722403e-15 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | RAD17-RFC complex |
| GO:0017116 | 1.08590314531e-14 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | single-stranded DNA helicase activity |
| REAC:R-HSA-180786 | 3.48157606693e-14 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | Extension of Telomeres |
| CORUM:268 | 1.03070620664e-13 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | 9-1-1-RAD17-RFC complex |
| CORUM:274 | 1.03070620664e-13 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | 9-1-1-RAD17-RFC complex |
| WP:WP2363 | 2.12722263028e-13 | 0.666666666667 | CHTF8 DSCC1 CHTF18 RFC4 RAD17 RFC3 | Gastric cancer network 2 |
| GO:0140097 | 5.06572998386e-13 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | catalytic activity, acting on DNA |
| GO:0090329 | 9.77353608612e-13 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | regulation of DNA-templated DNA replication |
| GO:0006260 | 1.36489741979e-12 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | DNA replication |
| REAC:R-HSA-157579 | 4.78548687028e-12 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | Telomere Maintenance |
| CORUM:613 | 5.38212907005e-12 | 0.444444444444 | RFC3 CHTF8 CHTF18 DSCC1 | CTF18-CTF8-DCC1-RFC3 complex |
| CORUM:2201 | 5.38212907005e-12 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | PCNA-RFC2-5 complex |
| CORUM:2200 | 5.38212907005e-12 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | RFC2-5 subcomplex |
| GO:0003678 | 1.28699210815e-11 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | DNA helicase activity |
| GO:2000573 | 2.16257130824e-11 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | positive regulation of DNA biosynthetic process |
| REAC:R-HSA-73886 | 2.6626436905e-11 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | Chromosome Maintenance |
| CORUM:277 | 2.69032781214e-11 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | RFC complex |
| CORUM:2799 | 2.69032781214e-11 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | RFC complex |
| CORUM:279 | 2.69032781214e-11 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | RFC complex |
| CORUM:2203 | 8.068773772e-11 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | BRD4-RFC complex |
| CORUM:1003 | 3.76336611262e-10 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | RC complex (Replication competent complex) |
| GO:0140657 | 4.31826298196e-10 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | ATP-dependent activity |
| GO:0051052 | 5.6344143883e-10 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | regulation of DNA metabolic process |
| GO:2000278 | 8.10618321523e-10 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | regulation of DNA biosynthetic process |
| REAC:R-HSA-9709570 | 1.48631561726e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Impaired BRCA2 binding to RAD51 |
| REAC:R-HSA-5685938 | 1.73363866033e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | HDR through Single Strand Annealing (SSA) |
| REAC:R-HSA-176187 | 2.01279774624e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Activation of ATR in response to replication stress |
| GO:0051054 | 2.01961550104e-09 | 0.888888888889 | CHTF8 RFC2 DSCC1 ATAD5 CHTF18 RFC4 RFC3 RFC5 | positive regulation of DNA metabolic process |
| GO:0004386 | 2.28190972405e-09 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | helicase activity |
| GO:0140640 | 2.6826317066e-09 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | catalytic activity, acting on a nucleic acid |
| REAC:R-HSA-5693616 | 3.07191674153e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Presynaptic phase of homologous DNA pairing and strand exchange |
| REAC:R-HSA-9675136 | 3.50995957276e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Diseases of DNA Double-Strand Break Repair |
| REAC:R-HSA-9701190 | 3.50995957276e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Defective homologous recombination repair (HRR) due to BRCA2 loss of function |
| REAC:R-HSA-5693579 | 4.53557626819e-09 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Homologous DNA Pairing and Strand Exchange |
| REAC:R-HSA-9675135 | 1.01508292211e-08 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Diseases of DNA repair |
| GO:0006261 | 1.18614999938e-08 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | DNA-templated DNA replication |
| CORUM:2806 | 1.31072783286e-08 | 0.333333333333 | CHTF8 CHTF18 DSCC1 | CTF18-CTF8-DCC1 complex |
| CORUM:278 | 1.31072783286e-08 | 0.333333333333 | RFC2 RFC4 RFC5 | RFC core complex |
| CORUM:612 | 1.31072783286e-08 | 0.333333333333 | CHTF8 CHTF18 DSCC1 | CTF18-CTF8-DCC1 complex |
| GO:0071897 | 1.31155475247e-08 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | DNA biosynthetic process |
| REAC:R-HSA-69091 | 1.56854536488e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Polymerase switching |
| REAC:R-HSA-69109 | 1.56854536488e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Leading Strand Synthesis |
| GO:0005663 | 1.65724193228e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA replication factor C complex |
| REAC:R-HSA-5656121 | 2.85033862028e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Translesion synthesis by POLI |
| REAC:R-HSA-110312 | 2.85033862028e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Translesion synthesis by REV1 |
| REAC:R-HSA-1640170 | 2.90076944325e-08 | 0.888888888889 | CHTF8 RFC2 CHTF18 DSCC1 RFC4 RAD17 RFC3 RFC5 | Cell Cycle |
| KEGG:03430 | 2.95302312633e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Mismatch repair |
| REAC:R-HSA-5655862 | 3.72634490188e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Translesion synthesis by POLK |
| REAC:R-HSA-5685942 | 4.738886091e-08 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | HDR through Homologous Recombination (HRR) |
| WP:WP531 | 5.32945232105e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA mismatch repair |
| REAC:R-HSA-110320 | 6.06529448111e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Translesion Synthesis by POLH |
| REAC:R-HSA-69186 | 7.57954108849e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Lagging Strand Synthesis |
| REAC:R-HSA-5651801 | 9.3603973851e-08 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | PCNA-Dependent Long Patch Base Excision Repair |
| WP:WP5366 | 1.23941703118e-07 | 0.555555555556 | RFC5 RFC2 RFC4 RFC3 ATAD5 | NF1 copy number variation syndrome |
| GO:0006259 | 1.39363925919e-07 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | DNA metabolic process |
| REAC:R-HSA-69473 | 1.94989845738e-07 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | G2/M DNA damage checkpoint |
| KEGG:03030 | 1.95741462485e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA replication |
| REAC:R-HSA-110373 | 1.97626240808e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| REAC:R-HSA-5696397 | 1.97626240808e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Gap-filling DNA repair synthesis and ligation in GG-NER |
| REAC:R-HSA-6804756 | 2.1894157868e-07 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Regulation of TP53 Activity through Phosphorylation |
| REAC:R-HSA-5693607 | 2.31767371682e-07 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Processing of DNA double-strand break ends |
| KEGG:03410 | 4.09305244802e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Base excision repair |
| REAC:R-HSA-110314 | 4.2755177006e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Recognition of DNA damage by PCNA-containing replication complex |
| REAC:R-HSA-5656169 | 4.90758223578e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Termination of translesion DNA synthesis |
| REAC:R-HSA-69190 | 5.60712805559e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA strand elongation |
| WP:WP466 | 6.70159706378e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA replication |
| WP:WP4753 | 7.38691399834e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Nucleotide excision repair |
| REAC:R-HSA-73933 | 8.15761533179e-07 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Resolution of Abasic Sites (AP sites) |
| REAC:R-HSA-5693567 | 1.13086406247e-06 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| REAC:R-HSA-110313 | 1.14908181818e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| KEGG:03420 | 1.40136691549e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Nucleotide excision repair |
| REAC:R-HSA-5693538 | 1.43852528668e-06 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Homology Directed Repair |
| GO:0051347 | 1.53202065008e-06 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | positive regulation of transferase activity |
| REAC:R-HSA-5696400 | 1.5751787127e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Dual Incision in GG-NER |
| REAC:R-HSA-73893 | 2.76977126814e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA Damage Bypass |
| REAC:R-HSA-5633007 | 3.28925794593e-06 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Regulation of TP53 Activity |
| REAC:R-HSA-5693532 | 3.99643412879e-06 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | DNA Double-Strand Break Repair |
| REAC:R-HSA-69481 | 4.12523951296e-06 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | G2/M Checkpoints |
| WP:WP5114 | 6.46155621312e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Nucleotide excision repair in xeroderma pigmentosum |
| REAC:R-HSA-6782210 | 9.20935842442e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Gap-filling DNA repair synthesis and ligation in TC-NER |
| REAC:R-HSA-6782135 | 9.82061910807e-06 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Dual incision in TC-NER |
| REAC:R-HSA-73884 | 1.97649192365e-05 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Base Excision Repair |
| REAC:R-HSA-6781827 | 2.08422022609e-05 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| CORUM:2805 | 2.73623797451e-05 | 0.222222222222 | DSCC1 CHTF8 | CTF8-DCC1 subcomplex |
| REAC:R-HSA-5696399 | 2.82551309181e-05 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Global Genome Nucleotide Excision Repair (GG-NER) |
| GO:0005694 | 3.25389797794e-05 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | chromosome |
| WP:WP4946 | 3.78060926198e-05 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA repair pathways full network |
| GO:0051338 | 6.42580569988e-05 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | regulation of transferase activity |
| REAC:R-HSA-69620 | 6.8609480026e-05 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Cell Cycle Checkpoints |
| REAC:R-HSA-5696398 | 8.18366619652e-05 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Nucleotide Excision Repair |
| REAC:R-HSA-73894 | 0.00010855299237 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | DNA Repair |
| REAC:R-HSA-69239 | 0.000120893646135 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Synthesis of DNA |
| CORUM:6304 | 0.000164069436391 | 0.222222222222 | CHTF18 DSCC1 | DDX11-Ctf18-RFC complex |
| REAC:R-HSA-3700989 | 0.000177725731734 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Transcriptional Regulation by TP53 |
| GO:0043085 | 0.00026997045615 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | positive regulation of catalytic activity |
| REAC:R-HSA-69242 | 0.000386032040152 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | S Phase |
| CORUM:435 | 0.000409911647195 | 0.222222222222 | RFC2 RFC4 | BASC (Ab 81) complex (BRCA1-associated genome surveillance complex) |
| REAC:R-HSA-69306 | 0.000553181794813 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | DNA Replication |
| CORUM:434 | 0.000764679747525 | 0.222222222222 | RFC2 RFC4 | BASC (Ab 80) complex (BRCA1-associated genome surveillance complex) |
| WP:WP2446 | 0.00146973735431 | 0.333333333333 | RFC3 RFC4 RFC5 | Retinoblastoma gene in cancer |
| CORUM:433 | 0.00180015784734 | 0.222222222222 | RFC2 RFC4 | BASC complex (BRCA1-associated genome surveillance complex) |
| WP:WP4932 | 0.0020456158253 | 0.333333333333 | RFC2 CHTF18 RFC5 | 7q11 23 copy number variation syndrome |
| GO:0045935 | 0.00208698450598 | 0.888888888889 | CHTF8 RFC2 DSCC1 ATAD5 CHTF18 RFC4 RFC3 RFC5 | positive regulation of nucleobase-containing compound metabolic process |
| GO:0005657 | 0.00220742322002 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | replication fork |
| GO:0044093 | 0.0038382483127 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | positive regulation of molecular function |
| GO:0050790 | 0.00742080476787 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | regulation of catalytic activity |
| GO:0019219 | 0.0189408029 | 1.0 | CHTF8 RFC2 CHTF18 ATAD5 DSCC1 RFC4 RAD17 RFC3 RFC5 | regulation of nucleobase-containing compound metabolic process |
| GO:0140513 | 0.0219388544585 | 0.777777777778 | CHTF8 RFC2 DSCC1 CHTF18 RFC4 RFC3 RFC5 | nuclear protein-containing complex |
| REAC:R-HSA-212436 | 0.0395263988284 | 0.555555555556 | RFC5 RFC2 RFC4 RAD17 RFC3 | Generic Transcription Pathway |
| REAC:R-HSA-69278 | 0.0428747976055 | 0.444444444444 | RFC5 RFC2 RFC4 RFC3 | Cell Cycle, Mitotic |
| CORUM:1132 | 0.0499842271994 | 0.111111111111 | RFC4 | RFC2-RIalpha complex |
| CORUM:1131 | 0.0499842271994 | 0.111111111111 | RFC2 | RFC2-RIalpha complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RFC5 | RFC4 | 1.0 | 0.946 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| RFC2 | RFC5 | 1.0 | 0.978 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction treiber_WMM |
| RFC3 | RFC5 | 1.0 | 0.898 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction treiber_WMM |
| RFC3 | RFC4 | 1.0 | 0.802 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| DSCC1 | CHTF8 | 1.0 | 0.360666666667 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHTF18 | RFC5 | 1.0 | 0.342 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| DSCC1 | RFC3 | 1.0 | 0.368 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHTF18 | DSCC1 | 1.0 | 0.328 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHTF18 | RFC4 | 0.999 | 0.272 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| RFC2 | RFC4 | 0.999 | 0.942 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| DSCC1 | RFC5 | 0.999 | 0.464 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RFC2 | RFC3 | 0.999 | 0.948 | hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| DSCC1 | RFC2 | 0.999 | 0.388 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHTF8 | RFC5 | 0.999 | 0.322 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RAD17 | RFC4 | 0.999 | 0.228 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| DSCC1 | RFC4 | 0.999 | 0.48 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RAD17 | RFC5 | 0.999 | 0.216 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| CHTF8 | RFC4 | 0.999 | 0.38 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ATAD5 | RFC5 | 0.998 | 0.206 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| ATAD5 | RFC4 | 0.996 | 0.258 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| RAD17 | RFC3 | 0.988 | 0.204 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| RFC2 | ATAD5 | 0.986 | 0.29 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| RAD17 | RFC2 | 0.985 | 0.222 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CHTF18 | RFC2 | 0.982 | 0.316 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| CHTF18 | CHTF8 | 0.979 | 0.37 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| CHTF18 | RFC3 | 0.947 | 0.258 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| CHTF8 | RFC2 | 0.893 | 0.344 | bioplex_WMM bioplex3_WMM WMM_only |
| CHTF8 | RFC3 | 0.872 | 0.208 | bioplex_WMM bioplex3_WMM WMM_only |
| ATAD5 | RFC3 | 0.643 | 0.216 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM fraction |
| CHTF8 | RAD17 | 0.631 | 0.23 | bioplex_WMM bioplex3_WMM WMM_only |
| CHTF18 | RAD17 | 0.589 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only |
| RAD17 | ATAD5 | 0.583 | 0.144 | bioplex_WMM bioplex3_WMM WMM_only |
| DSCC1 | RAD17 | 0.535 | 0.192 | bioplex_WMM bioplex3_WMM WMM_only |
| CHTF18 | ATAD5 | 0.426 | 0.132 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| DSCC1 | ATAD5 | 0.263 | 0.162 | bioplex_WMM bioplex3_WMM WMM_only |
| CHTF8 | ATAD5 | 0.202 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes