hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07329.1

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
ATP6V1F	V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F)	5	UniProt NCBI
ATP6V1B2	V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)	5	UniProt NCBI
ATP6V1E2	V-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2)	4	UniProt NCBI
ATP6V1G3	V-type proton ATPase subunit G 3 (V-ATPase subunit G 3) (V-ATPase 13 kDa subunit 3) (Vacuolar proton pump subunit G 3)	4	UniProt NCBI
ATP6V1G1	V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)	5	UniProt NCBI
TCIRG1	V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)	5	UniProt NCBI
TLDC2	TLD domain-containing protein 2 (TBC/LysM-associated domain-containing protein 2)	2	UniProt NCBI
ATP6V1D	V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D)	5	UniProt NCBI
RAPGEF3	Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI)	5	UniProt NCBI
ATP6V1B1	V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)	5	UniProt NCBI
ATP6V1E1	V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)	5	UniProt NCBI
ROGDI	Protein rogdi homolog	5	UniProt NCBI
DMXL1	DmX-like protein 1 (X-like 1 protein)	3	UniProt NCBI
ATP6V1C1	V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)	5	UniProt NCBI
WDR7	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	3	UniProt NCBI
NCOA7	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	5	UniProt NCBI
TBC1D24	TBC1 domain family member 24	5	UniProt NCBI
ATP6V0D2	V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Vacuolar proton pump subunit d 2)	5	UniProt NCBI
ATP6V1A	V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)	5	UniProt NCBI
ATP6V1C2	V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04966	1.99941818411e-29	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Collecting duct acid secretion
REAC:R-HSA-77387	2.3088782887e-27	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Insulin receptor recycling
REAC:R-HSA-917977	2.3088782887e-27	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Transferrin endocytosis and recycling
REAC:R-HSA-1222556	1.06962053726e-26	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	ROS and RNS production in phagocytes
KEGG:05110	4.21169533704e-25	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Vibrio cholerae infection
REAC:R-HSA-917937	1.54975257532e-23	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Iron uptake and transport
GO:0016471	1.63473291313e-23	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	vacuolar proton-transporting V-type ATPase complex
REAC:R-HSA-9639288	2.00245009102e-23	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Amino acids regulate mTORC1
KEGG:04721	2.03566659124e-23	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Synaptic vesicle cycle
GO:0033176	3.1316637083e-23	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	proton-transporting V-type ATPase complex
KEGG:05120	3.87662781507e-23	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Epithelial cell signaling in Helicobacter pylori infection
KEGG:05323	1.05557048549e-22	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Rheumatoid arthritis
REAC:R-HSA-74752	1.61492822011e-22	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Signaling by Insulin receptor
GO:0016469	1.7576988985e-19	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	proton-transporting two-sector ATPase complex
KEGG:00190	1.83690930198e-19	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Oxidative phosphorylation
KEGG:04145	4.91671740037e-19	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Phagosome
REAC:R-HSA-983712	1.15814563968e-18	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Ion channel transport
GO:0033180	1.2077081575e-17	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	proton-transporting V-type ATPase, V1 domain
GO:0000221	1.2077081575e-17	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	vacuolar proton-transporting V-type ATPase, V1 domain
REAC:R-HSA-9711097	1.58421839836e-17	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Cellular response to starvation
GO:0042625	3.6206988023e-17	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	ATPase-coupled ion transmembrane transporter activity
GO:0033178	1.77222004815e-15	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	proton-transporting two-sector ATPase complex, catalytic domain
KEGG:05165	9.08623949758e-15	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Human papillomavirus infection
GO:0046961	2.93781732287e-14	0.368421052632	ATP6V1E1 ATP6V1C2 ATP6V1C1 ATP6V1E2 TCIRG1 ATP6V1B2 ATP6V1A	proton-transporting ATPase activity, rotational mechanism
GO:0044769	2.93781732287e-14	0.368421052632	ATP6V1E1 ATP6V1C2 ATP6V1C1 ATP6V1E2 TCIRG1 ATP6V1B2 ATP6V1A	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
KEGG:04150	4.1478691582e-14	0.526315789474	ATP6V1F ATP6V1B2 ATP6V1E2 ATP6V1G3 ATP6V1E1 ATP6V1D ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	mTOR signaling pathway
GO:1904949	1.36467895884e-13	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	ATPase complex
WP:WP4917	3.36332967962e-12	0.368421052632	ATP6V1F ATP6V0D2 ATP6V1E1 ATP6V1D ATP6V1G1 ATP6V1A ATP6V1C1	Proximal tubule transport
REAC:R-HSA-9006934	4.78672384698e-12	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Signaling by Receptor Tyrosine Kinases
REAC:R-HSA-382551	5.85805819455e-11	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Transport of small molecules
GO:0007035	1.04127483848e-10	0.368421052632	ATP6V1F ATP6V0D2 DMXL1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	vacuolar acidification
GO:0042626	6.64169821892e-10	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	ATPase-coupled transmembrane transporter activity
GO:0019829	8.99562409478e-10	0.368421052632	ATP6V1E1 ATP6V1C2 ATP6V1C1 ATP6V1E2 TCIRG1 ATP6V1B2 ATP6V1A	ATPase-coupled monoatomic cation transmembrane transporter activity
GO:0016241	1.49128417018e-09	0.473684210526	ATP6V1E1 ATP6V1C1 ATP6V1D ATP6V1E2 ATP6V0D2 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	regulation of macroautophagy
GO:0051452	1.95869930658e-09	0.368421052632	ATP6V1F ATP6V0D2 DMXL1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	intracellular pH reduction
REAC:R-HSA-2262752	2.15306581797e-09	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Cellular responses to stress
REAC:R-HSA-8953897	2.41129161028e-09	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Cellular responses to stimuli
GO:0005774	4.31036221845e-09	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	vacuolar membrane
GO:0015078	6.4525136503e-09	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	proton transmembrane transporter activity
GO:0016236	1.74818025844e-08	0.526315789474	ATP6V1E1 ATP6V1B2 ATP6V1D ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	macroautophagy
GO:1902600	1.75022845602e-08	0.368421052632	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	proton transmembrane transport
REAC:R-HSA-168249	2.3903969705e-08	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Innate Immune System
GO:0051453	3.31900692824e-08	0.368421052632	ATP6V1F ATP6V0D2 DMXL1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	regulation of intracellular pH
GO:0030641	4.22033598921e-08	0.368421052632	ATP6V1F ATP6V0D2 DMXL1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	regulation of cellular pH
GO:0006885	5.96143214336e-08	0.368421052632	ATP6V1F ATP6V0D2 DMXL1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	regulation of pH
GO:0015399	9.67360134696e-08	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	primary active transmembrane transporter activity
GO:0098852	1.02780374475e-07	0.526315789474	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	lytic vacuole membrane
GO:0005765	1.02780374475e-07	0.526315789474	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	lysosomal membrane
KEGG:01100	3.69516617866e-07	0.631578947368	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	Metabolic pathways
GO:0010506	1.7935452227e-06	0.473684210526	ATP6V1E1 ATP6V1C1 ATP6V1D ATP6V1E2 ATP6V0D2 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	regulation of autophagy
GO:0061919	2.33997960084e-06	0.526315789474	ATP6V1E1 ATP6V1B2 ATP6V1D ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	process utilizing autophagic mechanism
GO:0006914	2.33997960084e-06	0.526315789474	ATP6V1E1 ATP6V1B2 ATP6V1D ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	autophagy
GO:0005773	2.45862663229e-06	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	vacuole
REAC:R-HSA-168256	2.56550809958e-06	0.684210526316	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A RAPGEF3 ATP6V1C1	Immune System
REAC:R-HSA-162582	2.38646773174e-05	0.684210526316	ATP6V1F ATP6V1B2 ATP6V1D ATP6V1G3 ATP6V1E1 ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A RAPGEF3 ATP6V1C1	Signal Transduction
KEGG:04142	2.39628826273e-05	0.263157894737	DMXL1 ATP6V0D2 TCIRG1 NCOA7 WDR7	Lysosome
GO:0022853	2.48174282029e-05	0.368421052632	ATP6V1E1 ATP6V1C2 ATP6V1C1 ATP6V1E2 TCIRG1 ATP6V1B2 ATP6V1A	active monoatomic ion transmembrane transporter activity
GO:0005764	2.66589501306e-05	0.526315789474	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	lysosome
GO:0000323	2.66589501306e-05	0.526315789474	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	lytic vacuole
GO:0022804	4.3565098527e-05	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	active transmembrane transporter activity
GO:0030003	0.000112611783479	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	intracellular monoatomic cation homeostasis
GO:0006873	0.000121520833842	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	intracellular monoatomic ion homeostasis
GO:0098796	0.000142213827272	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	membrane protein complex
HP:0006891	0.000173006990273	0.157894736842	ATP6V1E1 ATP6V1A TBC1D24	Thick cerebral cortex
GO:0022890	0.000238903908154	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	inorganic cation transmembrane transporter activity
GO:0055080	0.000244476649541	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	monoatomic cation homeostasis
GO:0050801	0.000280341537254	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	monoatomic ion homeostasis
GO:0007042	0.000390461732764	0.210526315789	ATP6V1F ATP6V1A TCIRG1 ATP6V1D	lysosomal lumen acidification
GO:0031329	0.000392234917834	0.473684210526	ATP6V1E1 ATP6V1C1 ATP6V1D ATP6V1E2 ATP6V0D2 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	regulation of cellular catabolic process
GO:0008324	0.000463510778159	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	monoatomic cation transmembrane transporter activity
GO:0055082	0.000819493653878	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	intracellular chemical homeostasis
GO:0140657	0.000920893866444	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	ATP-dependent activity
GO:0015318	0.00103298270125	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	inorganic molecular entity transmembrane transporter activity
GO:0035751	0.00106605514536	0.210526315789	ATP6V1F ATP6V1A TCIRG1 ATP6V1D	regulation of lysosomal lumen pH
HP:0031423	0.00177916273632	0.105263157895	TBC1D24 ATP6V1B2	Small cerebellar cortex
GO:0015075	0.001820632374	0.421052631579	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1E2 TCIRG1 ATP6V1C2 ATP6V1A ATP6V1B2	monoatomic ion transmembrane transporter activity
GO:0019725	0.00323690422501	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	cellular homeostasis
HP:0031282	0.00533334863918	0.105263157895	TBC1D24 ATP6V1B2	Malalignment of the great toenail
HP:0025244	0.00533334863918	0.105263157895	ATP6V1E1 ATP6V1A	Subretinal pigment epithelium hemorrhage
HP:0010347	0.00533334863918	0.105263157895	TBC1D24 ATP6V1B2	Aplasia/Hypoplasia of the phalanges of the 2nd toe
HP:0010324	0.00533334863918	0.105263157895	TBC1D24 ATP6V1B2	Abnormal morphology of phalanx of the 2nd toe
CORUM:6888	0.00551005395777	0.105263157895	ATP6V1B2 ATP6V1A	v-ATPase-Ragulator-AXIN/LKB1-AMPK complex
GO:0009894	0.00998125821861	0.473684210526	ATP6V1E1 ATP6V1C1 ATP6V1D ATP6V1E2 ATP6V0D2 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1B2	regulation of catabolic process
HP:0011326	0.010658424938	0.105263157895	TBC1D24 ATP6V1B2	Anterior plagiocephaly
HP:0007457	0.010658424938	0.105263157895	ATP6V1E1 ATP6V1A	Prominent veins on trunk
GO:0061795	0.0111127441894	0.157894736842	ATP6V1F ATP6V1A ATP6V1D	Golgi lumen acidification
GO:0048388	0.0111127441894	0.157894736842	ATP6V1F ATP6V1A ATP6V1D	endosomal lumen acidification
GO:0048878	0.0126456565172	0.421052631579	ATP6V1F ATP6V1B2 DMXL1 ATP6V1D TCIRG1 ATP6V1G1 ATP6V1A ATP6V0D2	chemical homeostasis
HPA:0271153	0.01410143345	0.157894736842	ATP6V1F ATP6V1B2 ATP6V1D	kidney; proximal tubules (microvilli)[High]
GO:0098588	0.0152884422288	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	bounding membrane of organelle
HP:0031422	0.0177502656521	0.105263157895	TBC1D24 ATP6V1B2	Abnormal cerebellar cortex morphology
HP:0001305	0.019883195545	0.210526315789	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Dandy-Walker malformation
GO:0098662	0.0236596841241	0.368421052632	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	inorganic cation transmembrane transport
GO:0098655	0.025270478667	0.368421052632	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	monoatomic cation transmembrane transport
HP:0025082	0.0266047515813	0.105263157895	ATP6V1E1 ATP6V1A	Abnormal cutaneous elastic fiber morphology
HP:0025167	0.0266047515813	0.105263157895	ATP6V1E1 ATP6V1A	Fragmented elastic fibers in the dermis
GO:1902494	0.0268633044369	0.578947368421	ATP6V1F ATP6V1B2 ATP6V1E1 ATP6V1G3 ATP6V1D ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	catalytic complex
GO:0044248	0.0270494402903	0.526315789474	ATP6V1E1 ATP6V1B2 ATP6V1D ATP6V1E2 ATP6V0D2 TCIRG1 ATP6V1C2 ATP6V1G1 ATP6V1A ATP6V1C1	cellular catabolic process
HPA:0271122	0.0290406572668	0.263157894737	ATP6V1F ATP6V1D ATP6V0D2 ATP6V1B2 ATP6V1G3	kidney; collecting ducts[>=Medium]
HP:0000455	0.029356886134	0.210526315789	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Broad nasal tip
HP:0002198	0.0346973400906	0.210526315789	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Dilated fourth ventricle
HP:0010950	0.0346973400906	0.210526315789	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Abnormal fourth ventricle morphology
HP:0007552	0.0372177702968	0.105263157895	ATP6V1E1 ATP6V1A	Abnormal subcutaneous fat tissue distribution
HP:0002350	0.0396660183999	0.210526315789	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Cerebellar cyst
GO:0098660	0.0411946197267	0.368421052632	ATP6V1F ATP6V1C1 ATP6V1E1 ATP6V1D TCIRG1 ATP6V1A ATP6V1B2	inorganic ion transmembrane transport
HP:0009933	0.0495852161318	0.105263157895	ATP6V1E1 ATP6V1A	Narrow naris
HP:0025201	0.0495852161318	0.105263157895	ATP6V1E1 ATP6V1A	Abnormal circulating apolipoprotein concentration

Edges

Protein 1	Protein 2	Score	ProteomeHD
ATP6V1F	ATP6V1B2	1.0	0.462
ATP6V1B2	ATP6V1A	1.0	0.832
ATP6V1B2	ATP6V1D	1.0	0.65
ATP6V1D	ATP6V1E1	1.0	0.792
ATP6V1E2	ATP6V1C2	1.0
ATP6V1F	ATP6V1C2	1.0
ATP6V1B2	ATP6V1E1	1.0	0.93
ATP6V1D	ATP6V1A	1.0	0.548
ATP6V1B1	ATP6V1D	1.0
ATP6V1F	ATP6V1B1	1.0
ATP6V1E2	ATP6V1B1	1.0
ATP6V1B1	ATP6V1G1	1.0
TCIRG1	ATP6V0D2	1.0
ATP6V1C2	ATP6V1A	1.0
WDR7	ROGDI	1.0
ATP6V1D	ATP6V1C2	1.0
ATP6V1E1	ATP6V1A	0.999	0.816
DMXL1	ROGDI	0.999	0.11
ATP6V1E1	ATP6V1C2	0.999
ATP6V1E2	ATP6V1G1	0.999
ATP6V1B1	ATP6V1E1	0.999
ATP6V1C1	ATP6V1B1	0.999
ATP6V1B2	ATP6V1B1	0.999
ATP6V1C2	ATP6V1G1	0.999
ATP6V1E2	ATP6V1D	0.999
ATP6V1B2	ATP6V1E2	0.999
ATP6V1B2	ATP6V1C2	0.999
ATP6V1C1	ATP6V1B2	0.999	0.304
ATP6V1B1	ATP6V1A	0.999
ATP6V1E1	ATP6V1G1	0.999	0.92
ATP6V1C1	ATP6V1D	0.999	0.188
ATP6V1D	ATP6V1G1	0.999	0.7
ATP6V1F	ATP6V1D	0.999	0.924
ATP6V1F	ATP6V1G1	0.999	0.746
ATP6V1C1	ATP6V1C2	0.999
ATP6V1F	ATP6V0D2	0.999
ATP6V1C1	ATP6V1G1	0.998	0.344
ATP6V1F	ATP6V1E1	0.998	0.618
WDR7	ATP6V1B1	0.998
ATP6V1B2	ATP6V1G1	0.998	0.79
ATP6V1G1	ATP6V1A	0.998	0.844
NCOA7	ATP6V1B1	0.998
ATP6V1F	ATP6V1A	0.998	0.606
DMXL1	ATP6V1B1	0.997
ATP6V1B2	ATP6V0D2	0.997
DMXL1	ATP6V1G1	0.997	0.056
NCOA7	ATP6V1B2	0.996	0.074
NCOA7	ATP6V1G1	0.996	0.054
TBC1D24	ATP6V1G1	0.996	0.03
ATP6V1F	TCIRG1	0.995	0.06
TBC1D24	ATP6V1B2	0.994	0.078
NCOA7	ATP6V1D	0.993	0.024
ATP6V1F	ATP6V1C1	0.993	0.196
TBC1D24	ATP6V1D	0.992	0.052
ATP6V1C1	ATP6V1A	0.991	0.29
DMXL1	ATP6V1B2	0.991	0.078
ATP6V1B2	ROGDI	0.989	0.124
ATP6V1B1	ATP6V1C2	0.988
TBC1D24	ATP6V1B1	0.987
ATP6V1C1	ATP6V1E1	0.987	0.23
TCIRG1	ATP6V1B2	0.986	0.126
ATP6V0D2	ATP6V1A	0.986
ATP6V1B2	RAPGEF3	0.984	0.17
ATP6V1C1	ATP6V1E2	0.982
TCIRG1	ATP6V1E1	0.981	0.102
WDR7	ATP6V1B2	0.98
TLDC2	ATP6V1A	0.98
WDR7	DMXL1	0.978
ATP6V1F	ATP6V1E2	0.978
ATP6V1E2	ATP6V1A	0.978
ATP6V1E2	ATP6V1E1	0.978
WDR7	ATP6V1G1	0.977
DMXL1	ATP6V1C2	0.975
ATP6V1G3	ATP6V1A	0.974
ATP6V1B1	ATP6V0D2	0.973
TCIRG1	ATP6V1G1	0.97	0.134
NCOA7	ATP6V1E2	0.969
WDR7	NCOA7	0.964
NCOA7	DMXL1	0.964	0.06
NCOA7	ATP6V1C2	0.964
NCOA7	ATP6V1C1	0.964	0.078
ATP6V1D	TLDC2	0.96
ATP6V1E1	ATP6V0D2	0.96
NCOA7	ATP6V1A	0.959	0.106
DMXL1	ATP6V1E2	0.958
ATP6V1C1	TLDC2	0.957
WDR7	ATP6V1E2	0.957
ATP6V1D	ATP6V0D2	0.957
ATP6V1B2	ATP6V1G3	0.955
ATP6V1C1	ATP6V0D2	0.955
TCIRG1	ATP6V1A	0.953	0.146
WDR7	ATP6V1C2	0.952
ATP6V1F	NCOA7	0.952	0.028
ATP6V0D2	ATP6V1G1	0.95
ATP6V1B2	TLDC2	0.95
TCIRG1	ATP6V1C1	0.947	0.156
WDR7	ATP6V1C1	0.946
DMXL1	ATP6V1C1	0.946	0.108
DMXL1	ATP6V1D	0.946	0.064
ATP6V1F	DMXL1	0.946	0.032
DMXL1	ATP6V1E1	0.946	0.044
DMXL1	ATP6V1A	0.946	0.076
NCOA7	ATP6V1E1	0.936	0.052
WDR7	ATP6V1E1	0.933
WDR7	ATP6V1D	0.933
ATP6V1F	WDR7	0.931
TCIRG1	ATP6V1D	0.927	0.072
ATP6V1E1	TLDC2	0.922
ATP6V1G1	TLDC2	0.92
WDR7	ATP6V1A	0.912
DMXL1	ATP6V0D2	0.904
WDR7	ATP6V0D2	0.904
NCOA7	ATP6V0D2	0.879
TBC1D24	ATP6V0D2	0.849
ATP6V1C2	ATP6V0D2	0.837
ATP6V1E2	ATP6V0D2	0.834
TBC1D24	WDR7	0.799
TBC1D24	DMXL1	0.799	0.022
ATP6V1F	TLDC2	0.789
TBC1D24	ATP6V1A	0.674	0.13
TBC1D24	ATP6V1E2	0.672
TBC1D24	NCOA7	0.672	0.058
TBC1D24	ATP6V1C1	0.654	0.11
TBC1D24	ATP6V1E1	0.654	0.046
TBC1D24	ATP6V1C2	0.646
ATP6V1F	TBC1D24	0.618	0.086
ATP6V1E1	ATP6V1G3	0.605
TCIRG1	ATP6V1E2	0.451
TCIRG1	ATP6V1C2	0.433
WDR7	RAPGEF3	0.415
ATP6V1E2	RAPGEF3	0.415
ATP6V1B1	ROGDI	0.415
ATP6V1B1	RAPGEF3	0.415
DMXL1	RAPGEF3	0.415	0.082
NCOA7	RAPGEF3	0.415	0.072
RAPGEF3	ROGDI	0.415	0.066
RAPGEF3	ATP6V1A	0.385	0.095
RAPGEF3	ATP6V1G1	0.297	0.102
ATP6V1C2	RAPGEF3	0.278
ATP6V1E2	ROGDI	0.274
ATP6V1C1	RAPGEF3	0.274	0.094
NCOA7	ROGDI	0.274	0.056
ATP6V1E1	RAPGEF3	0.254	0.06
ATP6V1D	RAPGEF3	0.21	0.144
TCIRG1	DMXL1	0.173	0.064
TCIRG1	WDR7	0.173
TCIRG1	NCOA7	0.128	0.028
ATP6V1C2	ROGDI	0.113
ATP6V1C1	ROGDI	0.113	0.076
ATP6V1E1	ROGDI	0.113	0.056
TBC1D24	RAPGEF3	0.113	0.042
TBC1D24	TCIRG1	0.106	0.034
ATP6V1F	RAPGEF3	0.093	0.06
ATP6V1F	ROGDI	0.089	0.066
ATP6V1D	ROGDI	0.078	0.042
TBC1D24	ROGDI	0.076	0.11
TCIRG1	ATP6V1B1	0.057
RAPGEF3	ATP6V0D2	0.046
TCIRG1	RAPGEF3	0.043	0.096
TCIRG1	ROGDI	0.042	0.062
ROGDI	ATP6V0D2	0.042
ROGDI	ATP6V1A	0.035	0.094
ROGDI	ATP6V1G1	0.029	0.07

Related Complexes

Genename	Complexes
ATP6V1F	huMAP3_00308.1 huMAP3_01501.1 huMAP3_05444.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1B2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1E2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1G3	huMAP3_05070.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1G1	huMAP3_01501.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
TCIRG1	huMAP3_01038.1 huMAP3_01501.1 huMAP3_02239.1 huMAP3_05374.1 huMAP3_05805.1 huMAP3_07329.1 huMAP3_07558.1 huMAP3_08032.1 huMAP3_08182.1 huMAP3_08678.1 huMAP3_09324.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13060.1 huMAP3_13872.1
TLDC2	huMAP3_05070.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1D	huMAP3_01413.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
RAPGEF3	huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1B1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1E1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ROGDI	huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_05952.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
DMXL1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1C1	huMAP3_01413.1 huMAP3_05070.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
WDR7	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
NCOA7	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
TBC1D24	huMAP3_00552.1 huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13467.1 huMAP3_13872.1
ATP6V0D2	huMAP3_01501.1 huMAP3_05083.1 huMAP3_05318.1 huMAP3_05805.1 huMAP3_07329.1 huMAP3_07510.1 huMAP3_08166.1 huMAP3_08182.1 huMAP3_08678.1 huMAP3_09477.1 huMAP3_09562.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1A	huMAP3_05070.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1C2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_12827.1 huMAP3_13872.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07329.1