hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07372.1
Complex Portal: CPX-21543
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COPRS | Coordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1) | 5 | UniProt NCBI |
| HNRNPH1 | Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] | 5 | UniProt NCBI |
| HNRNPH2 | Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0570771 | 0.00554387032948 | 1.0 | COPRS HNRNPH1 HNRNPH2 | testis; peritubular cells[>=Low] |
| HPA:0461423 | 0.00704427967728 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; eccrine glands[High] |
| WP:WP411 | 0.00831500934109 | 0.666666666667 | HNRNPH1 HNRNPH2 | mRNA processing |
| HPA:0570763 | 0.0119453326684 | 1.0 | COPRS HNRNPH1 HNRNPH2 | testis; pachytene spermatocytes[High] |
| HPA:0471493 | 0.0144360249621 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[High] |
| HPA:0461493 | 0.0163771345036 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[High] |
| HPA:0461422 | 0.0302328294218 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; eccrine glands[>=Medium] |
| HPA:0461492 | 0.0316049848456 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[>=Medium] |
| HPA:0471492 | 0.0323023843332 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[>=Medium] |
| HP:0001211 | 0.0368991311611 | 0.666666666667 | HNRNPH1 HNRNPH2 | Abnormal fingertip morphology |
| HPA:0461413 | 0.037395322848 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; cells in spinous layer[High] |
| HPA:0461463 | 0.0412590843677 | 0.666666666667 | HNRNPH1 HNRNPH2 | skin 1; langerhans cells[High] |
| HPA:0570782 | 0.0440355061936 | 1.0 | COPRS HNRNPH1 HNRNPH2 | testis; preleptotene spermatocytes[>=Medium] |
| HPA:0570813 | 0.0443510461782 | 1.0 | COPRS HNRNPH1 HNRNPH2 | testis; spermatogonia cells[High] |
| HPA:0380203 | 0.0491179252569 | 0.666666666667 | HNRNPH1 HNRNPH2 | placenta; endothelial cells[High] |
| CORUM:1287 | 0.0499402709677 | 0.333333333333 | HNRNPH1 | HNRPF-HNRPH1 complex |
| CORUM:6853 | 0.0499402709677 | 0.333333333333 | COPRS | COPRS-PRMT5 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| COPRS | HNRNPH2 | 0.995 | 0.088 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| HNRNPH1 | HNRNPH2 | 0.992 | 0.626 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| COPRS | HNRNPH1 | 0.952 | 0.224615384615 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM WMM_only |
Related Complexes