hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07376.1
Complex Portal: CPX-17721
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C4BPA | C4b-binding protein alpha chain (C4bp) (Proline-rich protein) (PRP) | 5 | UniProt NCBI |
| C5 | Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain] | 5 | UniProt NCBI |
| PHF11 | PHD finger protein 11 (BRCA1 C-terminus-associated protein) (Renal carcinoma antigen NY-REN-34) | 5 | UniProt NCBI |
| ANKRD22 | Ankyrin repeat domain-containing protein 22 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05133 | 0.00426927356048 | 0.5 | C4BPA C5 | Pertussis |
| KEGG:04610 | 0.00619374956043 | 0.5 | C4BPA C5 | Complement and coagulation cascades |
| WP:WP2806 | 0.00742144474402 | 0.5 | C4BPA C5 | Complement system |
| REAC:R-HSA-977606 | 0.00837722051003 | 0.5 | C4BPA C5 | Regulation of Complement cascade |
| WP:WP5090 | 0.00992155513194 | 0.5 | C4BPA C5 | Complement system in neuronal development and plasticity |
| REAC:R-HSA-166658 | 0.0115164156767 | 0.5 | C4BPA C5 | Complement cascade |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| C5 | PHF11 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C4BPA | PHF11 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ANKRD22 | PHF11 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C4BPA | ANKRD22 | 0.634 | bioplex3_WMM WMM_only | ||
| C5 | ANKRD22 | 0.634 | bioplex3_WMM WMM_only | ||
| C5 | C4BPA | 0.534 | 0.236 | bioplex3_WMM WMM_only |
Related Complexes