hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07387.1
Complex Portal: CPX-19271
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BIRC2 | Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2) | 5 | UniProt NCBI |
| DIABLO | Diablo IAP-binding mitochondrial protein (Diablo homolog, mitochondrial) (Direct IAP-binding protein with low pI) (Second mitochondria-derived activator of caspase) (Smac) [Cleaved into: Diablo IAP-binding mitochondrial protein, cleaved form] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04215 | 6.60032959562e-05 | 1.0 | BIRC2 DIABLO | Apoptosis - multiple species |
| WP:WP254 | 0.00111857408398 | 1.0 | BIRC2 DIABLO | Apoptosis |
| KEGG:04210 | 0.00116074761854 | 1.0 | BIRC2 DIABLO | Apoptosis |
| WP:WP1772 | 0.00127818796583 | 1.0 | BIRC2 DIABLO | Apoptosis modulation and signaling |
| WP:WP231 | 0.00148377064565 | 1.0 | BIRC2 DIABLO | TNF alpha signaling pathway |
| REAC:R-HSA-109581 | 0.0234014921954 | 1.0 | BIRC2 DIABLO | Apoptosis |
| GO:0035631 | 0.0257510396046 | 1.0 | BIRC2 DIABLO | CD40 receptor complex |
| REAC:R-HSA-5357801 | 0.0319897287616 | 1.0 | BIRC2 DIABLO | Programmed Cell Death |
| CORUM:5529 | 0.0499419797295 | 0.5 | BIRC2 | TRAF2-cIAP1/BIRC2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BIRC2 | DIABLO | 1.0 | 0.128 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes