hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07396.1
Complex Portal: CPX-24913
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL17RC | Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14) | 5 | UniProt NCBI |
| TMEM219 | Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219) | 4 | UniProt NCBI |
| KCNJ11 | ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11) | 5 | UniProt NCBI |
| DISP1 | Protein dispatched homolog 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002686 | 0.0176079483787 | 0.5 | KCNJ11 DISP1 | Pregnancy history |
| HP:0009800 | 0.0176079483787 | 0.5 | KCNJ11 DISP1 | Maternal diabetes |
| HP:0032443 | 0.0176079483787 | 0.5 | KCNJ11 DISP1 | Past medical history |
| WP:WP5256 | 0.049746753544 | 0.25 | IL17RC | COVID 19 and endothelial cell senescence |
| CORUM:6654 | 0.049938562206 | 0.25 | KCNJ11 | KCNJ11-ABCC9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DISP1 | IL17RC | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| KCNJ11 | IL17RC | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| IL17RC | TMEM219 | 0.955 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| DISP1 | TMEM219 | 0.213 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DISP1 | KCNJ11 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNJ11 | TMEM219 | 0.097 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes