hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07426.1
Complex Portal: CPX-19689
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PARP9 | Protein mono-ADP-ribosyltransferase PARP9 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein) (Poly [ADP-ribose] polymerase 9) (PARP-9) | 5 | UniProt NCBI |
| DTX3L | E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7384 | 1.70876175213e-06 | 1.0 | PARP9 DTX3L | DTX3L-PARP9 complex |
| CORUM:7385 | 5.12628525639e-06 | 1.0 | PARP9 DTX3L | DTX3L-PARP9-STAT1 complex |
| GO:0097677 | 0.00468200720083 | 1.0 | PARP9 DTX3L | STAT family protein binding |
| GO:0035563 | 0.016855225923 | 1.0 | PARP9 DTX3L | positive regulation of chromatin binding |
| GO:0035561 | 0.0257510396046 | 1.0 | PARP9 DTX3L | regulation of chromatin binding |
| CORUM:7286 | 0.0499419797295 | 0.5 | DTX3L | AIP4-DTX3L complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DTX3L | PARP9 | 0.988 | 0.548 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| PARP9 | huMAP3_02080.1 huMAP3_07426.1 huMAP3_11498.1 huMAP3_14741.1 |
| DTX3L | huMAP3_00126.1 huMAP3_02080.1 huMAP3_07426.1 huMAP3_11498.1 huMAP3_14741.1 |