hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07431.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARSK | Arylsulfatase K (ASK) (EC 3.1.6.1) (Glucuronate-2-sulfatase) (EC 3.1.6.18) (Telethon sulfatase) | 5 | UniProt NCBI |
| CLSTN1 | Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] | 5 | UniProt NCBI |
| CHST14 | Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1) (hD4ST1) | 5 | UniProt NCBI |
| PLXNA1 | Plexin-A1 (Semaphorin receptor NOV) | 5 | UniProt NCBI |
| EXT2 | Exostosin-2 (EC 2.4.1.224) (Exostosin glycosyltransferase 2) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 2) | 5 | UniProt NCBI |
| LRFN3 | Leucine-rich repeat and fibronectin type-III domain-containing protein 3 (Synaptic adhesion-like molecule 4) | 5 | UniProt NCBI |
| CNTNAP3 | Contactin-associated protein-like 3 (Cell recognition molecule Caspr3) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4784 | 0.00271530250843 | 0.285714285714 | EXT2 CHST14 | Proteoglycan biosynthesis |
| HP:0004425 | 0.0109736833289 | 0.285714285714 | EXT2 CHST14 | Flat forehead |
| WP:WP5395 | 0.0124193659106 | 0.285714285714 | EXT2 CHST14 | Glycosaminoglycan synthesis in fibroblasts |
| REAC:R-HSA-3560782 | 0.0265716665994 | 0.285714285714 | EXT2 CHST14 | Diseases associated with glycosaminoglycan metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CLSTN1 | CNTNAP3 | 0.986 | 0.12 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PLXNA1 | CNTNAP3 | 0.979 | 0.094 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| EXT2 | CNTNAP3 | 0.979 | 0.118 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| ARSK | CNTNAP3 | 0.978 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only |
| LRFN3 | CNTNAP3 | 0.973 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| CHST14 | CNTNAP3 | 0.968 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only |
| CLSTN1 | EXT2 | 0.959 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only |
| CLSTN1 | PLXNA1 | 0.958 | 0.054 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| LRFN3 | ARSK | 0.957 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARSK | CHST14 | 0.955 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only |
| LRFN3 | PLXNA1 | 0.955 | bioplex_WMM bioplex3_WMM WMM_only | |
| LRFN3 | EXT2 | 0.954 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLXNA1 | EXT2 | 0.952 | 0.238 | bioplex_WMM bioplex3_WMM WMM_only |
| CHST14 | EXT2 | 0.95 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LRFN3 | CHST14 | 0.947 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARSK | PLXNA1 | 0.931 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| ARSK | EXT2 | 0.918 | 0.122 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| CLSTN1 | CHST14 | 0.916 | 0.152 | bioplex_WMM bioplex3_WMM WMM_only |
| CHST14 | PLXNA1 | 0.81 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LRFN3 | CLSTN1 | 0.483 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARSK | CLSTN1 | 0.333 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ARSK | huMAP3_07431.1 huMAP3_08802.1 huMAP3_09327.1 |
| CLSTN1 | huMAP3_07431.1 huMAP3_08661.1 huMAP3_09327.1 huMAP3_11573.1 |
| CHST14 | huMAP3_07431.1 huMAP3_09327.1 |
| PLXNA1 | huMAP3_07431.1 huMAP3_09327.1 |
| EXT2 | huMAP3_07431.1 huMAP3_08802.1 huMAP3_09327.1 huMAP3_12411.1 |
| LRFN3 | huMAP3_04832.1 huMAP3_06449.1 huMAP3_07431.1 huMAP3_09327.1 huMAP3_10706.1 |
| CNTNAP3 | huMAP3_07431.1 huMAP3_08661.1 huMAP3_09327.1 |