hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07434.1
Complex Portal: CPX-14527
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GMPPA | Mannose-1-phosphate guanyltransferase alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha) | 5 | UniProt NCBI |
| TMEM101 | Transmembrane protein 101 (Putative NF-kappa-B-activating protein 130) | 4 | UniProt NCBI |
| GOLPH3 | Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS) | 5 | UniProt NCBI |
| GMPPB | Mannose-1-phosphate guanyltransferase beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-446205 | 0.000102497642323 | 0.5 | GMPPB GMPPA | Synthesis of GDP-mannose |
| KEGG:00051 | 0.0014030052018 | 0.5 | GMPPB GMPPA | Fructose and mannose metabolism |
| KEGG:01250 | 0.00148789987369 | 0.5 | GMPPB GMPPA | Biosynthesis of nucleotide sugars |
| KEGG:00520 | 0.00247340401034 | 0.5 | GMPPB GMPPA | Amino sugar and nucleotide sugar metabolism |
| WP:WP5153 | 0.00324158330579 | 0.5 | GMPPB GMPPA | N glycan biosynthesis |
| REAC:R-HSA-446219 | 0.0168610262513 | 0.5 | GMPPB GMPPA | Synthesis of substrates in N-glycan biosythesis |
| KEGG:01240 | 0.0220824431074 | 0.5 | GMPPB GMPPA | Biosynthesis of cofactors |
| REAC:R-HSA-446193 | 0.0267695204965 | 0.5 | GMPPB GMPPA | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GMPPA | GMPPB | 1.0 | 0.838 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM bioplex3_HCT116 fraction | |
| GMPPA | GOLPH3 | 0.997 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GMPPB | GOLPH3 | 0.984 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GOLPH3 | TMEM101 | 0.973 | 0.122 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes