List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_07442.1

Confidence: Very High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
PDE3A	cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE)	5	UniProt   NCBI
PDE3B	cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04924	0.000183378615366	1.0	PDE3A PDE3B	Renin secretion
WP:WP4222	0.000299222823835	1.0	PDE3A PDE3B	Phosphodiesterases in neuronal function
KEGG:05032	0.00037033376401	1.0	PDE3A PDE3B	Morphine addiction
GO:0004119	0.000468200720083	1.0	PDE3A PDE3B	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
KEGG:00230	0.000772693757832	1.0	PDE3A PDE3B	Purine metabolism
KEGG:04022	0.00125991513217	1.0	PDE3A PDE3B	cGMP-PKG signaling pathway
KEGG:04024	0.00201635192055	1.0	PDE3A PDE3B	cAMP signaling pathway
REAC:R-HSA-418555	0.00715287669441	1.0	PDE3A PDE3B	G alpha (s) signalling events
GO:0043951	0.016855225923	1.0	PDE3A PDE3B	negative regulation of cAMP-mediated signaling
GO:0004115	0.0309012475255	1.0	PDE3A PDE3B	3',5'-cyclic-AMP phosphodiesterase activity
GO:0043949	0.0491610756088	1.0	PDE3A PDE3B	regulation of cAMP-mediated signaling
REAC:R-HSA-165160	0.0499419797295	0.5	PDE3B	PDE3B signalling
REAC:R-HSA-109703	0.0499419797295	0.5	PDE3B	PKB-mediated events



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
PDE3A	PDE3B	0.994	0.26	bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only





Related Complexes

Genename	Complexes
PDE3A	huMAP3_00621.1 huMAP3_01638.1 huMAP3_07442.1 huMAP3_12808.1
PDE3B	huMAP3_00621.1 huMAP3_07442.1 huMAP3_09065.1 huMAP3_10409.1 huMAP3_15113.1