hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07447.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NETO1 | Neuropilin and tolloid-like protein 1 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1) | 5 | UniProt NCBI |
| CHST11 | Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) | 5 | UniProt NCBI |
| ST6GALNAC6 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase VI) (ST6GalNAc VI) (ST6GalNAcVI) (hST6GalNAc VI) (Sialyltransferase 7F) (SIAT7-F) | 5 | UniProt NCBI |
| OCA2 | P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog) | 5 | UniProt NCBI |
| CHRNB2 | Neuronal acetylcholine receptor subunit beta-2 | 5 | UniProt NCBI |
| DSE | Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00532 | 0.0013768061199 | 0.333333333333 | CHST11 DSE | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
| WP:WP5395 | 0.00703705758996 | 0.333333333333 | CHST11 DSE | Glycosaminoglycan synthesis in fibroblasts |
| REAC:R-HSA-71387 | 0.0187811350588 | 0.5 | CHST11 ST6GALNAC6 DSE | Metabolism of carbohydrates |
| REAC:R-HSA-1793185 | 0.0265097243254 | 0.333333333333 | CHST11 DSE | Chondroitin sulfate/dermatan sulfate metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CHRNB2 | ST6GALNAC6 | 0.978 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| OCA2 | CHRNB2 | 0.975 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CHST11 | CHRNB2 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CHRNB2 | NETO1 | 0.961 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CHRNB2 | DSE | 0.953 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| OCA2 | NETO1 | 0.415 | bioplex3_WMM WMM_only | |
| OCA2 | ST6GALNAC6 | 0.415 | bioplex3_WMM WMM_only | |
| ST6GALNAC6 | NETO1 | 0.415 | bioplex3_WMM WMM_only | |
| CHST11 | DSE | 0.402 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only |
| CHST11 | ST6GALNAC6 | 0.25 | bioplex3_WMM WMM_only | |
| OCA2 | DSE | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | |
| CHST11 | OCA2 | 0.113 | bioplex3_WMM WMM_only | |
| CHST11 | NETO1 | 0.113 | bioplex3_WMM WMM_only | |
| DSE | NETO1 | 0.076 | bioplex3_WMM WMM_only | |
| DSE | ST6GALNAC6 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes