hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07462.1

Complex Portal: CPX-19953

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
ZFYVE27	Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27)	5	UniProt NCBI
STARD3NL	STARD3 N-terminal-like protein (MLN64 N-terminal domain homolog)	5	UniProt NCBI
ATP5PO	ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP)	5	UniProt NCBI
ACKR3	Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1)	5	UniProt NCBI
ATP5F1A	ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha)	5	UniProt NCBI
SLC43A3	Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)	5	UniProt NCBI
ATP5MF	ATP synthase subunit f, mitochondrial (ATP synthase membrane subunit f)	5	UniProt NCBI
ATP5MK	ATP synthase membrane subunit K, mitochondrial (ATP synthase membrane subunit DAPIT, mitochondrial) (Diabetes-associated protein in insulin-sensitive tissues) (HCV F-transactivated protein 2) (Up-regulated during skeletal muscle growth protein 5)	5	UniProt NCBI
ATP5MG	ATP synthase subunit g, mitochondrial (ATPase subunit g) (ATP synthase membrane subunit g)	4	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:563	1.54229147311e-06	0.428571428571	ATP5PO ATP5MF ATP5MG	F1F0-ATP synthase, mitochondrial
GO:0005753	5.49646107354e-06	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	mitochondrial proton-transporting ATP synthase complex
GO:0045259	5.49646107354e-06	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	proton-transporting ATP synthase complex
REAC:R-HSA-163210	1.06075342669e-05	0.428571428571	ATP5PO ATP5MF ATP5MG	Formation of ATP by chemiosmotic coupling
REAC:R-HSA-8949613	5.26476903505e-05	0.428571428571	ATP5PO ATP5MF ATP5MG	Cristae formation
GO:0016469	0.00012419921232	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	proton-transporting two-sector ATPase complex
WP:WP623	0.000195860613826	0.428571428571	ATP5PO ATP5MF ATP5MG	Oxidative phosphorylation
GO:0015986	0.000835286748042	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	proton motive force-driven ATP synthesis
WP:WP111	0.000909018580113	0.428571428571	ATP5PO ATP5MF ATP5MG	Electron transport chain OXPHOS system in mitochondria
KEGG:00190	0.00101170562286	0.428571428571	ATP5PO ATP5MF ATP5MG	Oxidative phosphorylation
REAC:R-HSA-1592230	0.00131187888511	0.428571428571	ATP5PO ATP5MF ATP5MG	Mitochondrial biogenesis
GO:0006754	0.00159023569175	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ATP biosynthetic process
GO:0009145	0.00175371310235	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine nucleoside triphosphate biosynthetic process
GO:0009206	0.00175371310235	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine ribonucleoside triphosphate biosynthetic process
GO:0046933	0.00187892941497	0.428571428571	ATP5PO ATP5MF ATP5MG	proton-transporting ATP synthase activity, rotational mechanism
GO:0009201	0.00221735123044	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ribonucleoside triphosphate biosynthetic process
GO:0009142	0.002536243155	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	nucleoside triphosphate biosynthetic process
REAC:R-HSA-163200	0.00366502300707	0.428571428571	ATP5PO ATP5MF ATP5MG	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
GO:0015252	0.00445787546995	0.428571428571	ATP5PO ATP5MF ATP5MG	proton channel activity
KEGG:04714	0.00476603793812	0.428571428571	ATP5PO ATP5MF ATP5MG	Thermogenesis
REAC:R-HSA-1428517	0.00995795730546	0.428571428571	ATP5PO ATP5MF ATP5MG	The citric acid (TCA) cycle and respiratory electron transport
GO:1904949	0.0134125272986	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ATPase complex
GO:0098800	0.0167951236507	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	inner mitochondrial membrane protein complex
GO:0009152	0.0218746163137	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine ribonucleotide biosynthetic process
GO:0046034	0.0267004712888	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ATP metabolic process
GO:0009260	0.0273552115046	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ribonucleotide biosynthetic process
GO:0046390	0.031538799442	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ribose phosphate biosynthetic process
GO:0009205	0.0353751608722	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine ribonucleoside triphosphate metabolic process
GO:0009144	0.0370032799768	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine nucleoside triphosphate metabolic process
GO:0009199	0.0404265697107	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	ribonucleoside triphosphate metabolic process
REAC:R-HSA-1852241	0.0422635503964	0.428571428571	ATP5PO ATP5MF ATP5MG	Organelle biogenesis and maintenance
GO:0006164	0.0440807990477	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine nucleotide biosynthetic process
GO:0009141	0.0469790462071	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	nucleoside triphosphate metabolic process
GO:0072522	0.0489886309445	0.571428571429	ATP5PO ATP5MG ATP5MF ATP5MK	purine-containing compound biosynthetic process

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ATP5F1A	ATP5MF	0.999	0.836		hein_WMM bioplex_WMM Guru bioplex3_WMM boldt fraction boldt_WMM
ATP5PO	ATP5F1A	0.999	0.93	structurally_consistent (dimer)	hein_WMM bioplex_WMM Guru bioplex3_WMM boldt hein () fraction boldt_WMM treiber_WMM
ATP5PO	ATP5MG	0.999	0.972		bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM
ZFYVE27	ATP5PO	0.998	0.178	structurally_consistent (P25705)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ZFYVE27	ATP5F1A	0.997	0.154	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ATP5F1A	ATP5MG	0.995	0.888		hein_WMM bioplex_WMM Guru bioplex3_WMM boldt fraction boldt_WMM
ATP5PO	STARD3NL	0.993	0.108		bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
ATP5MF	ATP5MG	0.991	0.906		hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only
STARD3NL	ATP5MG	0.989	0.146		bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
SLC43A3	STARD3NL	0.988	0.104		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ATP5F1A	STARD3NL	0.986	0.266		bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
ATP5PO	ATP5MF	0.982	0.952		bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM treiber_WMM WMM_only
ATP5PO	ATP5MK	0.978	0.562		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only
ATP5MK	ATP5F1A	0.977	0.756		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
ATP5PO	ACKR3	0.977	0.096		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein ()
ATP5MF	STARD3NL	0.976	0.076		bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
SLC43A3	ATP5PO	0.975	0.108		hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ZFYVE27	ATP5MG	0.972	0.16		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
SLC43A3	ATP5MG	0.965	0.054		hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ATP5MK	ATP5MG	0.962	0.78		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only
SLC43A3	ATP5F1A	0.956	0.188		hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
ATP5MK	ATP5MF	0.955	0.708		hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only
ACKR3	ATP5F1A	0.937	0.144		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein ()
ZFYVE27	ATP5MF	0.933	0.168		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
SLC43A3	ATP5MF	0.771	0.058		bioplex3_WMM bioplex3_HCT116 WMM_only
ACKR3	ATP5MF	0.286	0.062		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ACKR3	ATP5MG	0.168	0.076		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ZFYVE27	STARD3NL	0.081	0.248		bioplex3_WMM WMM_only
ATP5MK	STARD3NL	0.051	0.074		bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
ZFYVE27	SLC43A3	0.042	0.07		bioplex3_WMM WMM_only
SLC43A3	ATP5MK	0.018	0.054		hein_WMM WMM_only
ZFYVE27	ATP5MK	0.005	0.15		youn_WMM WMM_only

Related Complexes

Genename	Complexes
ZFYVE27	huMAP3_00060.1 huMAP3_01732.1 huMAP3_02673.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
STARD3NL	huMAP3_04279.1 huMAP3_06247.1 huMAP3_07410.1 huMAP3_07462.1 huMAP3_09307.1 huMAP3_09589.1 huMAP3_09592.1 huMAP3_11095.1
ATP5PO	huMAP3_00261.1 huMAP3_01649.1 huMAP3_03298.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08080.1 huMAP3_08510.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_10245.1 huMAP3_11095.1
ACKR3	huMAP3_00261.1 huMAP3_01649.1 huMAP3_07462.1 huMAP3_08080.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_10245.1 huMAP3_11095.1 huMAP3_13050.1 huMAP3_13265.1 huMAP3_14222.1 huMAP3_14441.1
ATP5F1A	huMAP3_00261.1 huMAP3_07245.1 huMAP3_07462.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_10473.1 huMAP3_11095.1
SLC43A3	huMAP3_00060.1 huMAP3_01732.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5MF	huMAP3_00261.1 huMAP3_06247.1 huMAP3_07410.1 huMAP3_07462.1 huMAP3_07480.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09592.1 huMAP3_11095.1
ATP5MK	huMAP3_00261.1 huMAP3_02620.1 huMAP3_06601.1 huMAP3_07462.1 huMAP3_08750.1 huMAP3_09153.1 huMAP3_09307.1 huMAP3_10473.1 huMAP3_10607.1 huMAP3_11095.1
ATP5MG	huMAP3_06247.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07462.1

Complex Portal: CPX-19953