hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07463.1
Complex Portal: CPX-22777
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CFAP74 | Cilia- and flagella-associated protein 74 | 5 | UniProt NCBI |
| PDE9A | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35) | 5 | UniProt NCBI |
| PALD1 | Paladin | 4 | UniProt NCBI |
| UNC119 | Protein unc-119 homolog A (Retinal protein 4) (hRG4) | 5 | UniProt NCBI |
| UNC119B | Protein unc-119 homolog B | 5 | UniProt NCBI |
| SPDEF | SAM pointed domain-containing Ets transcription factor (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets) (Prostate-derived Ets factor) | 5 | UniProt NCBI |
| RSPRY1 | RING finger and SPRY domain-containing protein 1 | 4 | UniProt NCBI |
| CYS1 | Cystin-1 (Cilia-associated protein) | 4 | UniProt NCBI |
| PSKH2 | Serine/threonine-protein kinase H2 (EC 2.7.11.1) (Protein serine kinase H2) (PSK-H2) | 5 | UniProt NCBI |
| LZTS1 | Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5624138 | 0.00101671361746 | 0.2 | CYS1 UNC119B | Trafficking of myristoylated proteins to the cilium |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| UNC119 | UNC119B | 1.0 | 0.32 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| PALD1 | UNC119 | 0.999 | 0.066 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| PDE9A | UNC119 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| UNC119 | LZTS1 | 0.998 | 0.036 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| UNC119 | PSKH2 | 0.998 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PALD1 | UNC119B | 0.997 | 0.014 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| PSKH2 | UNC119B | 0.997 |
structurally_consistent (Q13432)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| UNC119 | SPDEF | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CYS1 | UNC119B | 0.994 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| UNC119 | CYS1 | 0.985 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| UNC119 | RSPRY1 | 0.977 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| RSPRY1 | UNC119B | 0.977 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SPDEF | UNC119B | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| UNC119B | LZTS1 | 0.955 | 0.04 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PDE9A | PALD1 | 0.918 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| PDE9A | LZTS1 | 0.916 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PDE9A | RSPRY1 | 0.693 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| PDE9A | UNC119B | 0.605 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PALD1 | LZTS1 | 0.582 | 0.072 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PALD1 | RSPRY1 | 0.468 | 0.036 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| RSPRY1 | LZTS1 | 0.408 | 0.118 | bioplex_WMM bioplex3_WMM WMM_only | |
| RSPRY1 | CFAP74 | 0.063 | bioplex3_WMM WMM_only |
Related Complexes