hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07476.1

Complex Portal: CPX-14031

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
ATP5PD	ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d)	5	UniProt NCBI
ATP5F1D	ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit)	5	UniProt NCBI
ATP5F1E	ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon)	5	UniProt NCBI
MT-ATP8	ATP synthase protein 8 (A6L) (F-ATPase subunit 8)	5	UniProt NCBI
ATP5PB	ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b)	5	UniProt NCBI
ZFYVE27	Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27)	5	UniProt NCBI
KDSR	3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)	5	UniProt NCBI
ATP5PO	ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP)	5	UniProt NCBI
ATP5F1C	ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit)	5	UniProt NCBI
ATP5F1B	ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta)	5	UniProt NCBI
ATP5ME	ATP synthase subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) [Cleaved into: ATP synthase subunit e, mitochondrial, N-terminally processed]	4	UniProt NCBI
CERS6	Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291)	5	UniProt NCBI
ATP5MG	ATP synthase subunit g, mitochondrial (ATPase subunit g) (ATP synthase membrane subunit g)	4	UniProt NCBI
ATP5PF	ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6)	5	UniProt NCBI
SLC43A3	Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3)	5	UniProt NCBI
MT-ATP6	ATP synthase subunit a (F-ATPase protein 6)	5	UniProt NCBI
RETREG3	Reticulophagy regulator 3	5	UniProt NCBI
ATP5IF1	ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:563	7.87179907918e-29	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	F1F0-ATP synthase, mitochondrial
REAC:R-HSA-163210	8.68301436897e-22	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Formation of ATP by chemiosmotic coupling
GO:0046933	3.41443923459e-20	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton-transporting ATP synthase activity, rotational mechanism
REAC:R-HSA-8949613	2.54378230033e-19	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Cristae formation
GO:0045259	8.75656729129e-19	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton-transporting ATP synthase complex
GO:0005753	8.75656729129e-19	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	mitochondrial proton-transporting ATP synthase complex
GO:0015252	8.75656729129e-19	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton channel activity
WP:WP111	3.72220085011e-17	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Electron transport chain OXPHOS system in mitochondria
GO:0016469	2.09408844435e-15	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton-transporting two-sector ATPase complex
REAC:R-HSA-1592230	8.00811444547e-15	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Mitochondrial biogenesis
KEGG:00190	3.99071129983e-14	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Oxidative phosphorylation
GO:0042776	6.9420554428e-14	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton motive force-driven mitochondrial ATP synthesis
GO:0015986	1.90257424833e-13	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton motive force-driven ATP synthesis
REAC:R-HSA-163200	1.94184113985e-13	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
GO:0006754	8.53521512544e-13	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ATP biosynthetic process
GO:0009206	1.07141147603e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine ribonucleoside triphosphate biosynthetic process
GO:0009145	1.07141147603e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine nucleoside triphosphate biosynthetic process
GO:0009201	1.84647318448e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ribonucleoside triphosphate biosynthetic process
GO:0015078	2.52088885023e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	proton transmembrane transporter activity
GO:0009142	2.52088885023e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleoside triphosphate biosynthetic process
GO:0046034	3.65492156016e-12	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ATP metabolic process
REAC:R-HSA-1428517	4.2130820138e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	The citric acid (TCA) cycle and respiratory electron transport
KEGG:04714	4.67778175509e-12	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Thermogenesis
GO:0009205	7.48986684954e-12	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine ribonucleoside triphosphate metabolic process
GO:0009144	8.39997556745e-12	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine nucleoside triphosphate metabolic process
WP:WP623	8.4309135032e-12	0.466666666667	ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5PO ATP5MG ATP5F1E	Oxidative phosphorylation
GO:0009199	1.05241167358e-11	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ribonucleoside triphosphate metabolic process
GO:0009141	1.54286463956e-11	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleoside triphosphate metabolic process
GO:0006119	2.56942045323e-11	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	oxidative phosphorylation
GO:1904949	1.16838830587e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ATPase complex
GO:0016874	1.42246086743e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ligase activity
GO:0098800	1.95609780466e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	inner mitochondrial membrane protein complex
GO:0009060	2.21499068721e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	aerobic respiration
REAC:R-HSA-1852241	3.52397018386e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	Organelle biogenesis and maintenance
GO:0009152	3.58137903733e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine ribonucleotide biosynthetic process
GO:0009260	5.97123815825e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ribonucleotide biosynthetic process
GO:0045333	7.03584696304e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	cellular respiration
GO:0046390	8.26561190732e-10	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ribose phosphate biosynthetic process
GO:0006164	1.77496912183e-09	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine nucleotide biosynthetic process
GO:0072522	2.25819040479e-09	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine-containing compound biosynthetic process
GO:0009150	2.48209779787e-09	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine ribonucleotide metabolic process
GO:0005261	3.27623567945e-09	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	monoatomic cation channel activity
GO:0009259	3.40059654408e-09	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ribonucleotide metabolic process
GO:0009165	4.6824005713e-09	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleotide biosynthetic process
GO:0006091	4.89824268783e-09	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	generation of precursor metabolites and energy
GO:0019693	4.89824268783e-09	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	ribose phosphate metabolic process
GO:1901293	5.56838184852e-09	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleoside phosphate biosynthetic process
GO:0015980	8.81855156112e-09	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	energy derivation by oxidation of organic compounds
KEGG:05415	1.39551769443e-08	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Diabetic cardiomyopathy
GO:0006163	1.72455921116e-08	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine nucleotide metabolic process
GO:0072521	2.60148719851e-08	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	purine-containing compound metabolic process
KEGG:05208	2.90113208128e-08	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Chemical carcinogenesis - reactive oxygen species
GO:0005216	3.93244745856e-08	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	monoatomic ion channel activity
GO:0009117	4.35194551134e-08	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleotide metabolic process
GO:0006753	5.01671360784e-08	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleoside phosphate metabolic process
GO:0098798	8.12386380981e-08	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	mitochondrial protein-containing complex
KEGG:05012	9.13135389129e-08	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Parkinson disease
GO:0015267	1.01112135842e-07	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	channel activity
GO:0022803	1.04277178303e-07	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	passive transmembrane transporter activity
KEGG:05020	1.11763123938e-07	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Prion disease
KEGG:01100	1.43794681469e-07	0.733333333333	CERS6 ATP5F1C KDSR ATP5ME ATP5PD ATP5F1E MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1B	Metabolic pathways
GO:0055086	1.65509479854e-07	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	nucleobase-containing small molecule metabolic process
KEGG:05016	2.25459541461e-07	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Huntington disease
GO:0022890	3.97664679453e-07	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	inorganic cation transmembrane transporter activity
GO:0045261	5.38102340533e-07	0.266666666667	ATP5PO ATP5F1B ATP5F1E ATP5F1C	proton-transporting ATP synthase complex, catalytic core F(1)
KEGG:05014	7.77107477866e-07	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Amyotrophic lateral sclerosis
GO:0008324	8.48973998327e-07	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	monoatomic cation transmembrane transporter activity
KEGG:05010	1.08385645848e-06	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Alzheimer disease
GO:0005743	1.45662078881e-06	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	mitochondrial inner membrane
GO:0015318	2.12690158776e-06	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	inorganic molecular entity transmembrane transporter activity
GO:0019866	2.42160613244e-06	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	organelle inner membrane
GO:0090407	3.32212638906e-06	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	organophosphate biosynthetic process
WP:WP4932	3.48672630097e-06	0.333333333333	ATP5PO ATP5F1B ATP5F1E MT-ATP6 MT-ATP8	7q11 23 copy number variation syndrome
GO:1901566	3.50436351186e-06	0.8	CERS6 ATP5F1C KDSR ATP5ME ATP5IF1 ATP5PD ATP5F1E MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1B	organonitrogen compound biosynthetic process
GO:0015075	4.07619064645e-06	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	monoatomic ion transmembrane transporter activity
KEGG:05022	4.19528301469e-06	0.466666666667	ATP5F1C ATP5PD ATP5F1B MT-ATP6 ATP5PO MT-ATP8 ATP5F1E	Pathways of neurodegeneration - multiple diseases
GO:0022857	6.43321198501e-06	0.666666666667	ATP5F1C ATP5ME SLC43A3 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	transmembrane transporter activity
GO:1901137	1.0225650214e-05	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	carbohydrate derivative biosynthetic process
GO:0019637	1.21119309339e-05	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	organophosphate metabolic process
GO:0005215	1.95751607439e-05	0.666666666667	ATP5F1C ATP5ME SLC43A3 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	transporter activity
REAC:R-HSA-1430728	2.07304343362e-05	0.733333333333	CERS6 ATP5F1C KDSR ATP5ME ATP5PD ATP5F1E MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1B	Metabolism
GO:1901135	2.3621942201e-05	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	carbohydrate derivative metabolic process
GO:0031966	2.90177648716e-05	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	mitochondrial membrane
GO:0005740	5.16190721408e-05	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	mitochondrial envelope
GO:0044281	7.33830731779e-05	0.733333333333	ATP5F1C KDSR ATP5ME ATP5IF1 ATP5PD ATP5F1E MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1B	small molecule metabolic process
GO:0033178	8.4814831801e-05	0.266666666667	ATP5PO ATP5F1B ATP5F1E ATP5F1C	proton-transporting two-sector ATPase complex, catalytic domain
GO:0000275	0.000436807598019	0.2	ATP5F1B ATP5F1E ATP5F1C	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
HP:0001987	0.000833319686423	0.266666666667	ATP5F1B ATP5F1E MT-ATP6 MT-ATP8	Hyperammonemia
GO:0000276	0.00244160521127	0.2	ATP5PD ATP5MG ATP5PO	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0045263	0.00244160521127	0.2	ATP5PD ATP5MG ATP5PO	proton-transporting ATP synthase complex, coupling factor F(o)
HP:0003535	0.00249132827704	0.2	ATP5F1E MT-ATP6 MT-ATP8	3-Methylglutaconic aciduria
GO:0005739	0.00257839348686	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	mitochondrion
GO:0031967	0.00269871197064	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	organelle envelope
GO:0031975	0.00269871197064	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	envelope
GO:0098796	0.00272422155888	0.6	ATP5F1C ATP5ME ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	membrane protein complex
HP:0001258	0.0031970456143	0.266666666667	ZFYVE27 ATP5F1E MT-ATP6 MT-ATP8	Spastic paraplegia
HP:0002445	0.00739493145726	0.2	ATP5F1E MT-ATP6 MT-ATP8	Tetraplegia
GO:0031090	0.0074891046373	0.8	CERS6 ATP5F1C KDSR ATP5F1B ATP5ME ATP5PD ZFYVE27 MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	organelle membrane
HP:0010550	0.00790059230054	0.266666666667	ZFYVE27 ATP5F1E MT-ATP6 MT-ATP8	Paraplegia
GO:0033177	0.00956840807496	0.2	ATP5PD ATP5MG ATP5PO	proton-transporting two-sector ATPase complex, proton-transporting domain
HPA:0290403	0.011856542586	0.4	ATP5F1C KDSR ATP5ME ATP5PD ATP5F1B ATP5IF1	liver; hepatocytes[High]
HP:0003112	0.0140413940495	0.266666666667	ATP5F1B ATP5F1E MT-ATP6 MT-ATP8	Abnormal circulating amino acid concentration
HP:0002157	0.014420013041	0.266666666667	ATP5F1B ATP5F1E MT-ATP6 MT-ATP8	Azotemia
HPA:0271111	0.0152261714989	0.266666666667	ATP5PD ATP5ME ATP5IF1 ATP5PO	kidney; bowman's capsule[>=Low]
HPA:0271123	0.0164443887679	0.266666666667	ATP5PD ATP5ME ATP5IF1 ATP5PO	kidney; collecting ducts[High]
HPA:0271143	0.0172085821051	0.266666666667	ATP5PD ATP5ME ATP5IF1 ATP5PO	kidney; proximal tubules (cell body)[High]
HPA:0100212	0.0182052003769	0.6	CERS6 ATP5F1C KDSR ATP5ME ATP5PD ATP5F1B ATP5MG ATP5PO ATP5IF1	cerebral cortex; neuropil[>=Medium]
WP:WP5194	0.0184937836061	0.133333333333	KDSR CERS6	Synthesis of ceramides and 1 deoxyceramides
HP:0004364	0.0186336136568	0.266666666667	ATP5F1B ATP5F1E MT-ATP6 MT-ATP8	Abnormal circulating nitrogen compound concentration
WP:WP4725	0.0249384248701	0.133333333333	KDSR CERS6	Sphingolipid metabolism overview
HPA:0271133	0.0259933594837	0.266666666667	ATP5PD ATP5ME ATP5IF1 ATP5PO	kidney; distal tubules[High]
WP:WP4726	0.0272973213504	0.133333333333	KDSR CERS6	Sphingolipid metabolism integrated pathway
HP:0003348	0.0337496428299	0.2	ATP5F1E MT-ATP6 MT-ATP8	Hyperalaninemia
HP:0010915	0.035443864971	0.2	ATP5F1E MT-ATP6 MT-ATP8	Abnormal circulating pyruvate family amino acid concentration
HP:0010916	0.035443864971	0.2	ATP5F1E MT-ATP6 MT-ATP8	Abnormal circulating alanine concentration
WP:WP1422	0.0377812718473	0.133333333333	KDSR CERS6	Sphingolipid pathway
HP:0010551	0.0390919743069	0.266666666667	ZFYVE27 ATP5F1E MT-ATP6 MT-ATP8	Paraplegia/paraparesis
HP:0002061	0.0476799439421	0.266666666667	ZFYVE27 ATP5F1E MT-ATP6 MT-ATP8	Lower limb spasticity
GO:0000274	0.0491610756088	0.133333333333	ATP5PD ATP5PO	mitochondrial proton-transporting ATP synthase, stator stalk
GO:0045265	0.0491610756088	0.133333333333	ATP5PD ATP5PO	proton-transporting ATP synthase, stator stalk
GO:0006796	0.0493897944568	0.666666666667	ATP5F1C ATP5ME ATP5IF1 ATP5PD ATP5F1B MT-ATP6 ATP5MG ATP5PO MT-ATP8 ATP5F1E	phosphate-containing compound metabolic process

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ATP5F1D	ATP5PB	1.0	0.934
ATP5PO	ATP5ME	1.0	0.956
ATP5PB	ATP5ME	1.0	0.96
ATP5PF	ATP5PO	1.0	0.828
ATP5F1D	ATP5PO	1.0	0.922	structurally_consistent (P25705)
ATP5F1D	ATP5F1B	1.0	0.896	structurally_consistent (P36542)
ATP5F1D	ATP5ME	1.0	0.87
ATP5PD	ATP5PB	1.0	0.93	structurally_consistent (dimer)
ATP5F1D	ATP5F1C	1.0	0.9	structurally_consistent (dimer)
ATP5PB	ATP5MG	1.0	0.93	structurally_consistent (dimer)
ATP5F1C	ATP5F1B	1.0	0.972	structurally_consistent (dimer)
ATP5PD	ATP5F1D	1.0	0.926	structurally_consistent (P25705)
ATP5PB	ATP5PO	1.0	0.958	structurally_consistent (dimer)
ATP5PD	ATP5ME	1.0	0.916
ATP5F1D	ATP5MG	1.0	0.826
ATP5F1D	ATP5PF	1.0	0.82
ATP5PF	ATP5ME	1.0	0.902
ATP5F1D	ATP5F1E	1.0	0.88
ATP5PD	ATP5PO	1.0	0.96
ATP5PD	ATP5F1B	1.0	0.892
ATP5ME	ATP5MG	1.0	0.908
ATP5PO	ATP5F1B	1.0	0.964	structurally_consistent (dimer)
ATP5PB	ATP5PF	1.0	0.908	structurally_consistent (dimer)
ATP5F1B	ATP5MG	1.0	0.916
ATP5F1C	ATP5MG	1.0	0.964
ATP5PF	ATP5F1C	1.0	0.856
ATP5PO	ATP5F1C	1.0	0.974	structurally_consistent (P25705)
ATP5PB	ATP5F1B	1.0	0.938	structurally_consistent (P48047)
ATP5PB	MT-ATP6	1.0	0.826	structurally_consistent (dimer)
ATP5PD	ATP5PF	1.0	0.914
ATP5PF	ATP5F1B	0.999	0.832
ATP5PD	ATP5F1C	0.999	0.886	structurally_consistent (P00846)
ATP5PB	ATP5F1C	0.999	0.962	structurally_consistent (P00846)
ATP5ME	ATP5F1B	0.999	0.922
ATP5PF	MT-ATP6	0.999	0.938	structurally_consistent (P24539)
ATP5F1D	MT-ATP6	0.999	0.898
ATP5ME	ATP5F1C	0.999	0.754
ATP5PF	ATP5MG	0.999	0.922	structurally_consistent (P24539)
ATP5PD	ATP5MG	0.999	0.976	structurally_consistent (P24539)
ATP5PF	ATP5F1E	0.999	0.71
ZFYVE27	ATP5PB	0.999	0.09
ATP5PO	ATP5MG	0.999	0.972
MT-ATP8	ATP5PF	0.998	0.752
MT-ATP8	MT-ATP6	0.998	0.408
ATP5PB	MT-ATP8	0.998	0.728
ATP5PD	RETREG3	0.998	0.08
ATP5PD	KDSR	0.998	0.116
ATP5ME	ATP5F1E	0.998	0.914
ZFYVE27	ATP5PO	0.998	0.178	structurally_consistent (P25705)
ATP5IF1	ATP5PO	0.997	0.488
KDSR	ATP5MG	0.997	0.118
MT-ATP6	ATP5F1B	0.997	0.816
KDSR	ATP5F1C	0.997	0.21
ATP5PO	ATP5F1E	0.997	0.714
MT-ATP6	ATP5PO	0.997	0.834	structurally_consistent (P24539)
ATP5PF	ATP5IF1	0.997	0.472
MT-ATP8	ATP5PO	0.997	0.704
RETREG3	ATP5MG	0.997	0.088
ATP5IF1	ATP5F1E	0.997	0.556
SLC43A3	ATP5F1B	0.996	0.172
ZFYVE27	ATP5PF	0.996	0.134
ATP5F1E	ATP5MG	0.996	0.802
ATP5PD	ATP5IF1	0.996	0.728	structurally_consistent (dimer)
MT-ATP6	ATP5ME	0.996	0.914
ATP5PO	KDSR	0.996	0.326
MT-ATP6	ATP5MG	0.995	0.858	structurally_consistent (P24539)
ATP5PD	ATP5F1E	0.995	0.728
ATP5F1D	ATP5IF1	0.995	0.424
KDSR	ATP5F1B	0.995	0.288
RETREG3	ATP5F1B	0.994	0.118
MT-ATP6	RETREG3	0.994	0.058
ATP5F1C	ATP5F1E	0.994	0.762	structurally_consistent (dimer)
MT-ATP8	ATP5F1B	0.994	0.682
ZFYVE27	ATP5F1B	0.994	0.11
ATP5F1E	ATP5F1B	0.994	0.72
ATP5PD	MT-ATP6	0.994	0.84	structurally_consistent (dimer)
ATP5F1D	MT-ATP8	0.994	0.676
ATP5PB	ATP5IF1	0.993	0.684
MT-ATP6	ATP5IF1	0.993	0.248	structurally_consistent (O75947)
MT-ATP6	ATP5F1C	0.993	0.872	structurally_consistent (dimer)
KDSR	RETREG3	0.993	0.076
ATP5PF	KDSR	0.992	0.082
MT-ATP8	ATP5ME	0.992	0.654
MT-ATP8	ATP5F1C	0.992	0.67
ZFYVE27	ATP5F1C	0.992	0.092
ATP5PB	ATP5F1E	0.991	0.64
RETREG3	CERS6	0.991	0.088
ATP5PB	SLC43A3	0.99	0.126
ATP5IF1	ATP5ME	0.99	0.256
ATP5PO	RETREG3	0.99	0.186
ATP5PB	KDSR	0.99	0.154
ATP5PD	ZFYVE27	0.989	0.136
ATP5PF	CERS6	0.989	0.066
ATP5PB	CERS6	0.988	0.116
ZFYVE27	ATP5ME	0.988	0.096
ATP5ME	KDSR	0.987	0.084
MT-ATP8	CERS6	0.986	0.042
ATP5F1B	CERS6	0.985	0.104
ATP5PO	CERS6	0.985	0.062
MT-ATP8	ATP5IF1	0.984	0.114
ATP5ME	CERS6	0.984	0.08
ATP5PB	RETREG3	0.983	0.104
ATP5PD	SLC43A3	0.981	0.092
MT-ATP8	KDSR	0.98	0.106
ATP5IF1	ATP5F1B	0.98	0.546
ATP5PD	CERS6	0.978	0.132
ATP5F1C	CERS6	0.976	0.09
ATP5F1D	CERS6	0.976	0.128
ATP5PF	RETREG3	0.975	0.08
KDSR	CERS6	0.975	0.094	structurally_consistent (dimer)
SLC43A3	ATP5PO	0.975	0.108
ATP5IF1	KDSR	0.972	0.048
ZFYVE27	ATP5MG	0.972	0.16
ZFYVE27	MT-ATP8	0.969	0.058
SLC43A3	ATP5MG	0.965	0.054
MT-ATP8	ATP5F1E	0.964	0.296
MT-ATP8	ATP5MG	0.963	0.676
ATP5PD	MT-ATP8	0.961	0.632
ATP5IF1	RETREG3	0.959	0.042
ATP5F1D	KDSR	0.957	0.216
ZFYVE27	ATP5F1E	0.956	0.09
MT-ATP6	KDSR	0.956	0.122
MT-ATP6	CERS6	0.954	0.148
ATP5ME	RETREG3	0.951	0.058
CERS6	ATP5MG	0.948	0.116
ATP5IF1	ATP5MG	0.938	0.502
ATP5F1E	CERS6	0.933	0.086
ATP5F1D	ZFYVE27	0.931	0.092
SLC43A3	ATP5ME	0.929	0.028
MT-ATP8	RETREG3	0.928	0.056
ATP5IF1	CERS6	0.919	0.068
RETREG3	ATP5F1C	0.912	0.15
SLC43A3	ATP5PF	0.91	0.082
ZFYVE27	ATP5IF1	0.895	0.068
ATP5IF1	ATP5F1C	0.878	0.438
SLC43A3	ATP5F1C	0.86	0.058
SLC43A3	KDSR	0.857	0.034
ATP5F1D	SLC43A3	0.828	0.106
MT-ATP6	ATP5F1E	0.816	0.864	structurally_consistent (P36542)
RETREG3	ATP5F1E	0.748	0.102
ZFYVE27	KDSR	0.656	0.106
ATP5F1D	RETREG3	0.595	0.06
SLC43A3	ATP5F1E	0.586	0.066
ZFYVE27	RETREG3	0.565	0.12
SLC43A3	CERS6	0.434	0.1
KDSR	ATP5F1E	0.431	0.11
SLC43A3	RETREG3	0.401	0.052
SLC43A3	ATP5IF1	0.386	0.058
MT-ATP8	SLC43A3	0.372	0.04
SLC43A3	MT-ATP6	0.357	0.034
ZFYVE27	CERS6	0.094	0.184
ZFYVE27	MT-ATP6	0.076	0.102
ZFYVE27	SLC43A3	0.042	0.07

Related Complexes

Genename	Complexes
ATP5PD	huMAP3_00060.1 huMAP3_01732.1 huMAP3_05994.1 huMAP3_06247.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5F1D	huMAP3_00060.1 huMAP3_05738.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13050.1 huMAP3_13265.1
ATP5F1E	huMAP3_03298.1 huMAP3_03963.1 huMAP3_05738.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13050.1
MT-ATP8	huMAP3_00060.1 huMAP3_00114.1 huMAP3_07476.1 huMAP3_07490.1 huMAP3_07895.1 huMAP3_08716.1 huMAP3_09488.1 huMAP3_09775.1 huMAP3_11095.1
ATP5PB	huMAP3_00060.1 huMAP3_01732.1 huMAP3_05994.1 huMAP3_06247.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ZFYVE27	huMAP3_00060.1 huMAP3_01732.1 huMAP3_02673.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
KDSR	huMAP3_02455.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_11095.1
ATP5PO	huMAP3_00261.1 huMAP3_01649.1 huMAP3_03298.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08080.1 huMAP3_08510.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_10245.1 huMAP3_11095.1
ATP5F1C	huMAP3_03298.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5F1B	huMAP3_03963.1 huMAP3_05738.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5ME	huMAP3_01731.1 huMAP3_03947.1 huMAP3_07476.1 huMAP3_07490.1 huMAP3_07895.1 huMAP3_08716.1 huMAP3_09488.1 huMAP3_09775.1 huMAP3_11095.1
CERS6	huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5MG	huMAP3_06247.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
ATP5PF	huMAP3_00060.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
SLC43A3	huMAP3_00060.1 huMAP3_01732.1 huMAP3_07462.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_08750.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
MT-ATP6	huMAP3_00060.1 huMAP3_01732.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1
RETREG3	huMAP3_02455.1 huMAP3_05994.1 huMAP3_07476.1 huMAP3_08393.1 huMAP3_09307.1 huMAP3_09584.1 huMAP3_11095.1
ATP5IF1	huMAP3_00060.1 huMAP3_00425.1 huMAP3_07476.1 huMAP3_08716.1 huMAP3_09307.1 huMAP3_09775.1 huMAP3_11095.1 huMAP3_13050.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07476.1

Complex Portal: CPX-14031