hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07497.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UQCRH | Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein) | 5 | UniProt NCBI |
| UQCRC2 | Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) | 5 | UniProt NCBI |
| UQCR10 | Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Cytochrome c1 non-heme 7 kDa protein) (Ubiquinol-cytochrome c reductase complex 7.2 kDa protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4921 | 4.4691886917e-05 | 1.0 | UQCRH UQCR10 | Mitochondrial complex III assembly |
| KEGG:04260 | 0.000415528139074 | 1.0 | UQCRH UQCR10 | Cardiac muscle contraction |
| KEGG:00190 | 0.00119992691491 | 1.0 | UQCRH UQCR10 | Oxidative phosphorylation |
| KEGG:04932 | 0.00155920593969 | 1.0 | UQCRH UQCR10 | Non-alcoholic fatty liver disease |
| WP:WP111 | 0.00202305274778 | 1.0 | UQCRH UQCR10 | Electron transport chain OXPHOS system in mitochondria |
| KEGG:05415 | 0.00267768543767 | 1.0 | UQCRH UQCR10 | Diabetic cardiomyopathy |
| GO:0008121 | 0.0028092043205 | 1.0 | UQCRH UQCR10 | ubiquinol-cytochrome-c reductase activity |
| KEGG:05208 | 0.0033003273675 | 1.0 | UQCRH UQCR10 | Chemical carcinogenesis - reactive oxygen species |
| KEGG:04714 | 0.00339933231144 | 1.0 | UQCRH UQCR10 | Thermogenesis |
| WP:WP4396 | 0.00396523446209 | 1.0 | UQCRH UQCR10 | Nonalcoholic fatty liver disease |
| KEGG:05012 | 0.00458495309323 | 1.0 | UQCRH UQCR10 | Parkinson disease |
| GO:0016679 | 0.00468200720083 | 1.0 | UQCRH UQCR10 | oxidoreductase activity, acting on diphenols and related substances as donors |
| KEGG:05020 | 0.00485920816781 | 1.0 | UQCRH UQCR10 | Prion disease |
| KEGG:05016 | 0.00594761227231 | 1.0 | UQCRH UQCR10 | Huntington disease |
| REAC:R-HSA-611105 | 0.00828920325958 | 1.0 | UQCRH UQCR10 | Respiratory electron transport |
| KEGG:05014 | 0.00850662183301 | 1.0 | UQCRH UQCR10 | Amyotrophic lateral sclerosis |
| KEGG:05010 | 0.0093688914925 | 1.0 | UQCRH UQCR10 | Alzheimer disease |
| REAC:R-HSA-163200 | 0.0124056103205 | 1.0 | UQCRH UQCR10 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| KEGG:05022 | 0.0138982457502 | 1.0 | UQCRH UQCR10 | Pathways of neurodegeneration - multiple diseases |
| REAC:R-HSA-1428517 | 0.0242575818332 | 1.0 | UQCRH UQCR10 | The citric acid (TCA) cycle and respiratory electron transport |
| GO:0006122 | 0.0257510396046 | 1.0 | UQCRH UQCR10 | mitochondrial electron transport, ubiquinol to cytochrome c |
| GO:0045275 | 0.0309012475255 | 1.0 | UQCRH UQCR10 | respiratory chain complex III |
| GO:0005750 | 0.0309012475255 | 1.0 | UQCRH UQCR10 | mitochondrial respiratory chain complex III |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UQCRH | UQCR10 | 0.997 | 0.932 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| UQCRC2 | UQCR10 | 0.984 | 0.58 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| UQCRH | UQCRC2 | 0.978 | 0.686 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM |
Related Complexes