hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07504.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LATS2 | Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase) | 5 | UniProt NCBI |
| LATS1 | Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) | 5 | UniProt NCBI |
| MYOZ1 | Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4533 | 0.000173183276299 | 0.666666666667 | LATS2 LATS1 | Transcription co factors SKI and SKIL protein partners |
| WP:WP4537 | 0.000193548942551 | 0.666666666667 | LATS2 LATS1 | Hippo YAP signaling |
| KEGG:04392 | 0.000247823846667 | 0.666666666667 | LATS2 LATS1 | Hippo signaling pathway - multiple species |
| WP:WP4542 | 0.000459327445001 | 0.666666666667 | LATS2 LATS1 | Leukocyte intrinsic Hippo pathway functions |
| REAC:R-HSA-2028269 | 0.0011650518872 | 0.666666666667 | LATS2 LATS1 | Signaling by Hippo |
| WP:WP4540 | 0.00374811209074 | 0.666666666667 | LATS2 LATS1 | Hippo signaling regulation pathways |
| WP:WP4541 | 0.00514316015145 | 0.666666666667 | LATS2 LATS1 | Hippo Merlin signaling dysregulation |
| KEGG:04390 | 0.00802719593767 | 0.666666666667 | LATS2 LATS1 | Hippo signaling pathway |
| GO:0048638 | 0.0328130751425 | 1.0 | LATS2 MYOZ1 LATS1 | regulation of developmental growth |
| CORUM:6660 | 0.0499402709677 | 0.333333333333 | LATS1 | LATS1-NPHP4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LATS1 | MYOZ1 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LATS1 | LATS2 | 0.995 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| MYOZ1 | LATS2 | 0.214 | bioplex3_WMM WMM_only |
Related Complexes