hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07508.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UNC119 | Protein unc-119 homolog A (Retinal protein 4) (hRG4) | 5 | UniProt NCBI |
| PDE9A | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35) | 5 | UniProt NCBI |
| PRKG2 | cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII) | 5 | UniProt NCBI |
| RFTN1 | Raftlin (Cell migration-inducing gene 2 protein) (Raft-linking protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-418457 | 0.000676052383047 | 0.5 | PRKG2 PDE9A | cGMP effects |
| REAC:R-HSA-392154 | 0.0013924419067 | 0.5 | PRKG2 PDE9A | Nitric oxide stimulates guanylate cyclase |
| REAC:R-HSA-418346 | 0.0260384914588 | 0.5 | PRKG2 PDE9A | Platelet homeostasis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PDE9A | UNC119 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| UNC119 | RFTN1 | 0.983 | 0.036 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| UNC119 | PRKG2 | 0.966 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| PDE9A | RFTN1 | 0.896 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDE9A | PRKG2 | 0.65 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PRKG2 | RFTN1 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes